COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF TWO COMMERCIALLY AVAILABLE HERBAL AND NON-HERBAL (FLUORIDATED) TOOTHPASTES ON SALIVARY MICROBIAL COUNT: AN IN-VIVO STUDY
Dental caries is a complex disease which is expressed as an interaction between various factors including the host, agent, substrate and time. The interplay between the dental biofilm and oral microorganisms is an important feature for development of a cariogenic dental plaque. Formation of the biofilm needs to be controlled through regular brushing in order to prevent the development of caries an...
The present study deals with the Pharmacognostical and preliminary phytochemical studies of fruit pulp of Aegle marmelos. Macroscopy, organoleptic characters, microscopic features, physiochemical standardization parameters such as total ash, acid insoluble ash, water soluble ash, alcohol, water and other organic solvent extractives, preliminary phytochemical assay, fluorescence analysis and microb...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ZALTOPROFEN AND PARACETAMOL IN COMBINED DOSAGE FORM BY ULTRAVIOLET SPECTROPHOTOMETRY
Two spectrophotometric methods are presented for the simultaneous estimation of Zaltoprofen (ZLT) and Paracetamol (PAR) in laboratory prepared mixture and pharmaceutical dosage form without prior separation. Method (1) is simultaneous equation method (Vierodt’s method); which depends on the fact that absorbance of a mixture is the sum of the individual absorbance of the components. Method (2) is...
IMPACT OF PROBIOTICS LACTOBACILLUS RHAMNOSUS AND LACTOBACILLUS CASEI ON LIPOGLYCEMIC AND ANTIOXIDATIVE STATUS OF DIABETIC RATS
Probiotics are live microorganisms, which when administered in adequate amounts confer a health benefit. There are very limited studies on antidiabetic effect of lactic acid bacteria despite their potentiality in reducing the risk of diabetes onset. The present study explored the effect of administering live culture of L. rhamnosus [MTCC No 8712] and L. casei [MTCC No 1408] in STZ induced diab...
EXTRACTION AND SECONDARY METABOLITE ANALYSIS OF COSCINIUM FENESTRATUM (GAERTN.) COLEBR: AN IMPORTANT MEDICINAL PLANT OF WESTERN GHATS
The aim of this study was to extract the secondary metabolites of Coscinium fenestratum stem extracts and to determine the alkaloid berberine using HPLC. Phytochemical analysis was carried for acetone, chloroform, methanol and Aqueous fractions of stem extracts. Total phenolic content and total flavonoid contents were estimated using standard Gallic acid and Quercitin respectively. TLC and HPLC we...
The aim of this article was to develop pidotimod dispersible tablet and optimize the ingredients for the tablets. The effect of ingredients (diluents, disintegrants and lubricants) on the characteristics of the tablets was evaluated. The pidotimod dispersible tablets were prepared by wet granulation. The effect of diluents on the tablets was investigated by Carr’s index, dissolution, hardness, f...
STUDY ON PRELIMINARY PHYTOCHEMICAL AND ANTIBACTERIAL ACTIVITY AGAINST HUMAN PATHOGENS OF AN ENDANGERED ORCHID-HABENARIA PLANTAGINEA LINDL
Habenaria plantaginea Lindl. (Orchidaceae) is used as a medicinal plant in several countries. In this study, ethanol, chloroform and water extracts of Habenaria plantaginea were evaluated for antibacterial activity against bacterial (MTCC) strains. Antibacterial activity of this plants extracts were performed using agar disc diffusion method. The antibacterial activity of ethanol extracts showed m...
PHYTOCHEMICAL INVESTIGATION AND BIOLOGICAL ASSESSMENT OF 12-HYDROXY-OCTADEC-CIS-9-ENOIC ACID ISOLATED FROM SWIETENIA HUMILIS ZUCC. SEED OIL
The genus Swietenia belongs to Meliaceae family which consists of 37 genera and about 300 species which is found in most of the parts of India. In present investigation we made an efficient effort to extract ricinoleic acid from the seed oil of Swietenia humilis, Zucc. They are used in medicine folklore to cure various diseases in Mexico, Africa and India. Physicochemical properties of Swietenia h...
Acetone extracts of the three medicinal plants Sida cardifolia, Phyllanthus amarus and Adathoda vasica were assessed for phytochemical components qualitatively and quantitatively and antioxidant activity. The results revealed that all the three contained alkaloids, carbohydrates, flavonoids, tannins, anthocyanins, steroids and phenols. Saponins were absent in all the three extracts. Sida cardifoli...
Ayurveda, an ancient system of medicine explains well about joint disorders like vatarakta, sandhivata, amavata etc. Among these, amavata is a disease which is caused due to hypo-functioning of digestive fire. Rheumatoid arthritis is the disease which keeps clinical similarity with amavata. Ama is main pathogenic factor in the disease amavata. Factors causing formation of ama have direct impact on...