Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
EVALUATION OF ANTIOBESITY EFFECT OF GYMNEMA SYLVESTRE AND ACORUS CALAMUS ON DIET INDUCED MODEL OF OBESITY IN RATS
Introduction: Obesity is a morbid condition characterized by abnormal or excess deposition of body fat to an extent that it adversely affects health. The basic etiology behind obesity is the disparity between the energy intake and energy expenditure. Lifestyle modifications and drug treatment is the mainstay of treatment. Unfortunately the benefits are for short term that might be because of cessa...
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1439
IN VITRO EFFECT OF SOME IRANIAN MEDICINAL PLANTS ON THE HISTOMONAS MELEAGRIDIS PARASITE
Objective: This study aimed to investigate the in vitro effect of the extracts of five Iranian medicinal herbs on Histomonas meleagridis protozoan parasite. Methods: This study was conducted in the following three phases in Khorramabad, Iran, in 2016: 1) preparing and extracting the 5 medicinal herbs Dracocephalum kotschyi, Satureja khuzestanica, Pulicaria gnaphalodes, Olea europaea, and Echinopho...
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1594
A COMPARISON STUDY OF GRANULE AND DRY POWDER PROPERTIES OF CO-PROCESSED LACTOSE MONOHYDRATE AND CELLULOSE EXCIPIENTS USING THERMAL AND RHEOLOGICAL TECHNIQUES WITH WATER AS THE BINDER
Poor flow and cohesion are the most common problems encountered during manufacturing of a tablet. Tablets are produced by compression of formulation ingredients including the drug and excipients that improve processing properties of the product. Excipients may include fillers, diluents, binders, lubricants etc. which are added to impart good flow. Cellulose and Lactose have been widely used in Pha...
6554
2207
MICROWAVE – ASSISTED EXTRACTION OF FLAVONOIDS AND PROFILING FLAVONOID CYTOTOXICITY AGAINST Hep-G2 HUMAN CANCER CELL LINE
Hepatic cancer is one of the most causes for cancer death in the world. The aim of this work was to compare and survey the cytotoxic activity of a group of differently classed flavonoids and three plant extracts known for their high antioxidant activities against Hep-G2 human cancer cell line. Also to isolate some flavonoids from the plant extracts using easier, modified methods of higher yield an...
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2346
IN SILICO AND IN VITRO XANTHINE OXIDASE INHIBITORY ACTIVITY OF EMBILICA OFFICINALIS (AMLA)
The present study on Embilica officinalis, a common household remedy and the present study describes the inhibition of enzyme xanthine oxidase (XO) with in vitro analyses and assenting in silico study to produce an effective phytoconstituents. The results explained the ethanolic extract of Embilica officinalis (EOEt) exhibited antioxidant and defensive oxidative stress and allied with its total ph...
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1726
QUALITY CONTROL OF PYRAZINAMIDE IN FORMULATION USING MICELLAR LIQUID CHROMATOGRAPHY
Pyrazinamide is an important anti-tubercular drug which shortens the course of TB chemotherapy. A direct injection liquid chromatographic method is developed for the determination of pyrazinamide in pharmaceutical formulation. The method includes a micellar mobile phase containing 0.15M sodium dodecyl sulphate and 1% butanol (v/v) buffered at pH3, a Princeton SPHER-100 C18 column (250mm × 4.6mm, ...
4589
1769
ANTIDIABETIC ACTIVITY OF METHANOLIC LEAVES EXTRACTS OF TRANSFORMED SOYBEAN IN 3T3-L1 PRE-ADIPOCYTES CELL LINE
The present study was initiated to quantify the Isoflavones content that accumulated in soybean transgenics with RnPPARγ gene by using high performance liquid chromatography. The effects of methanolic leaves extract of transformed soybean in 3T3-L1 adipocyte cell line. The RnPPARγ transgenic soybean variety JS335 was developed and transgenics were confirmed by PCR and Southern blot techniques. T...
4109
1502
ANTI-BIOFILM ACTIVITY OF MIXED ‘TRANSITION METAL (Mn, Fe, Co, Ni, Cu AND Zn) – CALCIUM TARTARATE’ COMPLEXES
A series of six new, mixed transition metal and alkaline earth metal complexes of the general formulation [MM/(C4H4O6)2.xH2O] (where M= Mn, Fe, Co, Ni, Cu and Zn, M/ = Ca ) are synthesized by using bidentate tartarate ligand and are characterized by different analytical techniques such as elemental analysis, TGA, FTIR, XRD, SEM, magnetic susceptibility study, UV-visible spectroscopy etc. All synth...
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1439
TARGETING INFLAMMATORY PROTEINS USING IMMUNOMODULATOR FOR REGULATION OF HEPATOCELLULAR CARCINOMA MICROENVIRONMENT
Inflammation plays fundamental role in hepatocellular carcinoma (HCC) initiation, progression and metastasis. The over expression of pro-inflammatory factors like Tumor necrosis factor-α (TNF-α), selectin, (IL)-6, nuclear factor-κB, TGF-β can alter the hepatic microvasculature. Natural products such as polyphenols, alkaloids, flavonoids, and flavonols have the ability to interface microenviron...
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1591
SOLID DISPERSION OF ORAL CANDESARTAN CILEXETIL TABLETS FOR HYPERTENSION: DEVELOPMENT AND CHARACTERISATION
The main aim of this study was to prepare solid dispersion of Candesartan cilexetil so as to improve its solubility and dissolution characteristics in order to enhance its oral bioavailability. Solid dispersion was formed by fusion method. 9 formulations (F1-F9) were prepared using different carriers i.e. Sorbitol, Polyethylene Glycol (PEG 6000) and Poloxamer 407 at different ratios of 1:1, 1:3, 1...
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