Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
VALIDATION AND CHARACTERIZATION OF NANOPARTICLES AUNPS AND AUNPS-LAN CONJUGATE FOR CAPILLARY ELECTROPHORESIS
The Ooctapéptido (LAN: 3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide (2 → 7) disulphide acetate, angiopeptin acetate) cyclic covered gold nanoparticles (AuNPs) results in a complex (AuNPs-LAN) when reacted following the aqueous synthesis using Turkevich method for preparing colloidal gold nanoparticles followed by reaction of conjugat...
5456
1795
OPTIMIZATION OF INFLUENZA A AND B VIRUSES CULTIVATION CONDITIONS FOR PREPARATION OF TRIVALENT SEASONAL INFLUENZA SPLIT VACCINE
This article presents the results of studies on determination of optimal parameters of recombinant strains A/NYMC X-217 (H3N2) and B/NYMC BX-49 of influenza virus cultivation in chicken embryos. It is found that a maximum virus accumulation is formed under the following cultivation conditions: age of chicken embryos is 9-11 days in case of inoculation of the allantoic cavity, inoculated virus dose...
3484
1076
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NEW BAYLIS-HILLMAN DERIVED NITRO METHYLENE IMIDAZOLE DERIVATIVES AS INSECTICIDAL AGENTS
A series of Baylis-Hillman derived N-cinnamyl substituted nitro methylene imidazole derivatives 4a-swere synthesizedfrom Baylis-Hillman acetates and nitro methylene imidazole compoundsand characterised by 1H NMR, IR, Mass and HRMS spectroscopy. Their insecticidal activities were evaluated against T. Castaneum and compared with a standard insecticide Permethrane. Preliminary biological activity tes...
3299
1723
VALIDATED HPTLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF EMTRICITABINE AND TENOFOVIR IN DRUG FORMULATION
A simple, precise, specific and accurate high-performance thin-layer chromatographic method has been developed for the simultaneous determination of Emtricitabine (EMB) and Tenofovir (TEN) in pharmaceutical dosage form. The separation was carried out on Merck HPTLC aluminum plates of silica gel 60 F254, (20×10 cm) with 250 μm thickness using toluene: ethylacetate: methanol in the ratio (2:8:1 v/...
3430
1161
STUDY OF ANTIDEPRESSANT ACTIVITY OF CHRONIC ADMINISTRATION OF TRAMADOL AND WHEN IT IS CO-ADMINISTERED WITH FLUOXETINE IN LOW DOSES IN SWISS ALBINO MICE USING DESPAIR SWIM TEST
Objective: To evaluate the antidepressant activity of chronic administration of Tramadol alone and when combined with Fluoxetine in low doses in albino mice. Methods: The antidepressant effect was determined by recording the immobility time in Despair Swim Test. The mice were randomized into seven groups, with six mice in each group. Group 1 mice were given normal saline (10 ml/kg) which served as...
3209
1110
WOUND HEALING ACTIVITIES OF FICUS RACEMOSA LEAVES ETHANOLIC EXTRACT ON EXCISION WOUND MODEL OF WISTAR ALBINO RATS
Present study describes wound healing activities of Ficus racemosa (Linn.) leaves extract on excision wound model of wistar albino rats. During the study, fresh plant materials after shade drying was used for the isolation of extract using soxhlet apparatus and percentage yield was obtained (3.50% in ethanol). Then, preliminary phytochemical screening of the extract was done and certain secondary ...
4390
1772
NEUROPHARMACOLOGY OF DEPRESSION: A REVIEW
The selected theories are based on studies investigating the possible role of stress hormones and cytokine; gamma-aminobutyric acid (GABA); glutamate; monoaminergic transmitters such as serotonin, norepinephrine, dopamine; omega-3 fatty acid; T-cell; β-endorphine; synaptic plasticity; endocrine system and endocannabinoids in the pathophysiology of depression. Because all theories of depression ap...
5791
1817
METHOD DEVELOPMENT AND VALIDATION OF ZOPICLONE IN BULK AND TABLET DOSAGE FORM USING RP-HPLC
Zopiclone belongs to a class of medicines commonly called Z-drugs. It is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. A Reverse Phase High Performance Liquid Chromatography method was developed and validated for the quantification of zopiclone in bulk and tablet dosage form. Chromatography was achieved using a Wa...
4988
1827
EFFECTS OF CADMIUM STRESS ON ANTIOXIDANT ENZYMES IN VIGNA RADIATA ROOTS
A brief study to analyze oxidative stress and antioxidant response of cadmium stress was carried out. The plant chosen Vigna radiata (var. SML-668) was hydroponically grown in 0, 50µM, 100µM and 150µM, cadmium chloride. The roots were taken from hydroponic culture at 6 days of growth for various enzymatic and metabolic estimations. Among the antioxidant enzymes, root catalase and ascorbate pe...
3482
1176
SPECTROPHOTOMETRIC DETERMINATION OF CARISOPRODOL IN PURE AND PHARMACEUTICAL FORMS USING TRIPHENYL METHANE DYES
New simple and sensitive extractive spectrophotometric methods have been developed and described for the determination of carisoprodol in pure form and in pharmaceutical formulations. The developed methods involve formation of coloured chloroform extractable ion-pair complexes of carisoprodol with triphenyl methane dyes viz., bromocresol green (BCG), bromothymol blue (BTB) and bromophenol blue (BP...
4035
1946