FORMULATION AND EVALUATION OF COLON TARGETED DRUG DELIVERY SYSTEM OF FLURBIPROFEN FOR TREATMENT OF RHEUMATOID ARTHRITIS
In this present research work, the aim was to develop ileo-colonic targeted mini-tablets filled capsule system of flurbiprofen for treatment of rheumatoid arthritis. In the present study pH independent colon targeted system was developed and evaluated. SMEDDs of poorly water soluble drug flurbiprofen were prepared to enhance its dissolution rate and bioavailability. Mini-tablets of flurbiprofen we...
BROAD SPECTRUM ANTIBIOFILM AND ANTIQUORUM SENSING POTENTIAL OF CRUDE SECONDARY METABOLITE EXTRACTS OF MICROBIAL ISOLATES OBTAINED FROM POLLUTED WALDHUNI RIVER
Bacterial biofilms due to antibacterial resistance are causing serious health issues with respect to infection control, its prognosis and treatment of disease. The current scenario demands need of new and alternative antibacterial compounds for treatment of such infections. The current study highlights the use of polluted river, Waldhuni, as a source of potent microorganisms with antibiofilm prope...
Introduction: Glaucoma valves have been used in the treatment of glaucoma in the cases where medications no longer show the appropriate results. Due to the various complications in molteno, other glaucoma valves such as Ahmed glaucoma valve (AGV) were introduced. Ahmed glaucoma valve has proved to be very useful in the management of glaucoma. This review thus summarizes how far AGV has been succes...
The mineral Srotonjana (antimony sulfide) is being used by Indians since ancient times. In Ayurvedic texts, it has been directed that Srotonjana should be used only after shodhana. Shodhana is a process to remove the unwanted physical, chemical impurities and toxic material and makes it suitable for medicinal use. Metallography is an advanced scientific study which is used in the study of the micr...
KNOWLEDGE AND ATTITUDE OF PRIMARY CARE PHYSICIANS TOWARD USE OF HERBS AS MEDICINE IN AL-WAZARAT HEALTH CENTER, PRINCE SULTAN MILITARY MEDICAL CITY, RIYADH, SAUDI ARABIA
Introduction: Herbs are the second most commonly used form of complementary and alternative medicine by public. The uses of medicinal herbs continue to increase worldwide. However, clinicians generally have limited knowledge and confidence about using of herbs in medicine. Therefore, this research aimed to assess the level of knowledge and attitude of primary care physicians toward use of medicina...
DEVELOPING A TOOL FOR MEASURING KNOWLEDGE ABSORPTIVE CAPACITY AND ASSESSING ITS EFFECT ON INNOVATION PERFORMANCE OF IRANIAN PHARMACEUTICAL COMPANIES
Now a day’s establishing and sustaining competitive advantage depends on the effective development of Knowledge Absorptive Capacity (KAC) and innovations. This study evaluated the role of prior technical experiences in developing firm’s absorptive capacity and the contribution of this type of capacity to the firm’s innovation performance. In this study we designed a questionnaire to assess f...
ASSESSING THE GENOTOXIC AND CYTOTOXIC RESPONSES OF THE H-29 CANCER CELL LINES ON THE ETHANOLIC EXTRACTS OF THE OYSTER MUSHROOM, PLEUROTUS OSTREATUS VAR. FLORIDA
Globally, colorectal cancer is the third most common known today. Lack of cheap, rapid, safe and reliable cancer treatments resulted to the continued pursuit to find natural sources of bioactive compounds that can be cytotoxic or damaging to the DNA of cancer cells. One of the potential resource is the edible oyster mushroom (Pleurotus ostreatus var Florida) reported to have medicinal properties. ...
Terminalia catappa Linn. belongs to the family Combretraceae found in tropical regions of Asia, Africa and Australia, which is commonly called as Indian almond, sea-almond, tropical almond, wild badam. The fruit is useful in bronchitis and bowels. Juice of leaves is used in the preparation of the ointment for scabies, leprosy, cutaneous diseases and also as analgesic. The root bark is used in dyse...
Medicinal plants and natural products have many applications in the treatment of viral diseases, due to much lower side effects. Different types of hepatitis, especially hepatitis B, are of the viral diseases whose treatment using herbal medicines is currently of great interest due to the limited availability of effective chemical drugs and having numerous side effects. Due to the attention paid t...
Bisphenol-A (BPA) is a chemical produced in large volumes worldwide and has large market diffusion in many consumer products. BPA is used mainly as a monomer in the production of polycarbonate plastics and as a precursor of epoxy resins. So the present study was undertaken to examine the toxic effect of BPA on heart function in pregnant rat models. BPA (50 mg/kg.b.wt/day and 500 mg/kg.b.wt/day) wa...