Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
IN VITRO EFFECT OF SOME IRANIAN MEDICINAL PLANTS ON THE HISTOMONAS MELEAGRIDIS PARASITE
Objective: This study aimed to investigate the in vitro effect of the extracts of five Iranian medicinal herbs on Histomonas meleagridis protozoan parasite. Methods: This study was conducted in the following three phases in Khorramabad, Iran, in 2016: 1) preparing and extracting the 5 medicinal herbs Dracocephalum kotschyi, Satureja khuzestanica, Pulicaria gnaphalodes, Olea europaea, and Echinopho...
2574
960
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SUBSTITUTED N-(3-FORMYL-4-OXO-4H-CHROMEN-2-YL)-N- PHENYLBENZENESULFONAMIDE AND ITS DERIVATIVES
Modification of a drug molecule of a series having optimal activity is widely used and continues to be an important factor necessary for new drug discovery. Infectious diseases which increase dramatically by resistant and multi resistant microbes are now a days the second major cause of death worldwide and the third leading cause of death in the developed countries. Although, the search for new le...
2538
931
A COMPARISON STUDY OF GRANULE AND DRY POWDER PROPERTIES OF CO-PROCESSED LACTOSE MONOHYDRATE AND CELLULOSE EXCIPIENTS USING THERMAL AND RHEOLOGICAL TECHNIQUES WITH WATER AS THE BINDER
Poor flow and cohesion are the most common problems encountered during manufacturing of a tablet. Tablets are produced by compression of formulation ingredients including the drug and excipients that improve processing properties of the product. Excipients may include fillers, diluents, binders, lubricants etc. which are added to impart good flow. Cellulose and Lactose have been widely used in Pha...
4828
1547
PROTECTIVE EFFECTS OF FERULIC ACID AGAINST LIVER CHOLESTASIS INDUCED BY ETHINYLESTRADIOL IN ADULT FEMALE RATS
The aim of the present article was to examine the protective effect of ferulic acid against liver cholestasis in female rats treated with ethinylestradiol (EE). The daily oral administration of the ferulic acid at a concentration of 40 mg/kg body weight for 15 days to rats treated with EE (100 µg/kg body weight for 5 days) resulted in a significant protection against EE-induced decrease in plasma...
3310
1260
THE EFFECTIVE ROLE OF URSOLIC ACID AND OCIMUM SANCTUM (LINN.) LEAF EXTRACT ON SOME MARKER CARBOHYDRATE METABOLITES IN MALE ALBINO RATS
Ursolic acid is a pentacyclic triterpinoid compound, the major constituents of the Tulsi leaves, has been suggested to possess anti-fertility effect in rats of both sexes. This study has attempted to investigate the anti-fertility potentials of Ocimum sanctum leaf extract and ursolic acid in male albino rats. Three groups of male albino rats were taken, first group as control, second group were ad...
4476
1145
PARTIAL PURIFICATION AND CHARACTERIZATION OF 3-CYANOPRIDINASE RESPONSIBLE FOR PRODUCTION OF NICOTINIC ACID
A thermostable bacterial 3-cyanopyridinase enzyme has been identified that catalyze 3-cyanopyridine to nicotinic acid and ammonia. Nicotinic acid is mainly used in food, pharmaceutical and biochemical industries. This study was undertaken to optimize the purification of 3-cyanopyridinase enzyme and characterization of its various kinetic properties. The partial purification of enzyme has been carr...
2551
881
FORMULATION AND OPTIMIZATION OF LIQUISOLID TABLETS OF OLMESARTAN MEDOXOMIL USING 32 FACTORIAL DESIGN
Olmesartan medoxomil, a BCS class II drug, is an angiotensin-II receptor antagonist used for the treatment of hypertension. A liquisolid tablet of Olmesartan medoxomil was developed to improve its dissolution and flow properties. The commonly used carrier Avicel was compared with Neusilin. Because of higher liquid load factor, Neusilin was selected as a carrier for further optimization study using...
3707
1210
ANTIDIABETIC ACTIVITY OF METHANOLIC LEAVES EXTRACTS OF TRANSFORMED SOYBEAN IN 3T3-L1 PRE-ADIPOCYTES CELL LINE
The present study was initiated to quantify the Isoflavones content that accumulated in soybean transgenics with RnPPARγ gene by using high performance liquid chromatography. The effects of methanolic leaves extract of transformed soybean in 3T3-L1 adipocyte cell line. The RnPPARγ transgenic soybean variety JS335 was developed and transgenics were confirmed by PCR and Southern blot techniques. T...
3094
961
GLYCINE AND GOLD NANOPARTICLES FOR THE ELECTROCHEMICAL DETERMINATION OF AN ANTI-PARKINSON’S DRUG IN A TERTIARY MIXTURE
A sensitive sensor for the electrochemical determination of anti-Parkinson’s disease drug; entacapone (EN) was constructed using carbon paste electrode modified via electro-polymerization of glycine (GL) incorporate gold nanoparticles (GNP) and sodium dodecyl sulphate (SDS). Different voltammetric techniques, electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM) te...
2769
1022
VARIOUS SCORES USED FOR PROGRESSION OF LIVER DISEASE
Multiple causes of liver diseases that will affect the health related quality of life and are dispersed globally. It is difficult to diagnose the different stages of liver disease. Scores like Child Pugh Score(CPS), Model For End Stage Liver Disease(MELD), Monoethylglycinexylidine(MEGX), Von willibrand factor (vWF) etc are used to detect the progression of liver disease like hepatitis, cirrhosis, ...
2879
871