Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ANALGESIC, ANTIINFLAMMATORY AND ANTIPYRETIC ACTIVITY OF TRICHOSANTHES DIOICA ROXB. LEAF EXTRACTS
Aim of the study: This study evaluates the analgesic, anti-inflammatory and antipyretic activities of the aqueous, methanol and n-hexane extracts of Trichosanthes dioica Roxb. to provide experimental evidence for its traditional use such as fever, pain and inflammation. Materials and methods: Investigations on the analgesic effects of Trichosanthes dioica Roxb. was carried out by acetic acid-induc...
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PHYTOCHEMICAL PHARMACOGNOSTICAL ANTIMICROBIAL AND CYTOTOXICITY STUDIES ON CANTHIUM COROMANDELICUM FRUIT
The medicinal plants are the key source in the life of human beings. The present study was aimed to evaluate the preliminary phytochemistry, pharmacognostical and antimicrobial activity of Canthium coromandelicum fruit. The fruit showed the presence of secondary metabolites like flavonoids, steroids, tannins, phenol, sterols, cardiac glycoside and saponin glycoside in various extracts. The pharmac...
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FORMULATION DEVELOPMENT AND EVALUATION OF CLOPIDOGREL BISULFATE TRANSDERMAL PATCHES
Clopidogrel bisulphate is a drug used in inhibiting the platelet aggregation and also used in the treatment of cardiovascular disorders. It acts by inhibiting the adenosine diphosphate and is almost absorbed (98%) after oral administration. Approximately 50 % of drug is excreted in urine and 40% in feces. The plasma half life of drug is about 8 hours which makes frequent dosing necessary to mainta...
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SCOPE AND EVALUATION OF SAPODILLA PECTIN IN PHARMACEUTICAL SOLID AND LIQUID ORALS WITH ESPECIAL REFERENCE TO ITS EFFECT ON VARIOUS PHYSICO-MECHANICAL PROPERTIES UPON BOTH SOLID AND LIQUID DOSAGE FORM
The aim of this study was to understand and study the role and effect of different concentration of sapodilla pectin as a binding agent in tablet formulations and also its on the effect on physical evaluation of suspension. For this purpose two model drugs paracetamol and ibuprofen were selected and granules were made by wet granulation using different concentration of pectin. The tablets were fir...
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RP-HPLC METHOD FOR THE SIMULTANEOUS ASSAY OF METFORMIN AND BENFOTIAMINE: DEVELOPMENT AND VALIDATION
A sensitive, precise and accurate reverse phase high performance liquid chromatographic method (RP-HPLC) using an isocratic elution of 0.1 M NaH2PO4 (pH 3.0) and acetonitrile (80:20 v/v) with a flow rate of 1.0 mL/min, a column temperature of 30 °C and UV detection at 254 nm was developed for the estimation of metformin and benfotiamine simultaneously. The method was validated following guideline...
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BIOCHEMICAL ANALYSIS IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER IN JAMMU POPULATION
The study was conducted to study biochemical parameters in 42 major depressive disorder (MDD) patients, 22 males and 20 females (age range 18 - 55 years) visiting the Psychiatric Department, Government Medical College, Jammu. The smoking and alcohol intake was much lower (95.24% and 88.09%) in patients (both male and female) diagnosed with MDD. The well being status is also 76.19% satisfactory wit...
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MITOCHONDRIA – TARGETED ANTIOXIDANT: AGING
The mitochondrion, the “power house of cell”, plays a central role in energy-generating processes so called as ‘‘master of life and death’’. A decline in mitochondrial function plays a key role in the aging process and increases the incidence of age-related disorders. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and ...
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DESIGN AND EVALUATION OF CHITOSAN-BASED MICROPARTICLES AS MODELS OF PROTEIN DELIVERY SYSTEMS
Controlled release systems for protein and peptide vaccines based polymers have been considered for many applications in medical therapies. Chitosan is non-toxic and easily absorbed biopolymers and is often used in many researches to sustained release drugs and proteic vaccines. This study investigates the kinetics of release in vitro of bovine serum albumin (BSA) from chitosan microparticles and ...
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SYNTHESIS OF BENZO[G]QUINOXALINE-5,10-DIONE BASED PYRAZOLINE DERIVATIVES AND THEIR ANTIMYCOBACTERIAL ACTIVITY
Eleven new compounds belonging to series 7-[5-(substituted) phenyl - 4, 5-dihydro-1H-pyrazol-3-yl]-2,3-diphenyl-5H, 10H - benzo[g] quinoxaline - 5, 10 - dione (Compound 7a-k) were synthesized by multistep synthetic scheme. The newly synthesized compounds were screened for their in-vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv by L.J. Slope (Conventional) Method. Compo...
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BISPHENOL A ENHANCES GROWTH OF Hep-G2 CANCER CELLS BY UPREGULATING EXPRESSION OF PRO – INFLAMMATORY AND PRO – ANGIOGENESIS PROTEINS
Bisphenol A (BPA) is primarily used in the manufacture of plastics and resins. There are many scientific reports that point to the adverse effects of this chemical to different animal models. There has been an increase in use of plastic during the last couple of decades and this has increased human exposure to plasticizers like Bisphenol A. But since little is known on how these endocrine disrupto...
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