Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
FORMULATION AND EVALUATION OF HYDRALAZINE HYDROCHLORIDE MOUTH DISSOLVING TABLET FOR THE MANAGEMENT OF ECLAMPSIA AND PRE-ECLAMPSIA
Eclampsia and Pre-Eclampsia is an acute and life-threatening complication during pregnancy. Hydralazine hydrochloride is one of the drugs of choice in treating this condition. The purpose of the present research work was to formulate the Mouth Dissolving Tablets by using different methods and provide a suitable patient convenience dosage form to enhance the bioavailability and provide quick onset ...
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PHYTOCHEMICAL INVESTIGATION AND HEPATOPROTECTIVE EFFECT OF SCOPARIA DULCIS AGAINST CARBON TETRACHLORIDE INDUCED LIVER DAMAGE IN RATS
The objective of the present study is to carry out the photochemical investigation and hepatoprotective activity study of different extracts of Scoparia dulcis. Scoparia dulcis Linn. belongs to the family Scrophulariaceae and have ruminate medicinal properties. The different extracts of this plant were prepared by successive extraction with petroleum ether, chloroform and ethanol. These extracts (...
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STATISTICAL OPTIMIZATION FOR DEVELOPMENT OF COLON TARGETED pH DEPENDANT METRONIDAZOLE GRANULES USING FULL FACTORIAL DESIGN
The objective of this study was to evaluate and optimize Eudragit concentration and coating level on metronidazole release from granules for colon delivery using 32 full factorial design. Independent variables selected were Eudragit conc. (10, 15 and 20%) and coating level (10, 15 and 20%), the evaluated responses were percent drug release at 5 h, 24 h and time to release 50% of the drug. The diss...
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EFFECT OF CLASSICAL HERBO – MINERAL SIDDHA FORMULATION AGASTHIYAR KUZHAMBU FUMIGATION THERAPY ON SILAIPUN (VARICOSE ULCER) – A CASE STUDY
Siddha system is one of the ancient systems of medicine. In this system the herbals, metals, minerals and animal products has been used to prepare the medicines for treating various illness. Siddha medicines are divided into internal medicines and external medicines, in which Pugai maruthuvam (Fumigation therapy) is one of the external therapies. Agasthiyar Kuzhambu is one of the classical herbo m...
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STUDY OF MICROBIAL DIVERSITY IN ULVA LACTUCA FROM NORTH WEST COAST OF GUJARAT, INDIA
Seaweeds form economically important component of marine ecosystems worldwide. A wide range of beneficial and detrimental interactions exists between seaweeds and epiphytic as well as endophytic bacteria. Diversity study can be used to retrieve ecological information about community partner that relates the degree of stability of that community. The present work deals with the study the microbial ...
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AQUEOUS EXTRACT OF CENTELLA ASIATICA AS A POTENTIAL ANTI-KELOID AGENT
Centella asiatica (CA) is a reputed medicinal plant that has been shown to have pharmacological effect on skin wound healing. The aim of the study was done to assess the effects of aqueous extract of CA on human dermal fibroblasts in an in vitro model of wound healing. Dermal fibroblasts were cultured with or without supplementation of aqueous extract of CA. Viability and proliferation of the fibr...
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CHARACTERIZATION OF ANDROGRAPHOLIDE IN INCLUSION COMPLEX USING BETA CYCLODEXTRIN
Andrographolide (AG) is a purified isolate of chemical synthesis resulted from sambiloto herbs (Andrographis paniculata Nees.), which has various pharmacological actions such as anti-inflammatory, hepatoprotector, antidiabetic, inhibition of replication of the HIV virus, antimalarial, anti-arthritic, anti-hyperlipidemic, anticancer, antimicrobial, immunomodulator and antiparasitic. To enhance the ...
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COMPARATIVE ANALYSIS OF CHEMICAL AND PHYTOCHEMICAL COMPOSITIONS OF FOUR SELECTED MEDICINAL PLANTS AND EVALUATION OF ANTIDIABETIC PROPERTIES OF AQUEOUS EXTRACTS OF TRIGONELLA FOENUM-GRAECUM AND COMBINATION OF TRIGONELLA FOENUM-GRAECUM – MOMORDICA CHARANTIA
The present study was designed to compare the chemical and phytochemical compositions of Momordica charantia, Azadira chtaindica, Trigonella foenum-graecum and Phyllanthus emblica and subsequently, antidiabetic activities of T. foenum-graecum and a combination of polyherbal extract of T. foenum-graecum and M. charantia were evaluated on alloxan induced diabetic mice. The proximate and phytochemica...
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PHARMACOLOGICAL EVALUATION OF SOME NOVEL THIENO 1, 2, 3-TRIAZINES-4-ONES FOR ITS ANALGESIC ACTIVITY
The analgesic activity was assessed using hot plate method, formalin induced paw licking test, acetic acid induced writhing test. Preliminary investigations were carried out with water, DMSO and chloroform for solubility. For analgesic activity 1, 2, 3- triazine-4-ones series of compounds CP1, CP2, CP3 showed significant increase in jumping time of mice in hot plate method at only higher dose leve...
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LAYER BY LAYER ASSEMBLY ON THE SURFACE OF NANOPARTICLE FOR CHEMOTHERAPEUTIC DRUG LOADING
In the present investigation, fluorescently labelled sulfated polystyrene beads were coated with oppositely charged polyelectrolytes {i.e. Poly diallyl dimethyl ammonium chloride, Poly (sodium 4-styrene sulfonate)} through an electrostatic interaction by using layer by layer assembly method. Doxorubicin is a model anticancer drug with protonatable amine group that acquires net positive charge in a...
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