Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PHYTOCHEMICAL STUDIES AND IN VITRO ANTIOXIDANT POTENTIAL OF TWO DIFFERENT EXTRACTS OF CRINUM JAGUS
The antioxidant potential of the aqueous and hydro/ethanolic (ethanol/water) extracts of Crinum jagus were explored considering their total phenolic, flavonoid and proanthocyan contents, 1.1-Diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, ferrous ions chelating ability and nitric oxide radical inhibiting activity. Hydroethanolic extract has exhibited the highest total polyphenol...
3715
1471
SOLID DISPERSION ADSORBATE–A NOVEL TECHNIQUE FOR DISSOLUTION ENHANCEMENT OF FEBUXOSTAT
The objective of the present investigation was to improve dissolution characteristics of febuxostat, a BCS class – II drug, by formulating it as solid dispersion adsorbate. Solid dispersion adsorbate(SDA) was prepared using labrasol, transcutol and lutrol F127 as carriers and neusilin as adsorbent. Formulation was prepared using combination of melt and adsorption technique. Optimized formulation...
4617
2254
HPTLC FINGERPRINTING, ANTIOXIDANT POTENTIAL AND ANTIMICROBIAL EFFICACY OF INDIAN HIMALAYAN LINGZHI: GANODERMA LUCIDUM
Ganoderma lucidum (Fr.) Karst., known as medicinal mushroom and it contains several bioactive phytochemicals such as polysaccharides, nucleosides, alkaloids, coumarin, ergosterols, ganoderic acids, lactones, mannitol, organic germanium, triterpenoids, unsaturated fatty acids, vitamins and minerals which are well known for their pharmacological properties. In the present investigation adenine, aden...
4581
1318
SURVEY ON PATTERN OF SNAKE BITE CASES ADMITTED IN SOUTH INDIAN TERTIARY CARE HOSPITALS
Background: Snake bite is a problem across the developing countries, where agriculture is one of the main sources of income and India is one among it. Objective: The study was carried out to determine the pattern of snake bite in four different selected tertiary care hospitals of south India for a period of 03 years from March 2011 to March 2014. Material and Methods: A prospective observational s...
4063
1474
A REVIEW ON POLYMER DRUG CONJUGATE – WHAT, WHY AND HOW?
It is well known that polymeric prodrug or polymer-drug conjugate is an effective and fast growing technique for improved use of drugs for therapeutic applications. Polymer conjugated drugs generally exhibit prolonged half-life, higher stability, water solubility, lower immunogenicity and antigenicity and specific targeting to tissues or cells. Polymers are used as carriers in polymeric prodrugs/m...
6066
1479
SPECIFIC TARGETING OF FOLATE RECEPTOR BY METHOTREXATE CONJUGATED MODIFIED MAGNETIC NANOPARTICLES: ENZYMATIC RELEASE AND CYTOTOXIC STUDY
Magnetic nanocarriers have been used for specific drug delivery to release therapeutic drugs into target cancer cells. We used bifunctional methotrexate (MTX) conjugated magnetic nanoparticles (MNPs) (~37 nm) engineered by dopamine–polyethylene glycol to targeted folate receptor (FR)-positive cancer cells. For this purpose, MTX was chemically loaded on to MNPs with N, N-dicyclohexylcarbodiimide ...
4186
1830
IN-SILICO APPROACH FOR THE ASSESSMENT OF ORAL CANCER PROPERTY ON LIMONIA ACIDISSIMA
Cancer is the abandoned growth of cells that invade and cause damage to surrounding tissue. Oral cancer appears as a growth or uncomfortable in the mouth that does not go away. Oral cancer, which includes cancers of the lips, tongue, cheeks, floor of the mouth, hard and soft palate, sinuses, and pharynx (throat). Tabocco and alcohol are recognized as the foremost risk factor for this oral cancer. ...
3873
2010
RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF IMPURITIES FROM EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE TABLET
Stability indicating RP-HPLC gradient method developed for simultaneous determination of impurities and degradation products from Emtricitabine and Tenofovir Disoproxil Fumarate in pharmaceutical tablet dosage form. The chromatographic separation was achieved by using column ACE C18 (250 x 4.6, 5μ). The mobile phase-A consists of 0.01M potassium dihydrogen phosphate buffer with pH 4.0 adjusted us...
31643
1953
ANTIOXIDANT ACTIVITY OF LEAF AND FRUIT EXTRACTS OF RAUWOLFIA TETRAPHYLLA LINN.
Four crude extracts viz, methanol extract of fruit and n-hexane, dichloromethane, methanol extracts of the leaf of R. tetraphylla were investigated for in vitro antioxidant activity at different concentrations (5, 50 and 100 μg). Antioxidant ability is expressed as equivalents of ascorbic acid and was calculated using standard graph. The results indicated that the leaf n-hexane and methanol extra...
4280
1171
EFFECTIVENESS OF ANTI-INFLAMMATORY PLASTER FROM KENCUR (KAEMPFERIA GALANGA L.) RHIZOME ETHANOL EXTRACT
Kencur (Kaempferia galanga L.) is a plant of Zingiberaceae family. Some studies have shown that kencur can reduce inflammation because flavonoid kaempferol which is contained in kencur has anti-inflammatory activity. Optimized the use of the rhizome kencur, research was conducted on anti-inflammatory plaster containing kencur rhizome extract and its effectiveness for treating inflammation. The stu...
5550
2045