Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
ANTIMICROBIAL ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF IMPATIENS BALSAMINA SEED (KACI-T-TUMPAI) COLLECTED FROM COIMBATORE DISTRICT, TAMIL NADU, INDIA
The antimicrobial effects of I. balsamina seed hexane extract against Staphylococcus aureus, Klebsiella pneumonia, Proteus vulgaris, and Serratia marcescens were determined using the standard technique. As well as the phytochemical properties of the extract on the test isolates were also examined using the standard methods. The phytochemical components of the hexane extract of the I.balsamina seed...
5785
1939
INVESTIGATION OF BIOACTIVE COMPOUNDS AND ANTIOXIDANT ACTIVITY OF EXCOECARIA AGALLOCHA, L.
Mangrove survives in the most hostile environment with fluctuating tidal and saline regime. The present work focused on a detailed study on quantitative estimation of phytoconstituents and DPPH radical scavenging activity of Excoecaria agallocha L., a mangrove from Kattiparambu and Chirackal of Ernakulam District, Kerala. Preliminary phytochemical investigation indicated the presence of biological...
5195
1751
EFFICACY AND MECHANISMS OF MEDICINAL PLANTS AS IMMUNOTHERAPY IN TREATMENT OF ALLERGIC RHINITIS: A SYSTEMATIC REVIEW
Allergic rhinitis is a common disease of immune system that negatively affects general health, quality of life, and social relationships. In the recent years, many studies have been conducted to discover novel treatments for this disease particularly using natural products. Here, we review findings of recent studies that harness medicinal plants and phyto-therapies in oriental medicine that have e...
8302
2639
PHYSICOCHEMICAL, PHYTOCHEMICAL PROFILING AND ANTI-MICROBIAL ACTIVITY OF PTEROCARPUS MARSUPIUM
Pterocarpus marsupium Roxb. (Fabaceae) is a moderate to large deciduous tree, belonging to family Fabaceae. It is considered as an extremely useful source of unique natural products for development of medicines against various diseases and for industrial product development. The present study includes physicochemical parameters like ash value, extractive value, fluorescence analysis, moisture cont...
5878
2072
POLY (LACTIC-CO-GLYCOLIC ACID) BASED DOUBLE EMULSION NANOPARTICLE AS ACARRIER SYSTEM TO DELIVER GLUTATHIONE SUBLINGUALLY
The sublingual delivery of drugs represents a continuing challenge, as well as an opportunity. In this study, a poly (lactic-co-glycolic acid) (PLGA) based Water-in-Oil-in-Water (w/o/w) double emulsion of nanoparticles was developed as potential platform technology, to generate sustained drug release profile and maximize the bioavailability of the glutathione (GSH). Two-level full factorial design...
3450
1673
SYNTHESIS, ANTITUBERCULAR EVALUATION AND DOCKING STUDIES OF NOVEL BENZIMIDAZOLE ANALOGUES
A series of (Z)-3-((1H-benzo[d]imidazol-2-yl)methyl)-substituted thiazolidine-2,4-dione (9a-n) have been synthesized and evaluated for their mycobacterium inhibitory activity against Mycobacterium tuberculosis H37Rv strain. The structures of the newly synthesized compounds were characterized by FTIR and NMR spectral analysis. Most of the synthesized compounds showed moderate to good anti-tubercula...
3996
1677
DETERMINATION OF PALBOCICLIB IN HUMAN PLASMA USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY – ULTRAVIOLET DETECTION
A simple, sensitive, and high-performance liquid chromatography ultraviolet detection (HPLC-UV) method was developed and validated for the quantification of palbociclib in human plasma. Plasma samples were processed by solid phase extraction using an Oasis hydrophilic-lipophilic balance extraction cartridge (1 mL, 30 mg). Commercial imatinib was used as an internal standard. Palbociclib and imatin...
5928
2369
CUBIC LIQUID CRYSTALLINE NANOPARTICLES (CUBOSOMES): A NOVEL CARRIER FOR DRUG DELIVERY
Lyotropic liquid crystalline systems, such as reversed bicontinuous cubic phases acquire progressive attention because of their unique microstructure and physicochemical properties. Cubosomes were nanostructured liquid crystalline particles, formed from a certain group amphiphilic lipids in definite proportions in water and was stabilized with a triblock copolymer. Substances in use were biocompat...
7278
3222
SAFETY EVALUATION OF GALANGAL (ALPINIA GALANGA) EXTRACT FOR THERAPEUTIC USE AS AN ANTIMICROBIAL AGENT
Hexane extract of Galangal (Alpinia galanga) rhizome was evaluated for acute dermal, oral and intraperitoneal toxicities using OECD guidelines. The undiluted crude galangal extract showed negligible irritation on non-abraded skin of New Zealand white rabbits with 0.25 primary irritation index whereas the abraded skin of the rabbits showed irritation for all tested dilutions of galangal extracts; 0...
6492
2324
BENZOTHIAZOLE DERIVATIVE: A REVIEW ON ITS PHARMACOLOGICAL IMPORTANCE TOWARDS SYNTHESIS OF LEAD
Heterocyclic chemistry plays a very most important role in medicinal chemistry as well as in organic chemistry. Most of the drug molecule formed and possesses therapeutic activity due to the heterocyclic scaffold. A slight change in heterocyclic moiety leads to the major therapeutic change in the drug molecule. Benzothiazole can serve as a unique and versatile moiety for experimental drug design. ...
8336
16252