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AN ANALYTICAL REVIEW OF PLANTS FOR ANTI DIABETIC ACTIVITY WITH THEIR PHYTOCONSTITUENT & MECHANISM OF ACTION
Diabetes and its different types is an age old disease for clinicians since centuries. Many aspects of Diabetes needs to be explored with respect to physiological actions of insulin and the various clinical features of this disease such as tissue complication , since this is life style disease , so proper treatment in relation to diet and anti diabetic agents is emphasized In fact, herbal treatmen...
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TRANSDERMAL PATCHES: PHYSIOCHEMICAL AND IN-VITRO EVALUATION METHODS
Various drugs are available these days, which may either require long term administration via multiple doses or may be susceptible to enzymes and first pass-metabolism or all the above. One way to administer such drugs is through the transdermal route. After a transdermal delivery system is designed, it is important to evaluate it for various essential parameters that help us determine how effec...
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A REVIEW ON PARENTERAL CONTROLLED DRUG DELIVERY SYSTEM
The parenteral administration route is the most effective and common form of delivery for active drug substances with poor bioavailability and the drugs with a narrow therapeutic index. Drug delivery technology that can reduce the total number of injection throughout the drug therapy period will be truly advantageous not only in terms of compliance, but also to improve the quality of the therapy a...
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PREPARATION AND EVALUATION OF PHYTOSOME OF LAWSONE
Lawsonia inermis L. (Lawsone) is reported to contain carbohydrates, proteins, flavonoids and phenolic compounds, alkaloids, terpenoids, coumarins, xanthones and fatty acids. The plant has also been reported to have hepatoprotective, anti-inflammatory, antibacterial, antifungal, antiviral, antioxidant and anticancer properties. Lawsone has low bioavailability because it is less soluble in water and...
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FAST DISSOLVING TABLETS RECENT ADVANTAGES: A REVIEW
Oral drug delivery remains the preferred route of drug delivery. Novel technologies with improved performance, patient compliance, and enhanced quality have emerged in the recent past. The fast dissolving drug delivery system started gaining popularity and acceptance as a new drug delivery system because they are easy to administer and lead to better patient compliance. Fast dissolving drug delive...
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EMERGING TRENDS IN COMPRESSION COATED TABLET DOSAGE FORMS: A REVIEW
Tablets are widely used and most preferred dosage form because of its ease of manufacture and administration, lower cost, good aesthetic appearance. Now a days new trends are going to develop in formulation of conventional tablet in to modified tablet dosage forms like floating, sustained release matrix, coated tablets, controlled release, fast release etc. This review provides the detail informat...
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CONFORMATIONAL ANALYSIS: A REVIEW
Conformational analysis is an important step in molecular modeling as it is necessary to reduce time spent in screening of compounds for activity. Most drugs are flexible molecules with the ability to adopt different conformations by means of rotation about single bonds. Conformations play an important role in prediction of not just physico-chemical properties but also the biological activity of t...
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NIGELLA SATIVA SEED, A NOVEL BEAUTY CARE INGREDIENT: A REVIEW
Nigella sativa seed is one of the spices, which is referred by Prophet Mohammed as a herb of blessing, which can cure everything other than death. Therapeutic potential of Nigella sativa seed has been very well studied by many researchers, but its use in cosmetic science is not very well studied. Nigella sativa seed is intensively studied for its chemical composition. It is reported to contains Th...
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DOSE OPTIMIZATION OF CEFTRIAXONE-SULBACTAM COMBINATION IN PEDIATRIC USING IN-VITRO SYSTEMS AND STOCHASTIC SIMULATIONS APPROACHES
Increase in complexity and cost associated with pediatric safety and efficacy studies have reduced the interest of pharmaceutical companies to study bio-therapeutics in pediatric population. Dose recommendations are being made as per patient body weight or body surface area, with the assumption of linearity in body size dose adjustments. In the present study, newer approach i.e. flat fixed age-bas...
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COMBINATORIAL CHEMISTRY: A REVIEW
Combinatorial chemistry is a new methodology by which we can simultaneously synthesize a number of possible compounds that could produce simultaneously a very large number of compounds, called libraries.Combinatorial chemistry involves the rapid synthesis or the computer simulation of a large number of different but often structurally related molecules or materials. Combinatorial chemistry is espe...
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