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OPTIMIZATION OF VARIOUS PROCESS PARAMETERS FOR FORMULATION OF MODEL ANTI-HYPERLIPIDEMIC DRUG BY USING DRY GRANULATION METHOD
The Tablet manufacturing process is a complex process, influenced by several process variables The aim of this study was to optimize blending; roller compaction and tablets compression processes using design space approach for a model Anti- Hyperlipidemic drug Fluvastatin. During each processes there are several factors which may affect product quality. So the main objective of present work was ...
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SIMULTANEOUS ESTIMATION OF MEFENAMIC ACID AND DICYCLOMINE HYDROCHLORIDE BY SPECTROSCOPIC METHODS
A novel, simple, accurate, sensitive, reproducible, economical spectroscopic method was developed and validated for the determination of Mefenamic acid and Dicyclomine hydrochloride in combined dosage form. Three different analytical methods, Absorption correction method, Differential derivative method, Simultaneous equation method were developed for estimation of Dicyclomine hydrochloride(10mg)...
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AN OVERVIEW OF DANDRUFF AND NOVEL FORMULATIONS AS A TREATMENT STRATEGY
This review gives an insight of the scalp condition- dandruff which affects more than 50% of the human population. Malassezia furfur is reported as the main cause of dandruff. This article aims at investigating other causes of dandruff which include microbial and non - microbial factors. These factors have been explained in this article. It also highlights the various treatment options and newer f...
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NEW ADVANCEMENTS OF BIOPLASTICS IN MEDICAL APPLICATIONS
The bio-plastics that are produced either from fossil material or can be synthesized from biomass or renewable resources, such as Poly-lactic acid (PLA), Polyethylene glycol (PEG) and Poly - ε - caprolactone (PCL) are been reported as a material of choice for biomedical applications due to their good physical properties such as crystallinity, storage modulus, glass transition temperature and bior...
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AN OVERVIEW ON TECHNOLOGY TRANSFER OF PHARMACEUTICAL INDUSTRY
The purpose of this review article is to discuss in detail about technology transfer in the pharmaceutical industry. The article highlights the objective, reasons for undergoing technology transfer, factors which affect technology transfer, steps involved in technology transfer process. Clearly explains the technology transfer documentation part this is an attempt to understand the aspects related...
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A CASE REPORT ON ATROPINE INDUCED PSYCHOSIS
The administration of atropine to a large population for treatment of intoxication carries the risk of allergic or toxic reactions in a small number of patients. It has been reported rarely in the literatures .We describe a cases of atropine-induced psychotic disorder in a substance abused patient and different approaches of management. Dryness of the mouth, blurred vision, photophobia and tach...
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BRIEF REVIEW ON: FLASH CHROMATOGRAPHY
In previous days, Column chromatography was used in many laboratories for preparative purposes as well as for reaction control in organic synthesis. Column chromatography is an extremely time consuming stage in any lab and can quickly become the bottleneck for any process lab. This leads to the development of novel preparative liquid chromatography in which mobile phase flows down by positive air ...
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ANTITUMOR ACTIVITY OF MIMOSA RUBICAULIS LAM AGAINST EHRLICH ASCITES CARCINOMA IN SWISS ALBINO MICE
The antitumor activity of the methanol stem extract of Mimosa rubicaulis lam (MEMR) was evaluatedagainst Ehrlich Ascites Carcinoma (EAC) tumor model in Swiss albino mice. After 24h of intraperitonial inoculation of tumor (EAC) cells in mice, MEMRwas administered at the dose of 100, 200 and 400mg per kg body weight orally for 13 consecutive days. After 24 h of the last dose and followed by eighteen...
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AUTHENTICATION METHODS FOR DRUGS USED IN AYURVEDA, SIDDHA AND UNANI SYSTEMS OF MEDICINE: AN OVERVIEW
Traditional systems of medicine in India include Ayurveda,Yoga, Naturopathy, Unani and Siddha. Among them Ayurveda, Siddha and Unani systems (ASU) use plants, minerals and animal products as main drugs to cure various ailments. There has been a boom in the usage of ASU drugs and export is appreciably high in the last two decades. ASU drugs may vary in composition and properties, unlike conventiona...
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HERBAL TREATMENT FOR URINARY STONES
Herbs and herbal drugs have created interest among the people by its clinically proven effects like immunomodulation, adaptogenic and antimutagenic. Also, the overuse of synthetic drugs, which results in higher incidence of adverse drug reactions, has motivated humans to return to nature for safe remedies. The problem of urinary stones or calculi is a very ancient one and many remedies have been e...
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