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AN APPROACH TO BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION: A REVIEW
Bioanalytical method development is the process of creating a procedure to enable a compound of interest to be identified and quantified in a biological matrix. A compound can often be measured by several methods and the choice of analytical method involves many considerations. Analysis of drugs and their metabolites in a biological matrix is carried out using different extraction techniques like ...
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SAPINDUS MUKOROSSI (AREETHA): AN OVERVIEW
The objective of this review is to form a short compilation of phytochemical screening, pharmacological activity and some analytical methods available for Sapindus mukorossi plant. Although the plant is of importance in Ayurvedic system of medicine mainly as cleansing agent, a review article based on the phytochemical and pharmacological screening of Sapindus mukorossi is not so far reported. The ...
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EMULGEL-NOVEL TOPICAL DRUG DELIVERY SYSTEM–A COMPREHENSIVE REVIEW
Emulgel systems are currently of attention to the pharmaceutical scientists because of their substantial potential to act as drug delivery vehicle by incorporating a broad range of drug molecules. These are either emulsion of water in oil type or oil in water, which is gelled by mixing it with a gelling agent. Incorporation of emulsion into gel makes it a dual control release system & also inc...
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MEDICINAL PLANTS – FROM TRADITIONAL USE TO TOXICITY ASSESSMENT: A REVIEW
Herbal medicine is gaining popularity once again and there is an increased interest in green medicine simply because it is considered as safe. Traditionally also plants and plant extracts were used to cure many diseases and disorders. However, before usage it is of utmost important to ensure its safety. The extract may be therapeutically very efficient but if it’s toxicity assessment is not wo...
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SPECTROPHOTOMETRIC DETERMINATION OF PARACETAMOL DRUG USING 8-HYDROXYQUINOLINE
A rapid and simple spectrophotometric method is reported here for the determination of paracetamol in a commercially available tablet formulation. The method is based on the diazotization of hydrolyzed paracetamol with 8-hydroxyquinoline as a coupler to form stable azo dyes color solution. The concentration of drug paracetamol was investigated by spectrophotometrically. The azo dyes formed with 8-...
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DEVELOPMENT AND EVALUATION OF HERBAL FORMULATION FOR THE TREATMENT OF ACNE
Acne vulgaris is a most common skin disorder of pilosebaceous unit that affect areas containing the largest oil glands, including the face, back, and trunk. It is generally characterized by formation of seborrhea, comedone, inflammatory lesions. Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. Staphylococcus aur...
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COSTUS IGNEUS – A THERAPEUTIC ANTI-DIABETIC HERB WITH ACTIVE PHYTOCONSTITUTENTS
Objective: Diabetes mellitus is an interminable metabolic disorder that has highly affected human health and quality of life. Conventional agents are being applied to control this disorder along with lifestyle management. But they are not totally effective and nobody has ever been diagnosed with full recovery of diabetes. Medicinal plants have been used for greater extent for control of diabetes m...
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DESIGN, EVALUATION AND RECENT TRENDS IN TRANSDERMAL DRUG DELIVERY SYSTEM: A REVIEW
Transdermal drug delivery system (TDDS) is topically administered dosage form in the form of patches which deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. By this constant concentration of drug remain in blood for long time. Polymer matrix, drug, permeation enha...
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A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL RESEARCH – REMEDY FOR SICKLE CELL DISEASE
Aim: This article focuses on the current review of world-wide medicinal plants studied for their phytochemical investigations, various biological activities and clinical studies in relation to their use for treatment of Sickle cell disease. Method: All relevant literature databases were searched up to 18 September 2014. The search terms were plant, herb, herbal therapy, phytotherapy, sickle cell a...
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AN OVERVIEW ON NANOEMULSION: A NOVEL APPROACH
The nanoemulsion is one of the most efficient dispersed nanosystems of droplet size ranging to submicron size. Nanoemulsions/ Sub-micron emulsions (SMEs)/ Mini-emulsions are thermodynamically stable transparent or translucent dispersions of oil and water stabilized by an interfacial film of surfactant and co surfactant molecules having a droplet size of less than 100 nm. This review provides bri...
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