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SAPINDUS MUKOROSSI (AREETHA): AN OVERVIEW
The objective of this review is to form a short compilation of phytochemical screening, pharmacological activity and some analytical methods available for Sapindus mukorossi plant. Although the plant is of importance in Ayurvedic system of medicine mainly as cleansing agent, a review article based on the phytochemical and pharmacological screening of Sapindus mukorossi is not so far reported. The ...
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IMMOBILIZATION AND ESTIMATION OF ACTIVITY OF YEAST CELLS BY ENTRAPMENT TECHNIQUE USING DIFFERENT MATRICES
Background: It becomes clear that living processes were based on the action of enzymes. Cell immobilization serves as a useful tool for the immobilization of intracellular enzymes. The purpose of study is to improve economically important processes by attaching the yeast cells to matrices. Methods: In this analytical study by using mixed models of matrices like (sodium alginate alone, sodium algin...
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LIVER SPECIFIC DRUG TARGETING STRATEGIES: A REVIEW
Drug delivery to liver is one of the most challenging research areas in pharmaceutical sciences. The some physiological barrier such as opsonization, mechanical entrapment by pulmonary vascular bed, uptake by RES represents an insurmountable obstacle for a large number of proteins and drugs, including antibiotics, antineoplastic agents and antiviral agents to target liver disorders. Therefore, var...
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SPECTROPHOTOMETRIC DETERMINATION OF PARACETAMOL DRUG USING 8-HYDROXYQUINOLINE
A rapid and simple spectrophotometric method is reported here for the determination of paracetamol in a commercially available tablet formulation. The method is based on the diazotization of hydrolyzed paracetamol with 8-hydroxyquinoline as a coupler to form stable azo dyes color solution. The concentration of drug paracetamol was investigated by spectrophotometrically. The azo dyes formed with 8-...
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PHYTOCHEMISTRY AND PHARMACOLOGY OF OXALIS CORNICULATA LINN.: A REVIEW
Many herbal remedies have been employed in various medical systems for treatment and management of different diseases. The plant Oxalis corniculata Linn. has been used in different system of traditional medication for the treatment of diseases and ailments of human beings. β-sitosterol, betulin, 4-hydroxybenzoic acid, ethyl gallate, methoxyflavones, apigenin, and 7-O-β-D-glucopyranoside were pre...
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EMULGEL-NOVEL TOPICAL DRUG DELIVERY SYSTEM–A COMPREHENSIVE REVIEW
Emulgel systems are currently of attention to the pharmaceutical scientists because of their substantial potential to act as drug delivery vehicle by incorporating a broad range of drug molecules. These are either emulsion of water in oil type or oil in water, which is gelled by mixing it with a gelling agent. Incorporation of emulsion into gel makes it a dual control release system & also inc...
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GLIFLOZIN A NEW CLASS FOR TYPE-II DIABETES MELLITUS: AN OVERVIEW
Gliflozin drugs is the sodium-glucose co-transporter 2 inhibitor is the newly developed class of oral hypoglycaemic agents used for the treatment of the type-II diabetes mellitus. This class approved by food and drug administration in 2013 for the treatment of diabetes, with a unique mechanism of action. SLGT-2 proteins are macromolecule reabsorb the filtered glucose molecule from (PCT) in the kid...
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THIRD GENERATION MATERIALS FOR WOUND DRESSINGS
An ideal wound Dressing need to be redefined based on the nature of wound and wound classifications. Since generations, wound have been defined as self-healing process, but chronic wounds and other wound requires handling and care from different parameters like moist conditions, biocompatibility, microbial infection to mention a few. Traditional methods have been continuously worked upon to delive...
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SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUGS: A REVIEW
Many water insoluble drugs present in class 2 and it is characterized by low solubility and high permeability. Solubility of drug can be enhancing by increasing of dissolution rate. Many solubilization techniques are available for increasing of solubility as well as permeability like micronization, coacervation, complexation, solid dispersion, and cosolvent. Poorly soluble and dissolution profile ...
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POLIO: A REVIEW
Postpolio syndrome (PPS) may affect survivors of paralytic poliomyelitis and is characterised by a complex of neuromuscular symptoms leading to a decline in physical functioning. The effectiveness of pharmacological treatment and rehabilitation management in PPS is not yet established. To review systematically the effects of any treatment for PPS compared to placebo, usual care or no treatment. Po...
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