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WARFARIN RESISTANCE-MECHANISMS AND MANAGEMENT
Anticoagulants are a class of drugs commonly used to prevent the blood from forming dangerous clots that could result in a stroke.Warfarin is an oral anticoagulant. Warfarin differs from most other drugs in that the dosage required to achieve a desired therapeutic effect varies greatly among individuals. Resistance to warfarin has been described as the inability to prolong the prothrombin time or ...
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SAPINDUS MUKOROSSI (AREETHA): AN OVERVIEW
The objective of this review is to form a short compilation of phytochemical screening, pharmacological activity and some analytical methods available for Sapindus mukorossi plant. Although the plant is of importance in Ayurvedic system of medicine mainly as cleansing agent, a review article based on the phytochemical and pharmacological screening of Sapindus mukorossi is not so far reported. The ...
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DILLENIA INDICA (OUTENGA) AS ANTI-DIABETIC HERB FOUND IN ASSAM: A REVIEW
Dillenia Indica, commonly known as elephant apple and locally known as outenga, is the handsome evergreen tree grows in the moist forest of sub-Himalayan region to Assam. The fruit grows in abundance and due to lack of knowledge and technical knowledge; most of these fruits are wasted. In Assam, traditionally the unripe fruits are used to make curries because of its sour taste and ripe fruits are ...
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EMULGEL-NOVEL TOPICAL DRUG DELIVERY SYSTEM–A COMPREHENSIVE REVIEW
Emulgel systems are currently of attention to the pharmaceutical scientists because of their substantial potential to act as drug delivery vehicle by incorporating a broad range of drug molecules. These are either emulsion of water in oil type or oil in water, which is gelled by mixing it with a gelling agent. Incorporation of emulsion into gel makes it a dual control release system & also inc...
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MOLSARI (MIMUSOPS ELENGI LINN.): A BOON DRUG OF TRADITIONAL MEDICINE
Mimusops elengi L. is an Indian origin herb used in the Unani and other traditional systems of medicine since long time. It is commonly called by the names Spanish cherry, West Indian Medlar or Bullet wood tree. This plant is frequently cultivated throughout India especially in north India for its ornamental appearance and fragrant flowers. All parts of plant such as leaf, root, fruit, seed, bark,...
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FORMULATION AND EVALUATION OF MICROCAPSULES OF TRIHEXYPHENIDYLE HYDROCHLORIDE BY SOLVENT EVAPORATION METHOD.
Trihexyphenidyle is a lipophilic antiparkinsonian drug with short half life. Practically slightly soluble in water makes formulation and delivery difficult. By formulating the same in the microcapsule by using biodegradable polymer Eudrajit L 100 and S 100, the half life and solubility can be altered and hence drug release pattern. Trihexyphenidyle microcapsules were prepared by solvent evaporatio...
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BHUT JOLOKIA (CAPSICUM CHINENSE JAQC): A REVIEW
The northeast region of India, considered as ‘hot spot’ of biodiversity, having unique ecological environment with hot and high-humidity conditions, has given rise to the world’s hottest chilli, ‘Bhut jolokia or Bih jolokia’, which is at least two times hotter than Red Savina Habanero in terms of Scoville heat units (SHU). The Assamese word “bhut” refers to the typical large pod size...
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EFFECTIVENESS OF VARMAM THERAPY FOR THE MANAGEMENT OF OSTEOARTHRITIS
Siddha system of medicine is the ancient traditional medicine practiced all over Tamil Nadu. Siddha system is bestowed with various specialities of few which are Varmam, Pranayamam, Yoga and Kayakarpam. This system has a vast repository of internal and external medicines; Varmam is one among such therapies used to treat multiple ailments, especially related to musculoskeletal and neurological defi...
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EFFICACY AND SAFETY OF VILDAGLIPTIN AND TENELIGLIPTIN IN PATIENTS OF TYPE 2 DIABETS MELLITUS INADEQUATELY CONTROLLED ON STABLE DOSES OF METFORMIN
This was a 24-week, randomized, open label study. Treatment-naive patients diagnosed with Type 2 diabetes mellitus were randomized into two groups, Group-1 (Vildagliptin 50 mg, twice dailyplus Metformin 500 mg, twice daily) and Group-2 (Teneligliptin 20 mg, once dailyplus Metformin 500 mg, twice daily). The primary objective was to compare fasting plasma blood glucose levels (FBG), 2-h post prandi...
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SPECTROPHOTOMETRIC DETERMINATION OF PARACETAMOL DRUG USING 8-HYDROXYQUINOLINE
A rapid and simple spectrophotometric method is reported here for the determination of paracetamol in a commercially available tablet formulation. The method is based on the diazotization of hydrolyzed paracetamol with 8-hydroxyquinoline as a coupler to form stable azo dyes color solution. The concentration of drug paracetamol was investigated by spectrophotometrically. The azo dyes formed with 8-...
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