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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

A Web of Science - ESCI Indexed Journal
Projected Impact Factor (2019): 1.230 , CiteScore (2017): 0.27

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5.

REVISITING THE ROLE OF PHYCOCYANIN IN CURRENT CLINICAL PRACTICE

C-phycocyanin (C-PC) is a biliprotein found in edible blue-green algae. Its anti-cancer, anti-inflammatory, anti-proliferative and anti-oxidant activities has been evidenced by many in vitro and in vivo studies. Anti-inflammatory activity of C-PC demonstrated by free radical scavenging, inhibition of DNA damage, and decreased ROS. Here, the effects of C-PC on cytotoxicity and cell signaling throug...

A. Soni *, M. Dubey , M. Verma , R. Dhankhar , V. Kaushal, R. Atri and R. Sabharwal

Department of Radiotherapy, PGIMS, Rohtak, Haryana, India

DOI: 10.13040/IJPSR.0975-8232.6(11).4588-00

4588-00

6811

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11.

3D-QSAR AND CONTOUR MAP ANALYSIS OF TARIQUIDAR ANALOGUES AS MULTIDRUG RESISTANCE PROTEIN-1 (MRP1) INHIBITORS

One of the major obstacles to the successful chemotherapy towards several cancers is multidrug resistance of human cancer cells to anti-cancer drugs. An important contributor to multidrug resistance is the human multidrug resistance protein-1 transporter (MRP1), which is an efflux pump of the ABC (ATP binding cassette) superfamily. Thus, highly efficacious, third generation MRP1 inhibitors, like t...

P, Kakarla, M. Inupakutika, A. R. Devireddy, S. K. Gunda, T. M. Willmon, Ranjana KC , U. Shrestha, I. Ranaweera, A. J. Hernandez, S. Barr, And M. F. Varela٭

Department of Biology, Eastern New Mexico University, Station 33, Portales, NM, 88130,USA

DOI: 10.13040/IJPSR.0975-8232.7(2).554-72

554-72

6806

1130

78.

DEVELOPMENT AND VALIDATION OF UV-VISIBLE SPECTROMETRIC METHOD FOR ESTIMATION OF WATER SOLUBLE VITAMIN RIBOFLAVIN

The present study describes a simple, accurate, precise and cost effective UV-Visible spectrophotometric method for the estimation of Riboflavin raw material. The Riboflavin is water soluble vitamin, so the solvent used throughout the experiment was 0.1N NaOH, the absorption maxima of drug was found at 445 nm. Beer’s law was obeyed in the range of 5ppm-30ppm. the developed method was successfull...

Himanshi Shah*, Shraddha Patel, Bhavik Patel, Nitin Solanki, Nurudin P. Jivani, Digbijay B. Kumar

Department of Quality Assurance, C.U. Shah College of Pharmacy and Research, Gujarat Technological University, Wadhwan-363 065, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(9).3462-66

3462-3466

6803

1036

46.

ANTI-OXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF CUCUMIS SATIVAS (CUCUMBER) FLOWERS

Cucumis sativus (Cucumbers) have not received as much press as other vegetables in terms of health benefits, but this widely cultivated food provides us with a unique combination of nutrients. At the top of the phytonutrient list for cucumbers are its cucurbitacins, lignans, and flavonoids. These three types of phytonutrients found in cucumbers provide us with valuable antioxidant, anti-inflammato...

N. Muruganantham *, S. Solomon and M.M. Senthamilselvi

Department of Chemistry, Roever Engineering College, Perambalur, Tamil Nadu, India

DOI: 10.13040/IJPSR.0975-8232.7(4).1740-45

1740-45

6787

1099

56.

PRELIMINARY PHYTOCHEMICAL ANALYSIS AND THIN LAYER CHROMATOGRAPHY OF THE EXTRACTS OF EXCOECARIA AGALLOCHA L.

Purpose: The focus of the present paper was a preliminary phytochemical and TLC analysis of the various extracts (root, stem, and leaf) of the mangrove plant Excoecaria agallocha L. Methods: Phytochemical analysis was carried out using the standard phytochemical assays. TLC analysis of the petroleum ether and chloroform fraction of the leaves was carried out using the solvent system Toluene: Ethyl...

M. Deepa * and C. K. Padmaja

SBST, VIT University, Vellore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.5(10).4532-42

4535-4542

6787

1940

2.

SUICIDE RISKS AMONG ADOLESCENTS: A LOOK BEHIND THE BLACK CURTAIN

This review article investigates the prevalent existence of suicide along with its risk factors and contributing factors leading to the culmination of them all, in an attempt to look behind the black curtain. Suicide is the result of an unbalanced scale between the good and bad. Every year 300,000 teenagers attempt and succeed at suicide worldwide. A set of emotions and unpleasant thoughts develop...

Norah Al Rohaimi

College of Medicine, Alfaisal University, Riyadh Kingdom of Saudi Arabia

DOI: 10.13040/IJPSR.0975-8232.7(6).2266-73

2266-73

6783

1260

5.

A REVIEW ON ENDEMIC INDIAN RESURRECTING HERB SELAGINELLA BRYOPTERIS (L.) BAK. ‘SANJEEVANI’

Selaginella bryopteris (L.) Bak. usually known as “Sanjeevani’, is a lithophyte with remarkable resurrection capabilities and medicinal properties. It is traditionally used for curing wounds and irregular menstruation, uterine disorders and other internal injuries. It contains a variety of secondary metabolites such as alkaloids, phenol and terpenoids etc due to which it can act as antioxidant...

Shweta Singh* and Rita Singh

Post Doctoral Fellow of UGC, Guru Gobind Singh Indraprastha University, University School Of Environment Management, 16 C Dwarka, New Delhi-110078, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(1).50-56

50-56

6776

2214

1.

HISTAMINE SUBTYPE 3 RECEPTOR ANTAGONISTS: CURRENT STATUS WITH FUTURE PROSPECTS IN DRUG DISCOVERY AND DRUG DEVELOPMENT

The  histamine  H3 receptor is  an  G protein-coupled  receptor that regulates neurotransmission  in  the  central  nervous  system  and plays a major role in cognitive and homeostatic functions. The third histamine receptor was discovered in 1983 by a traditional pharmacological approach, consisting of assessing the inhibitory effect of histamine on its own release from depolarized rat...

Shreya Singh and Satyendra K. Rajput*

Amity Institute of Pharmacy, Amity University, NOIDA, Uttar Pradesh-201303, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).502-09

502-509

6771

1870

43.

PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTUKONAM VARIKA)

About 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. Ten constituents from 10 peaks were identified. Terpinyl acetate (5.80%) and phytol isomer (5.12%) are as the major constituents and the minor constituents like oxira...

P.A. Mary Helen*, M.R. Aswathy, K.G. Deepthi, R. Rathi Mol, J. Jaison Joseph and S. Jaya Sree

Department of Biotechnology, Malankara Catholic College, Mariagiri, Kaliakkavilai – 629153, Kanyakumari District, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(2).823-28

823-828

6771

1268

9.

BOSWELLIA SERRATA ROXB. A TRADITIONAL HERB WITH VERSATILE PHARMACOLOGICAL ACTIVITY: A REVIEW

Boswellia serrata Roxb. is known as kundur in Unani medicine, belongs to the family Burseraceae. The plant is widely distributed in India, it occurs in dry hilly forests of Rajasthan, Madhya Pradesh, Gujarat, Bihar, Assam, Orrisa, central peninsular regions of Andhra Pradesh etc. In ancient times Hindus, Babylonians, Persians, Romans, Chinese, Greeks and the people of old American civilization use...

Arshiya Sultana*, Khaleeq Ur Rahman , A.R. Padmaja and Shafeeq Ur Rahman

Lecturer, Department of Amraze Niswan wa Qabalat (Obstetrics and Gynecology), National Institute of Unani Medicine, PG Institute of Research, Bangalore, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(6).2106-17

2106-2117

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