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ISOLATION AND IDENTIFICATION OF THE FLAVONOID “QUERCETIN” FROM TRIDAX PROCUMBENS LINN.
Tridax procumbens (Linn.) is an important medicinal plant belonging to the family Asteraceae. It is known for a number of pharmacological activities like antidiabetic, anticancer, anti-inflammatory, wound healing, hepatoprotective and antioxidant activity.Flavonoid “Quercetin” was isolated from the flowers of this plant. Dried flowers were Soxhlet with petroleum ether, chloroform, and methanol...
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DEVELOPMENT AND VALIDATION OF UV-VISIBLE SPECTROMETRIC METHOD FOR ESTIMATION OF WATER SOLUBLE VITAMIN RIBOFLAVIN
The present study describes a simple, accurate, precise and cost effective UV-Visible spectrophotometric method for the estimation of Riboflavin raw material. The Riboflavin is water soluble vitamin, so the solvent used throughout the experiment was 0.1N NaOH, the absorption maxima of drug was found at 445 nm. Beer’s law was obeyed in the range of 5ppm-30ppm. the developed method was successfull...
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ROLE OF ADHESIVES IN TRANSDERMAL DRUG DELIVERY: A REVIEW
Transdermal drug delivery systems (TDDS) also commonly known as “patches” are dosage forms designed to deliver a therapeutically effective amount of drug across a patient’s skin. The therapeutic performance of a transdermal delivery system (TDS) can be affected by the quality of contact between the patch and the skin. The adhesion of the TDS to the skin is obtained by using pressure-sensitiv...
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CRITICAL ROLES PLAY OF MAGNESIUM STEARATE IN FORMULATION DEVELOPMENT OF A HIGHLY SOLUBLE DRUG METFORMIN HYDROCHLORIDE
This article is giving emphasis on the decisive role of particle size of highly hydrophobic lubricant i.e. Magnesium Stearate, its concentration and lubrication time to establish the desired quality attributes of formulation containing highly soluble model drug Metformin Hydrochloride. Magnesium Stearate from two sources with different Particle size distribution (PSD) range was selected. It was ob...
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CHARACTERISATION OF NARIKELA LAVANA
Background: Narikela lavana is a classical formulation which has been described in the samhitas such as Chakradatta, Vangsena, Bhavaprakash, and Rasa tarangini. The main indication of Narikela lavana is Parinaam shoola which can be broadly correlated with Peptic ulcer as per the modern parameters. As the name suggests, Narikela lavana contains only two ingredients- Narikela (coconut) and saindhava...
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AN UPDATED REVIEW OF PHARMACOLOGICAL STUDIES ON AZADIRACHTA INDICA (NEEM)
Neem has become valuable plant in the world which shows the solutions for hundreds to thousands problems. Neem has become important in the global context today because it offers answers to the major concerns facing mankind. Neem has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a centre of attraction of modern medicine. Azadirachta indica (neem) is a rapidly gro...
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THREE GENERATIONS: PIMARY, SECONDARY AND TERTIARY GENERATIONS OF TRANSDERMAL DRUG DELIVERY SYSTEMS: A REVIEW
From this article, we get the knowledge about the transdermal patch, transdermal drug delivery system and anatomy of the skin. Now-a-days transdermal drug delivery, system is widely used in much disease. So, this article gives the knowledge about pre transdermal system, post transdermal drug delivery system and future of transdermal drug delivery systems and examines the benefits and limitations o...
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STANDARDIZATION OF YAKRIT PLIHANTAK CHURNA: AN AYURVEDIC POLYHERBAL FORMULATION
Most of the traditional systems of medicine are effective but they lack of standardization. So there is need to develop standardization technique. Central Council for Research in Ayurveda has given preliminary guidelines for standardization the conventionally used formulations. Standardization of herbal formulations is essential in order to assess the quality of drugs, based on the concentration o...
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A COMPREHENSIVE REVIEW ON CANCER AND ANTICANCER HERBAL DRUGS
Cancer is a major public health burden in both developed and developing countries. It is an abnormal growth of cells in body that can lead to death and globally the numbers of cancer patients are increasing day by day. There are several medicines available in the market to treat the various types of cancer but no drug is found to be fully effective and safe. Herbal medicines have a vital role in t...
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OXAZOLINES: THEIR SYNTHESIS AND BIOLOGICAL ACTIVITY
Heterocylic chemistry have been known for many years but in recent years heteocyclics received great attention. In heterocyclic chemistry oxazoline is one of the most important moiety. Oxazoline moiety shows a wide range of application such as in agriculture industry, pharmaceutical, food industry, natural product, medicine, polymers and various other industries. Oxazoline moiety constitutes the c...
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