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PELTOPHORUM PTEROCARPUM: CHEMICAL AND PHARMACOLOGICAL ASPECTS
The present work offers a review addressing the detailed chemistry and pharmacology of Peltophorum pterocarpum (belonging to Fabaceae family) regarded as one of the most significant plant species in traditional system of medicine. The plant is used in different parts of the world for the treatment of several ailments like stomatitis, insomnia, skin troubles, constipation, ringworm, insomnia, dysen...
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SYNTHESIS AND BIOLOGICAL SIGNIFICANCE OF PYRAZOLONES: A REVIEW
Heterocyclic compounds are acquiring more importance in recent years because of their pharmacological activities. Pyrazolones have a particular value due to their broad spectrum of biological activity and their wide ranging utility as synthetic tools in the design of various bioactive molecules. Pyrazolone is a five membered lactum ring, containing two nitrogen and one ketonic group in its structu...
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CHEMISTRY OF HYALURONIC ACID AND ITS SIGNIFICANCE IN DRUG DELIVERY STRATEGIES: A REVIEW
Hyaluronic acid is an important naturally occurring polysaccharide present in extracellular matrices. The network-forming, viscoelastic and the charge characteristics of hyaluronic acid are important to many biochemical functions of living tissues. Its involvement in many diseases such as cancer, arthritis and osteoporosis, and the fact that it has specific protein receptors present on the cell su...
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HYDROTROPHY: NOVEL SOLUBILITY ENHANCEMENT TECHNIQUE: A REVIEW
Drug discovery and development plays a major role in the world and serves mankind. The major criteria to be considered and given importance in drug development is the solubility of a drug. Among all newly discovered chemical entities, about 40% of drugs fail to reach the market due to their poor aqueous solubility or lipophilicity. Poor solubility is not only a problem for formulation development ...
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CRITICAL ROLES PLAY OF MAGNESIUM STEARATE IN FORMULATION DEVELOPMENT OF A HIGHLY SOLUBLE DRUG METFORMIN HYDROCHLORIDE
This article is giving emphasis on the decisive role of particle size of highly hydrophobic lubricant i.e. Magnesium Stearate, its concentration and lubrication time to establish the desired quality attributes of formulation containing highly soluble model drug Metformin Hydrochloride. Magnesium Stearate from two sources with different Particle size distribution (PSD) range was selected. It was ob...
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FORMULATION AND EVALUATION OF ENTERIC COATED ASPIRIN TABLET BY USING BIOEPOXY RESIN AS COATING MATERIAL
An enteric coating is a polymer barrier applied to oral tablets; it prevents dissolution and disintegration of tablet in the gastric environment. Some drugs like aspirin that have an irritant effect on the GI Track after administration, can be prepared as enteric-coated tablet. Aspirin is used to reduce fever and to relieve pain from various conditions. By coating aspirin tablet with polymer it pr...
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ETHNOPHARMACOLOGICAL PROPERTIES OF CURCUMA LONGA: A REVIEW
Curcuma longa(Turmeric) is a member of the ginger family (Zingiberaceae) and is thought to be indigenous to the Indian subcontinent. It is grown and harvested commercially in India, China, and many regions of tropical Southeast Asia. Turmeric is an approved food additive and is commercially available at low cost. Indigenous systems of medicine, including the Ayurvedic systems, have widely used tur...
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THREE GENERATIONS: PIMARY, SECONDARY AND TERTIARY GENERATIONS OF TRANSDERMAL DRUG DELIVERY SYSTEMS: A REVIEW
From this article, we get the knowledge about the transdermal patch, transdermal drug delivery system and anatomy of the skin. Now-a-days transdermal drug delivery, system is widely used in much disease. So, this article gives the knowledge about pre transdermal system, post transdermal drug delivery system and future of transdermal drug delivery systems and examines the benefits and limitations o...
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ANALGESIC AND ANTI-INFLAMMATORY HERBS: A POTENTIAL SOURCE OF MODERN MEDICINE
In recent time, scientific investigations of medicinal plants using indigenous medical systems has attracted a lot of attention globally. Nature has bestowed our planet with an enormous wealth of medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention and cure of diseases and ailments. Inflammation is compl...
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COMPARISON OF EFFICACY OF FERROUS CALCIUM CITRATE vs FERROUS ASCORBATE ON Hb STATUS IN ANAEMIC PREGNANT WOMEN
Objectives: To compare the efficacy of ferrous calcium citrate with ferrous ascorbate on Hb levels in anaemic pregnant women. Method: In this observational study, patients receiving ferrous ascorbate with elemental iron 100 mg were allocated to group A and those receiving ferrous calcium citrate with elemental iron 50 mg allocated to group B. After recording the baseline data, their Hb levels, s...
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