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AN UPDATED REVIEW OF PHARMACOLOGICAL STUDIES ON AZADIRACHTA INDICA (NEEM)
Neem has become valuable plant in the world which shows the solutions for hundreds to thousands problems. Neem has become important in the global context today because it offers answers to the major concerns facing mankind. Neem has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a centre of attraction of modern medicine. Azadirachta indica (neem) is a rapidly gro...
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EFFECT OF PROPRIETARY CHROMIUM COMPLEX AND ITS INDIVIDUAL COMPONENTS VERSUS CHROMIUM PICOLINATE, CHROMIUM POLYNICOTINATE AND CHROMIUM DINICOCYSTEINATE ON ENDOTHELIAL FUNCTION, BIOMARKERS AND LIPID PROFILE IN TYPE 2 DIABETICS – A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY
Background: Hyperglycemia may induce endothelial dysfunction. Chromium Supplementation enhances endothelial relaxation and may improve endothelial dysfunction. Present study was planned to evaluate effect of proprietary chromium complex(PPC) and its individual components on endothelial dysfunction and lipid profile in type 2diabetics. Methodology: Study was done in two parts. In part I, PPC 400mcg...
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PHARMACOGNOSTIC STUDIES ON LEAF OF JATROPHA GOSSYPIFOLIA L.
Since, the free radicals induced oxidative stress is posing threat present researchers are focusing on natural sources that could serve as antioxidants to combat the oxidative damage mediated diseases such as diabetes, atherosclerosis and cancer. In this context, present study was carried out to investigate the botanical characters, chemical composition and in vitro antioxidant potential of Jatrop...
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COMPLICATIONS ASSOCIATED WITH ANGIOPLASTY
For certain people, heart disease treatment can be achieved without surgery. Angioplasty and stend placement are the common, non-surgical procedures that can be used to open the blocked heart arteries. This technique involves five different procedures including: Percutaneous coronary angioplasty, Peripheral angioplasty, Carotid angioplasty, Renal angioplasty and Venous angioplasty. Carotid angiopl...
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RESEALED ERYTHROCYTES AS A NOVEL CARRIER FOR DRUG DELIVERY: A REVIEW
Drug delivery systems including chemical, physical and biological agents that can enhance the bioavailability, improve pharmacokinetics and reduce toxicities of the drugs. Carrier erythrocytes are one of the most promising biological drug delivery systems investigated in recent decades. Resealed Erythrocytes are biocompatible, biodegradable, possess long circulation half-life and can be loaded wit...
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A REVIEW ON COLON TARGETED DRUG DELIVERY SYSTEM
The oral route is considered to be the most preferred route for administration of drugs for systemic effect, but the oral route is not suitable to the administration of drug for lower gastrointestinal (GI) diseases, this happened due to their release at upper GI tract (stomach, small intestine), which further minimizes the accessibility of drugs at the lower GI tract. To overcome this difficulty, ...
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AN OVERVIEW ON VARIOUS MODIFICATIONS OF CHITOSAN AND IT’S APPLICATIONS
Chitosan is a natural polysaccharide which is widely exploited for its various applications. It has received much attention as a functional biopolymer especially in pharmaceutics and medicine because of its better biodegradability, biocompatibility, versatility and availability. The unique biological applications of chitosan are attributed to these specific properties. The chemical and biological ...
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COUMARINS: AN OVERVIEW OF MEDICINAL CHEMISTRY. POTENTIAL FOR NEW DRUG MOLECULES
Fusion of a pyrone ring with a benzene nucleus gives rise to a class of heterocyclic compounds called Benzopyrones, of which two distinct types are recognized: (1) benzo-α-pyrone commomly called coumarins and (2) benzo-ϒ-pyrone called chromones or flavanoids, latter differing from former only in the position of the carbonyl group in heterocyclic system. Coumarins have attracted considerabl...
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SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF THIAMINE HYDROCHLORIDE IN PURE FORM, PHARMACEUTICAL AND BIOLOGICAL FLUIDS
Thiamine hydrochloride, also known as Vitamin B1, is a water-soluble vitamin which is important biologically and pharmaceutically. A new simple and sensitive spectrophotometric method has been developed for the determination of Thiamine Hydrochloride (Vitamin B1) in pure form and biological fluids. The method is based on the diazotization reaction of Thiamine Hydrochloride with Procaine HCl which ...
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PELTOPHORUM PTEROCARPUM: CHEMICAL AND PHARMACOLOGICAL ASPECTS
The present work offers a review addressing the detailed chemistry and pharmacology of Peltophorum pterocarpum (belonging to Fabaceae family) regarded as one of the most significant plant species in traditional system of medicine. The plant is used in different parts of the world for the treatment of several ailments like stomatitis, insomnia, skin troubles, constipation, ringworm, insomnia, dysen...
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