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PELTOPHORUM PTEROCARPUM: CHEMICAL AND PHARMACOLOGICAL ASPECTS
The present work offers a review addressing the detailed chemistry and pharmacology of Peltophorum pterocarpum (belonging to Fabaceae family) regarded as one of the most significant plant species in traditional system of medicine. The plant is used in different parts of the world for the treatment of several ailments like stomatitis, insomnia, skin troubles, constipation, ringworm, insomnia, dysen...
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COMPLICATIONS ASSOCIATED WITH ANGIOPLASTY
For certain people, heart disease treatment can be achieved without surgery. Angioplasty and stend placement are the common, non-surgical procedures that can be used to open the blocked heart arteries. This technique involves five different procedures including: Percutaneous coronary angioplasty, Peripheral angioplasty, Carotid angioplasty, Renal angioplasty and Venous angioplasty. Carotid angiopl...
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NOVEL TOPICAL QUICK PENETRATING SOLUTION OF HEPARIN IN MANAGEMENT OF SUPERFICIAL THROMBOPHLEBITIS: RESULTS OF RANDOMIZED ACTIVE CONTROLLED TRIAL
Aim: To compare safety and efficacy of topical quick penetrating solution (QPS) of heparin 1000 IU/ml versus heparin gel 200 IU/g in the management of post infusion superficial thrombophlebitis. Methods: Total 202 patients of early, medium and advance stage ofsuperficial thrombophlebitis were randomized to receive either treatment. Treatments were applied 3 times daily until healing or for a ...
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EVALUATION OF ANTIMICROBIAL AND ANTIFUNGAL PROPERTY OF DHOOPANA KARMA (FUMIGATION) – BY “DHUP”AN AYURVEDIC DHOOPANA PRODUCT
There are millions of micro-organisms around us, amongst 20-25% are non pathogenic. Pathogenic microbes present in the environment around us are responsible for various health related problems. Reducing microbial load to non-pathogenic levels may be the purpose of traditional fumigation techniques like Dhoopana, Homa, and Havana etc. This is also evident from Ayurvedic literature wherein fumigat...
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AN OVERVIEW ON ARACHIS HYPOGAEA PLANT
The peanut or groundnut (Arachis hypogaea) is a species in the legume family (Fabaceae). There are different varieties like Virgina group, Spanish group, Runner group, Valencia group, Tennessee red and Tennessee white. Peanut consists of 30 essential nutrients and phytonutrients. Peanuts are a good source of vitamins & metals. Peanut hulls consist of crude fiber, cellulose, water, crude protei...
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DALBERGIA SISSOO LINN. AN OVERVIEW MORPHOLOGY, PHYTOCHEMISTRY AND PHARMACOLOGY
The present review is, therefore, an effort to give a detailed survey of the literature on its pharamacognosy, phytochemistry, traditional uses and pharmacological studies of the plant Dalbergia sissoo. The genus consists of 300 species among which 25 species occur in India. The generic name Dalbergia honors the Swedish brothers Nils and Carl Dalberg, who lived in the 18th century. Dalbergia sis...
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METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF EMPAGLIFLOZIN IN API
An accurate, precise and rapid RP-HPLC method was developed and subsequently validated for the determination of Empagliflozin in API. Better separation of the drug was achieved on Intersil column(150x40mm, 5 μm) with the mobile phase consisted of mixture of 0.01 M acetate buffer, methanol in ratio of (30:70v/v ) at flow rate of 2ml/min, with detection at 260nm using PDA detector. The retention...
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SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE CELECOXIB FOR PARENTERAL FORMULATIONS
Celecoxib, a diaryl substituted pyrazole, is practically insoluble in water which precludes its use in parenteral and liquid dosage forms. This study explores the solubility enhancement of celecoxib using hydrotropy and cosolvency solubilization approaches. The equilibrium solubility studies were performed using hydrotropes piperazine, sodium citrate, and urea and cosolvents PEG 200, PEG 400, PEG ...
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A REVIEW ON ELECTROPHORESIS, CAPILLARY ELECTROPHORESIS AND HYPHENATIONS
Electrophoresis is an effective analytical tool for separation, as it does not affect the molecular structure, and it is also highly sensitive to small differences in molecular charge and size of the analytes. Capillary electro-phoresis is a separation technique where the ions are separated based on their electrophoretic mobility with an applied voltage. So far, the research field of capillary ele...
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RECENT DEVELOPMENTS ON NATURAL TRANSDERMAL PENETRATION ENHANCERS
The drug delivery by oral route is so far most convenient and accepted route of drug delivery but now a days considerable interest has been increased in delivery of drugs through skin to the systemic circulation and for local effect. However, the outer most layer of the human skin, stratum corneum; possess the formidable barrier to drug penetration thereby reducing bio-availability. Most of the dr...
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