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ANTIBACTERIAL ACTIVITIES AGAINST PYOGENIC PATHOGENS
Pyogenic infection refers to bacterial infection that leads to the production of pus. Antibiotics to treat these pyogenic bacterial infections are routinely prescribed, toxicity of which is serious threat and makes chemotherapy more difficult. Management of pyogenic infections consists of aspiration or surgical drainage followed by appropriate antibiotics. A total of 50 samples were examined, 36...
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SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW
Solubility of orally administered drug is major challenge of pharmaceutical industry as nearly 35-40% of newly launched drugs possess low aqueous solubility which leads to their poor dissolution and low bioavailability, resulting in high intra & inter subject variability & lack of dose proportionality. This can be increased by different methods like salt formation, solid dispersion and com...
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NOSOCOMIAL INFECTION: SOURCE AND PREVENTION
Nowadays, Hospital-acquired infection is one of the significant issues, as the mortality rate is frequently increasing. This may be due to the unhygienic environment of various medical clinics and hospitals, a wide range of antibiotic uses. Nosocomial infections are those which are acquired by the patient within 48-72 h or 3 days of admission in the hospital or medical care unit. The microbes caus...
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A COMPREHENSIVE REVIEW OF PLANTS USED AS CONTRACEPTIVES
Evaluation of herbs for anti-fertility effects has been in progress worldwide for several decades to identify effective and safe substances for control of population explosion. This population explosion will have negative impact on our economic policies and would simultaneously misbalance our socio-economic infrastructure. Family planning has been promoted through several methods of contraception,...
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AN ANALYTICAL REVIEW OF PLANTS FOR ANTI DIABETIC ACTIVITY WITH THEIR PHYTOCONSTITUENT & MECHANISM OF ACTION
Diabetes and its different types is an age old disease for clinicians since centuries. Many aspects of Diabetes needs to be explored with respect to physiological actions of insulin and the various clinical features of this disease such as tissue complication , since this is life style disease , so proper treatment in relation to diet and anti diabetic agents is emphasized In fact, herbal treatmen...
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HERBAL REMEDIES FOR TREATMENT OF HYPERTENSION
Hypertension is a common problem facing many peoples today. Although billions of dollars are spent annually for the treatment and detection of cardiovascular disease, current conventional treatments have done little to reduce the number of patients with hypertension. Alternative medicine offers an effective way to decrease the rising number of people with high blood pressure. Research has found a ...
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HERBAL MEDICINES USED DURING PREGNANCY, CHILDBIRTH AND POSTPARTUM CARE
Pregnancy and childbirth have been an essential part of human existence for millennia, but unfortunately the experience has not been easy for all women. Although many pharmaceutical drugs are available but the potential of drugs to cause harm, exemplified by thalidomide in 1958 cannot be ignored. Therefore, many pharmaceutical drugs are not recommended for use during pregnancy either because of kn...
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HERBAL AND ALLOPATHIC MEDICINE FOR KIDNEY, GALLBLADDER AND URINARY STONES: A REVIEW
Medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention of various ailments. Today large number of population suffers from kidney stone, gall stone and urinary calculi. Stone disease has gained increasing significance due to changes in living conditions i.e. industrialization and malnutrition. Changes in pr...
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ISOLATION, SCREENING AND CHARACTERIZATION OF L-ARGINASE PRODUCING SOIL BACTERIA
L-arginase (EC 3.5.3.1) is a therapeutic enzyme which catalyzes the hydrolysis of L-arginine to L-ornithine and urea. L-arginase is of keen interest due to its significance as an anti-cancer mediator against auxotrophic cancers. This enzyme is widely distributed and expressed in organisms like fungi, plants, non-chordates, and chordates, however very scarce report is available for L-arginase from ...
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DOSE OPTIMIZATION OF CEFTRIAXONE-SULBACTAM COMBINATION IN PEDIATRIC USING IN-VITRO SYSTEMS AND STOCHASTIC SIMULATIONS APPROACHES
Increase in complexity and cost associated with pediatric safety and efficacy studies have reduced the interest of pharmaceutical companies to study bio-therapeutics in pediatric population. Dose recommendations are being made as per patient body weight or body surface area, with the assumption of linearity in body size dose adjustments. In the present study, newer approach i.e. flat fixed age-bas...
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