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ANNONA SQUAMOSA LINN. (CUSTARD APPLE): AN AROMATIC MEDICINAL PLANT FRUIT WITH IMMENSE NUTRACEUTICAL AND THERAPEUTIC POTENTIALS
Alterative medication and natural remedies have been used from ancient time for the treatment and wellbeing of human. Medicinal plants are considered to be effective and for most important for the human health. Some of the natural medicinal plants are so common that we use them in daily life without knowing their medicinal importance. Annona squamosa belonging to the family Annonaceae is the best ...
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FORMULATION AND EVALUATION OF NATURAL PALM OIL BASED VANISHING CREAM
In present work, a new vanishing cream using a natural base from palm oil and palm kernel oil and standard vanishing cream using stearic acid were prepared. The creams were o/w emulsions containing suitable combination of oil phase and aqueous phase along with preservatives. Both creams were white, non-greasy and smooth on application. They were subjected to various parameters such as; pH, viscosi...
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BIOACTIVITY OF SECONDARY METABOLITES OF VARIOUS PLANTS: A REVIEW
Plants are an important source for the discovery of new products of medicinal value for drug development and plants secondary metabolites are unique sources for pharmaceuticals food additives, flavors, and other industrial values. The commercial importance of these secondary metabolites has resulted in a great interest in its production and in exploring possibilities of enhancing its production us...
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IMPORTANCE OF EMBELIA RIBES: AN UPDATE
Embelia ribes Burm F. is large scandent shrub, disturbed throughout India and belongs to the family Myrsinacae. It is commonly known as false black pepper or Vidanga. E. ribes grows in semi-evergreen and deciduous forests at an altitude of 1,500m found in central and lower Himalayas, Arunachal Pradesh, Assam, Bengal, Orissa, Andhra Pradesh and Madhya Pradesh throughout India. Embelia ribes h...
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SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW
Solubility of orally administered drug is major challenge of pharmaceutical industry as nearly 35-40% of newly launched drugs possess low aqueous solubility which leads to their poor dissolution and low bioavailability, resulting in high intra & inter subject variability & lack of dose proportionality. This can be increased by different methods like salt formation, solid dispersion and com...
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ASEPTIC PROCESSING RISK MANAGEMENT: A REVIEW
Aseptic processing is a widely used technology in the field of pharmaceutical, biotech, and medical device industries for the preparation of sterile materials. The term aseptic processing as it is applied in the pharmaceutical industry refers to the assembly of sterilized components and product in a specialized clean environment. Aseptic processes are some of the most difficult processes to conduc...
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IN-SITU BUFFERED FORMULATION: AN EFFECTIVE APPROACH FOR ACID LABILE DRUG
“Acid labile drug” means a drug that is easily destroyed in acidic environment, Stomach is the main site for drug absorption mainly by oral rout. The pH of the stomach is acidic so the absorption of acid labile drugs through stomach is difficult. For this resign the drugs should be formulated as enteric coated or may be administered through parenteral rout. These approaches are effective but t...
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TRADITIONAL INDIAN MEDICINAL PLANTS WITH POTENTIAL WOUND HEALING ACTIVITY: A REVIEW
In last few decades, there has been a great progress in understanding the biochemical and cellular events of normal wound healing. Healing of wounds, either accidental or surgical interventions, involves complex activities of blood cells, tissues, soluble mediators, cytokines and several growth factors. This increased cellular activity of damaged tissue enhances metabolic demands and active drug t...
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CO-CRYSTALLIZATION- A TECHNIQUE FOR SOLUBILITY ENHANCEMENT
Co-crystals consists of API and a stoichiometric amount of a pharmaceutically acceptable co-crystal former. Pharmaceutical Co-crystals are nonionic supramolecular complexes and can be used to address physical property issues such as solubility, stability, and bioavailability in pharmaceutical development without changing the chemical composition of the API. Cocrystal is a crystalline entity formed...
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HERB-DRUG INTERACTION: AN OVERVIEW
Plants have always provided an important source of medicines. They may be used by natives in folk medicine and later adopted by conventional western medicine as their efficacy was confirmed. Any pharmacological modification caused by herbal substances to another prescription medication (diagnostic, therapeutic or other action of a drug) in or on the body. An herb might increases or decreases the e...
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