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ASTAXANTHIN: A POTENTIAL CAROTENOID
Astaxanthin, a member of the carotenoid family, is a dark-red pigment which is the main carotenoid found in the marine world of algae and aquatic animals. Astaxanthin, is present in many types of seafood, including salmon, trout, red sea bream, shrimp and lobster, as well as in birds such as flamingo and quail. Synthetic Astaxanthin dominates the world market but recent interest in natural sources...
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MOUTH DISSOLVING TABLETS: AN OVERVIEW
The gold standard in pharmaceutical industry is the oral delivery because it is the easiest, safest, economical and convenient method for the drug delivery. Mouth dissolving tablets have becomes the most demanding application during last decades and in the pharmaceutical industry this field has become a rapidly area. Mouth dissolving tablets during insertion in the mouth should have to dissolve or...
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A DETAILED REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM
Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora. Oral mucosal drug delivery system provides local and systemic action. In this review, attention is focused to give regarding physiology of oral mucosal including tissue pe...
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SOLID DISPERSIONS: A REVIEW ON DRUG DELIVERY SYSTEM AND SOLUBILITY ENHANCEMENT
Solid dispersions, defined as the dispersion of one or more active pharmaceutical ingredient in a carrier at solid state and an efficient technique to improve dissolution of poorly water-soluble drugs to enhance their bioavailability. Poor water solubility is one of the major problems for the various types of drugs and various approaches have been introduced for the enhancement of solubility of su...
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KALANCHOE PINNATA: PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE
The main objective of this review is to provide advance information for the drug discovery research from the divine herb Kalanchoe pinnata, which contains a wide range of active compounds, including alkaloids, triterpenes, glycosides, flavonoids, steroids, bufadienolides, lipids and organic acids. The pharmacological studies are reviewed and discussed, focussing on activities as immunomodulator, C...
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MEDICINAL PLANT LEAVES USED BY LOCAL PRACTITIONERS OF COIMBATORE DISTRICT, TAMIL NADU, INDIA
This present investigation was an attempt to an ethno botanical survey which was carried out by the local practitioners of Coimbatore district in Tamil Nadu. During the survey 48 medicinal plant leaves are identified which were used as medicine for several diseases either in single or in combination with some other ingredients. In the first phase the Botanical Name, Family, Local Name and uses of ...
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ANTIBACTERIAL ACTIVITIES AGAINST PYOGENIC PATHOGENS
Pyogenic infection refers to bacterial infection that leads to the production of pus. Antibiotics to treat these pyogenic bacterial infections are routinely prescribed, toxicity of which is serious threat and makes chemotherapy more difficult. Management of pyogenic infections consists of aspiration or surgical drainage followed by appropriate antibiotics. A total of 50 samples were examined, 36...
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AN OVERVIEW ON BUCCAL DRUG DELIVERY SYSTEM
Buccal drug delivery has gained significant attention and momentum since it offers remarkable advantages. Over past few decades, buccal route for systemic drug delivery using mucoadhesive polymers to significantly improve the performance of many drugs has been of profound interest. This review article is an overview of buccal drug delivery systems encompassing a review of oral mucosa, formulation ...
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BIOLOGICAL ACTIVITIES OF FLAVONOIDS: AN OVERVIEW
Background: Plants and herbs consumed by humans are the rich sources of phytonutrients compounds synthesized in plants itself. Such bioactive substances are responsible for the plant’s antioxidant and medicinal values. Flavonoids are an essential group of naturally occurring polyphenolic compounds, and its flavan nucleus characterizes it. It is one of the most common classes of compounds availab...
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DESIGN AND EVALUATION OF TOPICAL HYDROGEL FORMULATION OF DICLOFENAC SODIUM FOR IMPROVED THERAPY
Topical gel preparations are intended for skin application or to certain mucosal surfaces for local action or transdermal penetration of medicament or for their emollient or protective action. Topical delivery of drugs can be achieved by incorporating drug into the gel matrix for effective delivery of drugs, thus avoiding first pass metabolism and for increased local action in pain management and ...
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