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MEDICINAL USE OF AN ANCIENT HERB MOMORDICA CYMBALARIA: A REVIEW
Momordica cymbalaria (Hook, Fenzl) is a vine of Momordica genus found in the Indian states of Karnataka, Madhya Pradesh, Maharashtra, Andhra Pradesh and Tamil Nadu. The medicinal herb also been named Luffa tuberose (Roxb) or Momordica tuberose (Roxb). Momordica cymbalaria is commonly known as Karchikai (Kannada) or Athalakkai (Tamil) or Kasarakayee (Andhra Pradesh) and Kakrol (India). Momordica cy...
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AN OVERVIEW OF DANDRUFF AND NOVEL FORMULATIONS AS A TREATMENT STRATEGY
This review gives an insight of the scalp condition- dandruff which affects more than 50% of the human population. Malassezia furfur is reported as the main cause of dandruff. This article aims at investigating other causes of dandruff which include microbial and non - microbial factors. These factors have been explained in this article. It also highlights the various treatment options and newer f...
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MIMOSA PUDICA LINN- A SHYNESS PRINCESS: A REVIEW OF ITS PLANT MOVEMENT, ACTIVE CONSTITUENTS, USES AND PHARMACOLOGICAL ACTIVITY
To cure all aliments of mankind, nature provides a complete store house of remedies for time honored period.In legume family, Mimosa is one of the largest genera which distribute more than 500 species. This article aims to provide a comprehensive review on plant movement, chemical constituents, pharmacological activities and uses on Mimosa pudica, sensitive plant. Its habitat are lowland tropi...
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A CASE REPORT ON ATROPINE INDUCED PSYCHOSIS
The administration of atropine to a large population for treatment of intoxication carries the risk of allergic or toxic reactions in a small number of patients. It has been reported rarely in the literatures .We describe a cases of atropine-induced psychotic disorder in a substance abused patient and different approaches of management. Dryness of the mouth, blurred vision, photophobia and tach...
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NEW ADVANCEMENTS OF BIOPLASTICS IN MEDICAL APPLICATIONS
The bio-plastics that are produced either from fossil material or can be synthesized from biomass or renewable resources, such as Poly-lactic acid (PLA), Polyethylene glycol (PEG) and Poly - ε - caprolactone (PCL) are been reported as a material of choice for biomedical applications due to their good physical properties such as crystallinity, storage modulus, glass transition temperature and bior...
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C-PHYCOCYANIN OF SPIRULINA PLANTESIS INHIBITS NSP12 REQUIRED FOR REPLICATION OF SARS-COV-2: A NOVEL FINDING IN-SILICO
SARS-CoV-2 or COVID-19 is one of the deadly pandemics faced by the world population, which has infected 7 million and claimed the lives of 0.4 million people. In spite of a few drugs available to control the pandemics, a formal vaccine is the least that the world expects under the current scenario. However, the release of a vaccine is expected to come at the cost of its own time. SARS-CoV-2 replic...
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PHYTOSOMES: A NOVEL DRUG DELIVERY FOR HERBAL EXTRACTS
Novel drug delivery system is a novel approach to drug delivery that addresses the limitations of the traditional drug delivery systems. Our country has a vast knowledge base of Ayurveda whose potential is only being realized in the recent years.The effectiveness of any herbal medication is dependent on the delivery of effective level of the therapeutically active compound. Severe limitation exist...
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TWENTY EIGHT DAYS ORAL ADMINISTRATION ASSESSMENT OF HYDNORA AFRICANA THUNB. AQUEOUS ROOT EXTRACT ON KEY METABOLIC MARKERS OF WISTAR RATS
Hydnora africana Thumb (Hydronaceae) is a parasitic flowering plant with significant global ethnomedicinal value. This study evaluated the toxicological effects of the acute and sub-acute dosing treatments of the aqueous root extract of Ha in male and female wistar rats using OECD guidelines 423 and 407. For the acute study, the extract was administered to the animals at single oral graded doses o...
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STRESS DEGRADATION BEHAVIOR OF PREGABALIN, IDENTIFICATION OF DEGRADATION IMPURITIES AND DEVELOPMENT OF STABILITY INDICATING UPLC METHOD
A novel, high-throughput, reverse phase-ultra performance liquid chromatographic (RP-UPLC) method has been developed for the quantification of Pregabalin and its related impurities in drug substance. The stability-indicating capability of the developed method is demonstrated using forced degradation samples from stress conditions such as hydrolysis, oxidation, thermal and photolytic degradation. T...
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GELATIN NANOPARTICLE: PREPARATION, CHARACTERIZATION AND APPLICATION IN DRUG DELIVERY
Nanotechnology plays an important role in advanced biology and medicine research particularly in the development of potential site-specific delivery systems with lower drug toxicity and greater efficiency. In terms of nanopharmaceutics, gelatin was already considered as interesting biodegradable base material in the early days of particle development. The interest was based on the facts that gelat...
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