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ISOLATION AND CHARACTERIZATION OF BIOACTIVE ACTINOMYCETES FROM SOIL IN AND AROUND NAGPUR
ABSTRACT: Fifteen soil samples were collected from different locations near Nagpur i.e. from Nagpur, Bhandara and Chandrapur. Air drying and pre-treatment of soil samples with CaCo3 (1%) were found to be most effective for isolation of actinomycetes. Five different selective media were used for the isolation of actinomycetes and the best growth was observed in yeast malt extract agar medium with 1...
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PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF BACOPA MONNIERI – AN ETHNOMEDICINAL PLANT
In recent times, the use of herbal products has increased tremendously in the developing as well as in developed countries. Bacopa monnieri is one of the most important medicinal plant that has been consumed for thousands of year as a memory enhancing, anti-inflammatory, analgesic, antipyretic, sedative and anti-epileptic agent. For many years, a lot of commercial and medicinal researches have bee...
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A COMPARATIVE STUDY TO EVALUATE ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY OF COMMONLY USED PROTEOLYTIC ENZYMES AND THEIR COMBINATION WITH DICLOFENAC IN RATS
Introduction: Proteolytic enzymes like serratiopeptidase, trypsin and chymotrypsin are used for prolonged period for edema resolution in post-operative patients, arthritis, tooth extraction etc. either alone or with other anti-inflammatory agent. Various trials have supported and refused the role of enzymes as anti-inflammatory agents. No study was found for analgesic property of proteolytic enzym...
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POLYPHENOLIC COMPOSITION AND ANTIMICROBIAL POTENTIAL OF METHANOLIC CORIANDER (CORIANDRUM SATIVUM) SEED EXTRACT
The coriander seedextract in 80% methanol is examined for the polyphenol composition and the antimicrobial potential against pathogenic bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus pumilus. Gallic acid, caffeic acid, ellagic acid, quercetin and kaempferol are principle polyphenolics identified and quantified in the coriander extract by HPLC. The antimicrob...
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THERAPEUTIC POTENTIAL OF WITHANIA SOMNIFERA: A REPORT ON PHYTO-PHARMACOLOGICAL PROPERTIES
Withania somnifera belongs to the Solanaceaefamily, commonly known as Ashwagandha, Indian ginseng or Winter cherry. It is an important commercial medicinal crop, considered as similar to Panax ginseng in Chinese medicine. Different parts of this plant are used in traditional medicine for the treatment of various ailments. It provides defense against diseases, adverse environmental factors and help...
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NATURAL COLORANTS FROM PLANTS FOR WELLNESS INDUSTRY
Colorants are widely used in food, cosmetics, pharmaceutical, nutraceutical and textile industry to improve customer perception and acceptability. The hazardous effects and legislation of synthetic dyes minimize its applications thus the search for natural pigments is in trend. Plant natural pigments are widely used as alternative not only because of their high availability as colouring agent, but...
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EFFECT OF SEASONAL VARIATION ON SECONDARY METABOLITES OF MEDICINAL PLANTS
Seasonal fluctuations are periodical series, and have impact on availability of active principles in medicinal plants hence, therapeutic efficacy also get influenced. The survey of several scientific studies published in scientific journals of international repute indicates this fact. The studies reported that essential oil component shows a rhythmic increase in oil production throughout the growi...
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FEMALE INFERTILITY: AN OVERVIEW
Female infertility is the major disorder which has altered the man kind foe lack of conception and reproducibility, stressful world, excess radiation, lack of biological food, genetically disorder ,changing life style, increased electronic discharge have resulted the female infertility. Infertility/ childlessness cause great personal suffering & distress. Most of this agony & misery is hid...
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GOLD NANO-CONJUGATES: A LEAP IN CANCER TREATMENT
The use of nanoparticles as drug delivery and targeting agents has led to immense progress in the field of biomedicine and diagnostics. Likewise gold nanoparticles can be conjugated with various molecules, for instance, to plasmid DNA for gene therapy, to various drugs for antibacterial and anticancer properties, to several antibiotics and peptides for immunological and diagnostic purposes. The re...
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DEVELOPMENT AND VALIDATION OF UV-VISIBLE SPECTROMETRIC METHOD FOR ESTIMATION OF WATER SOLUBLE VITAMIN RIBOFLAVIN
The present study describes a simple, accurate, precise and cost effective UV-Visible spectrophotometric method for the estimation of Riboflavin raw material. The Riboflavin is water soluble vitamin, so the solvent used throughout the experiment was 0.1N NaOH, the absorption maxima of drug was found at 445 nm. Beer’s law was obeyed in the range of 5ppm-30ppm. the developed method was successfull...
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