Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
DRUG UTILIZATION TRENDS OF ORAL ANTI-DIABETIC AGENTS AMONG DIABETES MELLITUS TYPE 2 PATIENTS IN A TERTIARY CARE HOSPITAL
Diabetes is a group of metabolic diseases and emerged as a major healthcare problem. According to the International Diabetes Federation (IDF), India has a large number of people suffering from diabetes, which will increase to almost 101 million by the year 2030. The pharmacotherapies of diabetes mellitus are diversified in their mechanism of action, safety profiles and tolerability. Drug utilizati...
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A NEW ASSAY METHOD DEVELOPMENT AND VALIDATION OF TWO ANTI-CANCER DRUGS BY USING EFFECTIVE LIQUID CHROMATOGRAPHIC METHOD
A simple, sensitive and rapid chromatographic method was developed and validated for quantification of Mitomycin and Fluorouracil in bulk and pharmaceutical dosage form using Symmetry C18 (4.6 × 150 mm, 3.5 µ) column. The mobile phase consists of buffer, 0.1% Ortho Phosphoric acid (OPA), and acetonitrile in the ratio of 50:50 v/v. The flow rate is maintained as at 1.0 ml/min; detection was carri...
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UTILIZATION OF GLUTEN-FREE COMPOSITE FLOUR NUTRITIONAL, PHYTO-CHEMICAL AND FUNCTIONAL PROPERTIES EVALUATION
Celiac disease an antibody-mediated enteropathy which is a lifelong condition where there is intolerance towards gluten. The only treatment till now is the gluten-free diet. The aim of this study was to investigate proximate, phytochemical and functional property analysis of gluten-free composite flour. The proximate analysis of composite flour for the most acceptable sample showed moisture (10.97...
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DEVELOPMENT AND IN-VITRO EVALUATION OF CENTELLA ASIATICA AND SILVER SOLUTION COATED SUTURES FOR ANTIBACTERIAL ACTIVITY
The research aim is to develop and evaluate Centella asiatica Chloroform extract and silver-coated suture against the most common organisms that cause surgical site infections (SSI) by in-vitro methods. This prospective study is to coat the Centella asiatica (CA) extract to the suture along with the silver nitrate solution. In this study, a suture filament was formulated with Poly Lactic Glycolic ...
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ISOLATION AND CHARACTERISATION OF L-GLUTAMINASE PRODUCING FUNGI FROM MARINE SOURCE
L-glutaminase [EC.3.5.1.2] is an amidohydrolase that catalyzes the hydrolytic deamination of L-glutamine, resulting in the production of L-glutamic acid and ammonia. The L-glutaminase has received a significant attention due to its potential as an anticancer agent. In the present study, soil sediments were collected from the estuaries region of Parangipettai, Cuddallore District, Tamil Nadu. The i...
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A NEW DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR THE DETERMINATION OF ANTI-RETROVIRAL DRUGS IN PHARMA-CEUTICAL DOSAGE FORM
In this study, a new simple, rapid and accurate, sensitive isocratic method was developed for the simultaneous determination of the Anti-retroviral drugs in pharmaceutical dosage forms. The chromatography was run through Denali C18 column (150 x 4.6 mm and 5 µm particle size). Mobile phase containing mixer of buffer 0.1% OPA (PH.4.6) acetonitrile is taken in the ratio 40:60 was pumped through col...
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TRANSDERMAL DRUG DELIVERY SYSTEM: AN ATTRACTIVE APPROACH FOR TREATMENT OF NEUROLOGICAL DISORDERS
Neurodegenerative diseases are progressive degeneration of certain nerve cells causing ataxias and dementia affecting millions of people worldwide. Transdermal drug delivery systems – “patches” represent an attractive alternative to the conventional method and have made an important contribution to the management of the various medical conditions. A transdermal patch is a medicated adhesive ...
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NANO STRUCTURED LIPID CARRIER SYSTEM- A NOVEL TARGETING CARRIER
Oral administration of drugs is considered a convenient route; however, various drugs that are insoluble in water or cannot permeate across gastrointestinal tract membrane cannot be delivered by this route. To enhance the permeability through the physiological barriers, lipophilic drugs are introduced but, lipophilic drugs have low oral bioavailability. To enhance the bioavailability, a third-gene...
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NATURAL GELLING AGENTS POLYMER IN PHARMACEUTICAL PREPARATION
Pharmaceutical preparation mostly contains active ingredients and excipients. The function of excipients to improve the physicochemical properties of pharmaceutical manufacturing products. In pharmaceutical preparation, polymer plays a key role act as excipients in any dosage formulation development. Polymers are derived from the source of natural and synthetic. The polymer should have basic prope...
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MANNICHBASES: AN OVERVIEW OF HETEROCYCLIC COMPOUND WITH VARIOUS BIOLOGICAL ACTIVITIES
In Organic chemistry, largest families of organic compounds belong to heterocyclic compounds. In place of a carbon atom incorporation of an oxygen, a nitrogen, a sulfur, or an atom of a related element gives rise to a heterocyclic compound..Heterocyclic compounds are of very essential for our day-to-day life. It has a broad range of applications in medicinal chemistry as well as in agrochemicals p...
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