Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
EFFECTS OF STREPTOZOTOCIN- INDUCED TYPE I DIABETES MELLITUS ON CATION CONTENTS IN URINARY BLADDER TISSUES OF THE RAT
Diabetes mellitus is known to induce microvascular changes and alterations to neuronal functions. Diabetic neuropathy and diabetic nephropathy are two of the major long-term complications of diabetic mellitus (DM). The main aim of the comparative study is to investigate the role of cations contents compared to the age matched control.Adult rats were humanely killed and detrusor muscles of urinary ...
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TO INVESTIGATE THE EFFECTS OF GINGER-JUICE (ZINGIBER OFFICINALE ROSCOE) ON AMPHETAMINE-INDUCED LOCOMOTOR ACTIVITY IN RAT
To investigate the effects of ginger-juice (Zingiber officinale roscoe) on amphetamine-induced locomotor activity in rat. Methods: (A) Albino rats (n=6-12) were administered G.J at the single doses (4 ml/rat, p.o) as single administration (acute) and chronic treatment over period of 7 days. Following this assessment was done. Effect of treatment with G.J acutely and chronically (7days) administere...
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THE CLINICOPATHOLOGICAL PROFILE IN PATIENTS WITH EPITHELIAL OVARIAN CARCINOMA
The malignant tumors of ovary are a group of disease with varying clinical and biological behavior. It is fifth leading cause of death from cancer in women and the leading cause of death from gynecological cancer. This retrospective study has been undertaken to analyze patients of epithelial ovarian cancers. These cases were analyzed for various features like age, stage at presentation, histologic...
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COMPARATIVE ANALYSIS OF DRUG-INDUCED PARKINSONISM LIKE BEHAVIORS IN C57BL6 BLACK MICE USING A FORCE PLATE ACTIMETER.
This study aims to compare the Parkinsonism behavior induced by two drugs: Tacrine (9-amino-1,2,3,4-tetrahydroaminoacridine hydrochloride hydrate and MPTP (1-methyl, 4-phenyl 1,2,3,6 tetrahydropyrolidine) using a Force Plate Actimeter (FPA). 25 C57BL/6 black mice were equally divided into two groups for 5mg/kg tacrine and 30mg/kg MPTP experiment. Both groups contained sham, 5mg/kg tacrine or 30mg/...
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UNDERSTANDING THE EVIDENCES AVAILABLE FOR USE OF TRANSDERMAL PATCHES IN THE TREATMENT OF ASTHMA – A REVIEW
Transdermal drug delivery systems (TDDS) offers a route that by-passes the gut and hence they are more convenient. They are also non-invasive and safer than the other alternatives. The transdermal or the adhesive patches are used to deliver a specific quantity of drug in a controlled release manner through skin for over a long period of time. There are many types of patches like the matrix, membra...
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SYNTHESIS OF QUINOLINE DERIVATIVES BY REACTION OF DIMETHYL(2R,3S,4R)-2-PHENYL-4-(PHENYLAMINO)-1,3,4-TRIHYDROQUINOLINE-2,3-DICARBOXYLATE WITH SOME AMINES
In this work, quinoline derivatives were synthesized from reaction of aniline, benzylaldehyde and dimethylacetylene dicarboxylate (DMAD) in sequent steps to provide quinoline derivative dimethyl (2R, 3S, 4R)-2-phenyl-4-(phenylamino)-1, 3, 4-trihydroquinoline-2,3-dicarboxylate (12). Compound (12), was reacted with some amines such as hydrazine hydrate, urea, thiourea, ethylenediamine, diaminoprop...
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HPMC BASED EXTENDED-RELEASE MATRIX TABLETS OF AN ANTI-PSYCHOTIC DRUG BY DRY GRANULATION METHOD
The aim of the present study was to develop and characterize an oral sustain release drug delivery system for commonly prescribed antipsychotic Quetiapine fumarate. Hydrophilic matrix based tablets using different concentrations of hydroxypropyl methylcellulose (HPMC) viz. K4M CR was developed using dry granulation technique. The prepared tablets were of 400 mg dose and were designed for once- dai...
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ANALYSIS OF TUMOR NECROSIS FACTOR G238A AND G308A GENE POLYMORPHISMS IN TUNISIAN PATIENTS WITH PRESSURE ULCER
Pressure ulcer (PU) is a complex and multifactor disease in which the cellular and molecular mechanisms contributing to risk of a delay in healing. An imbalance between pro-oxidant and antioxidant systems has been suggested to be implicated in the physiopathology of PU. Polymorphisms in TNF-α gene are emerging as key determinants of many diseases. The TNF-α (-238 and -308) G/A single-nucleotide ...
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SPECTROFLUORIMETRIC STUDY ON THE INTERACTION OF IOSARTAN POTASSIUM AND BOVINE SERUM ALBUMIN
The interaction of losartan potassium (LP) with bovine serum albumin (BSA) was studied by fluorescence quenching in combination with UV–Vis spectroscopic method under near physiological conditions. The fluorescence quenching rate constants and binding constants for BSA–LP system were determined at different temperatures. The fluorescence quenching of BSA by LP is due to static quenching and en...
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AN IN-VIVO COMPARATIVE STUDY OF CERIUM TOXICITY IN BULK FORM AND IN NANOPARTICULATE FORM
Scope: In recent years, governments and industries worldwide have invested billions of dollars in nanotechnology research and development, and proponents predict that it will offer numerous benefits to society. Objectives: To evaluate the toxicity of Cerium in nanomaterials and in bulk form in rats by repeated daily oral treatment for 28 days by monitoring the effects on animal and also to assess ...
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