Most Cited
| Year | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | Total |
|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of Published Articles | 238 | 477 | 760 | 633 | 701 | 653 | 622 | 660 | 700 | 706 | 6150 |
| Citations | 2271 | 4232 | 4990 | 2871 | 2238 | 1793 | 1256 | 1045 | 629 | 161 | 21486 |
| Article published in 2015 and 2016: 1275, Citation in 2017 to articles Published in 2015 and 2016- 3049 Projected Impact Factor (2017): 3049/1275 = 2.391 Article published in 2016 and 2017: 1282, Citation in 2018 to articles Published in 2016 and 2017- 2104 Projected Impact Factor (2018): 2104/1282 = 1.641 Article published in 2017 and 2018: 1360, Citation in 2019 to articles Published in 2017 and 2018- 1674 Projected Impact Factor (2019): 1674/1360 = 1.230 |
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IN-SILICO MOLECULAR DOCKING ANALYSIS OF ISOLATED HOMOISOFLAVANONES FROM BULBS OF LEDABOURIA REVOLUTA AS GABAA RECEPTOR INHIBITORS
γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the vertebrate central nervous system (CNS); it activates the GABAA receptors that play a role in epilepsy. Targeting GABAA receptors through specific enhancement of neuronal inhibition involving GABA can be a better mechanism for identification of novel antiepileptic drugs. In this report, screening of novel isolated homoisof...
538
205
CITRULLUS COLOCYNTHIS PHYTOSOMES: DEVELOPMENT AND PHYSIOCHEMICAL CHARACTERIZATION
Present work is aimed at development and characterization of phytosomes, novel drug delivery dosage form used to improve the bioavailability of the drug, containing ethanolic, aqueous, dichloromethane and ethyl acetate extract of Citrullus colocynthis to meet the need for better effectiveness and safety. Required phytosomal formulations were developed using different extracts of Citrullus colocynt...
486
198
A COMBINATORIAL APPROACH TO IDENTIFY NOVEL HIV-PROTEASE (WILD AND MUTANT) INHIBITORS (PIs) USING ZINC DRUG DATABASE
The Human immunodeficiency virus type-1 protease is one of the most important target to highly active anti retrovirus therapy(HAART) for the treatment of all acquired immune deficiency syndrome(AIDS). Protease inhibitor “Darunavir” is most recently included as a PI in the list of HARRT(highly active anti retrovirus therapy), more effective against mutant and wild type simultaneously of Proteas...
1663
778
A STATISTICAL APPROACH TO THE DEVELOPMENT OF FAST DISINTEGRATING TABLETS OF TELMISARTAN USING CO-PROCESSED SUPERDISINTEGRANT
The present investigation deals with fast disintegrating tablets of the model drug (Telmisartan) and to determine the influence of the excipients on physical properties of tablets. Employing a Box Behnken design, concentration of co-processed superdisintegrants (Crosspovidone: sodium starch glycolate) (X1), the concentration of meglumine (X2) and concentration of sodium lauryl sulfate (X3), select...
542
226
EFFECT OF PIPER NIGRUM (LINN.) ON INFERTILITY INDUCED BY ETHIONAMIDE AND PARA AMINO SALICYLIC ACID IN MALE SPRAGUE-DAWLEY RATS
Tuberculosis is a global problem. The tuberculosis is the common cause of male infertility in developing countries due to the use of second-line anti-tuberculosis drugs (ATB). The experiments were conducted at Unique Bio diagnostic Enterprise Veterinary Pathology Laboratory Parel, Mumbai for chemiluminescence immunoassay to study the levels of testosterone in male Sprague-Dawley rats. The histolog...
436
187
FORMULATION AND EVALUATION OF ANTIDIABETIC CAPSULES OF KAEMPFEROL-3-O-Β-D-6”-(P-COUMAROYL) GLUCOPYRANOSIDE EXTRACTED FROM ALLIUM CEPA L.
Allium cepa L. has known potent antidiabetic effects due to several of its constituents, including kaempferol -3-O-β-D-6''-(p-coumaroyl) glucopyranoside (kaempferol). This preliminary work was aimed at preparing oral hard gelatin capsules of kaempferol obtained from Allium cepa L. In order to obtain more potent hypoglycemic activities, lower side effects with good patient compliance over the crud...
935
231
QUANTIFICATION OF A CRUDE EXTRACT FROM HEDERA COLCHICA
Crude extract from the leaves of Hedera colchica (C. Koch) C. Koch proved to have an antiulcer activity in pharmacological experiences. Hederacolchisid F (HCF) is being the chemical marker of this plant, a simple and reliable HPLC method is developed for the quantitative evaluation of the extract using this compound. The chromatographic separation was achieved using an Eclipse XDB-Phenyl c...
2076
1017
DEVELOPMENT AND EVALUATION OF HP-β-CD COMPLEXATION BASED NOVEL OPHTHALMIC GEL FORMULATION OF NEPAFENAC
Nepafenac is an analgesic and anti-inflammatory drug, used in post-operative ocular pain and presently available in the market in the form of 0.1% ophthalmic suspension eye drop due to aqueous insolubility of the drug. The present formulation is not only poor patient compliant due to suspension form but also suffers from a short corneal residence and inadequate ocular bioavailability. The objectiv...
692
168
ANTIDIABETIC ACTIVITY AND POTENTIAL MECHANISM OF MUKIA MADERASPATANA LINN. IN RATS INDUCED BY HIGH FAT DIET AND LOW DOSE STZ
To evaluate the anti-diabetic effects of the Mukia maderaspatana Linn. (MML), and to explore the possible mechanism. High-fat diet and STZ (35 mg/kg) induced diabetic rats were administered with MML at two dose levels (200 and 400 mg/kg/day, p.o.) for 21 days. Fasting blood glucose, lipid and lipoprotein levels such as triglyceride (TG), total cholesterol (TC), high-density lipoprotein-cholesterol...
2050
617
HIGH-THROUGHPUT STRUCTURE BASED VIRTUAL SCREENING TARGETING CNS FOR INHIBITED ACETYLCHOLINESTERASE REACTIVATION
Organophosphorus (OP) nerve agents blocks acetylcholinesterase and do not allow the degradation of acetylcholine. Post-treatment of organophosphate poisoning involves the treatment with oxime reactivators as an antidote, which will dephosphorylate the phosphate bond between enzyme and nerve agent. Due to CNS permeability failure of these oximes, the introduction of low molecular non-oximes has bec...
467
156