Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
COMPARATIVE EVALUATION OF PIOGLITAZONE HCL AND GLICLAZIDE -LOADED HPMC-PVA BLEND PATCHES
Transdermal drug delivery system (TDDS) involving HPMC-PVA patches were prepared as matrix-dispersion system with Pioglitazone HCl (PH) or Gliclazide (GZ) and drug release pattern from these patches were evaluated in-vitro as well as in-vivo. It has been found that 82.41% of Pioglitazone HCl and 70.12% of Gliclazide were released in-vitro in the period of 12 hours and the release patterns was zero...
5041
2034
EFFECT OF DIFFERENT EXCIPIENTS ON THE RELEASE OF NORETHISTERON ACETATE FROM CHITOSAN-SODIUM ALGINATE POLYMERIC IMPLANTS
Biodegradable polymeric implant offers a novel approach for sustained drug delivery that provides an option to the patient of avoiding surgical retrieval of implant post-use. Chitosan, a biodegradable polymer extracted from the hard outer skeleton of shellfish, is used nowadays in many pharmaceutical applications (ophthalmic, nasal, sublingual, buccal, periodontal, gastrointestinal, colon-specific...
4967
1991
LIGAND BASED PHARMACOPHORE MODEL DEVELOPMENT FOR ANTI ANDROGEN RECEPTOR DRUGS FOR TREATING PROSTATE CANCER
The computational modeling and high throughput screening techniques have been used to identify small molecules that specifically target functional surface sites of the androgen receptor in Prostate cancer. Pharmacophore modeling, Virtual screening, docking based analyses is used for development of new chemical entities. The purpose of the current work is to establish pharmacophore model for the FD...
4960
2003
A STUDY ON THE EFFECT OF VIRGIN COCONUT OIL ON BENZO(A)PYRENE INDUCED GASTRIC NEOPLASIA IN MICE.
Objective: The present investigation is focused on detecting anti-carcinogenic potential of virgin coconut oil. Methods: The virgin coconut oil (VCO) from coconut endosperm was prepared by cold compression method. It was examined then for cytotoxicity by cell exclusion studies using trypan blue dye. Chemical carcinogenesis method using benzopyrene was used to study the anticarcinogenecity of VCO. ...
6729
1788
POLY (METH) ACRYLATES NANOSPHERES OF CENTRALLY ACTING ANALGESIC DRUG FOR POSTOPERATIVE PAIN: IN-VITRO AND IN-VIVO CHARACTERIZATION STUDY
Postoperative pain management is prerequisite element for care of surgical patient. Objective of this study was to develop and evaluate nefopam hydrochloride loaded poly (meth) acrylates nanospheres (NFH-NS) for post-incisional pain treatment. Nefopam hydrochloride (NFH) is a centrally acting, non-opioid analgesic exclusive for treatment of post-incisional pain. NFH-NS were fabricated using eudrag...
3656
1483
QUANTITATIVE DETERMINATION OF DRUGS IN BULK AND TABLET FORM BY USING TETRACYANOETHYLENE
The present work narrates UV-Visible spectrophotometric methods have been developed for the determination of selected drugs viz., Lamotragine (LMT), Venlafaxine hydrochloride(VFX), Valacyclovir hydrochloride(VCL) and Ractopamine hydrochloride(RAC) in bulk and their pharmaceutical dosage forms by using Tetracyanoethylene (TCNE) as reagent. These methods have been developed based on the formation of...
4503
1550
HIGH FREQUENCY DIRECT SOMATIC EMBRYOGENESIS FROM THE JUVENILE SHOOT BUDS OF CHLOROPHYTUM BORIVILIANUM SANT. ET FERNAND AND PRODUCTION OF ARTIFICIAL SEEDS
The study presents a protocol for mass propagation of Chlorophytum borivilianum through direct somatic embryogenesis. Direct somatic embryos occurred on the surface of juvenile shoot bud sprouts cultured on Murashige and Skoog medium supplemented with 5 mg L-1 BAP, yielding a high frequency of direct somatic embryos. On the other hand, a much lower concentration of BAP (0.5 mg L-1) led to th...
4644
1773
IN-VITRO ANTIMICROBIAL ACTIVITY OF CRUDE EXTRACT OF FICUS ARNOTTIANA MIQ. LEAVES (MORACEACE): AN ETHNOMEDICINAL PLANT
This study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaves of Ficus arnottiana Miq. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of ethyl acetate, methanol and aqueous extracts of leaves of Ficu...
4708
1895
TREATMENT WITH GLIPTINS AND STUDY OF THE VARIATIONS IN SERUM AMYLASE AND SERUM LIPASE LEVELS IN TYPE 2 DIABETES MELLITUS
Objective: To observe the variations in levels of serum amylase and serum lipase, in patients with type 2 DM after treatment with DPP-4 inhibitors. METHODS: Under this study, 174 Type 2 diabetes mellitus patients were analysed for variations in levels of exocrine pancreatic enzymes after use of dipeptidyl peptidase (DPP) 4 inhibitors. The effect was compared with those under treatment with other o...
5347
2039
SCREENING OF SOY LECTIN: AS NEW ERA CANCER HEALING AGENT
The lectins are glycoproteins or sugar binding proteins of non-immune origin but are barred from sugar binding antibodies and enzymes. Lectins are isolated and purified from seeds of Glycine max by soxhlet extraction and dialysis. These collected crude lectins were centrifuged till pH is shifted downward to optimal pH for coprecipitation. Filtration of the same carried out on a Buchner funnel with...
5224
1879