Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
FORMULATION AND DEVELOPMENT OF HYDROGEL CONTAINING TRIAMCINOLONE ACETONIDE LOADED NANOSPONGES
The ideal of the exploration is to formulate hydrogel containing nanosponges of Triamcinolone acetonide for the treatment of Psoriasis. Psoriasis is presently treated with a numerous of topical and systemic remedies. Numerous of these treatments, still, are costly and involve adverse effects, similar as immunosuppression. As a result, there is a need to develop curatives that are effective, have l...
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EVALUATION OF CO-ADMINISTRATION OF MURRYA KOENIGII LEAVES AND MOMORDICA CHARANTIA FRUITS ON ANTIULCER ACTIVITY IN EXPERIMENTALLY INDUCED ULCERS IN RATS
In this study, the preventive and protective potentials of Murray koenigii (MK) leaves and Momordica charantia (MC) fruit extracts against experimentally induced peptic ulcers in Wistar rats were evaluated. Rats were divided into six experimental groups – normal (saline), control (ulcers), pretreatment with MC extract (fresh fruit juice, 500ml/kg), MK extract (400mg/kg)or both, and pretreatment ...
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MOLECULAR CHARACTERISATION AND ANTAGONISTIC POTENTIAL OF MANGROVE STREPTOMYCES ISOLATED FROM COASTAL REGIONS OF ANDHRA PRADESH, INDIA
The main aim of the present study is to isolate and identify potent actinobacteria from mangrove sediments of SPSR Nellore district, Andhra Pradesh, India along with their antimicrobial activity. The samples collected were initially pretreated with calcium carbonate followed by dry heating. Dilution plate technique was employed to isolate actinobacteria employing two selective media viz. yeast ext...
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ANTIDYSLIPIDEMIC EFFECT OF EUGENIA JAMBOLANA EXTRACT ON HIGH FAT DIET INDUCED DYSLIPIDEMIA IN RATS
Antidyslipidemic activity of extract of Eugenia jambolana (EJ, Jamun fruit) in adult Charles Foster rats of both sexes was studied and compared with that of Atorvastatin (Atorva). 4 groups were made [Gp 1- Control group (no drug), only high fat diet (HFD); Gp 2- HFD +EJ (evaluation of role of EJ in the prevention of dyslipidemia); Gps 3 & 4-only HFD]. This was the phase of disease production, ...
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NOVEL PYRIMIDINE DERIVATIVES AS POTENTIAL ANTIMICROBIAL AGENTS: SYNTHESIS AND BIOLOGICAL EVALUATION
The pyrimidine scaffold found in many bioactive drugs; some commercially available drugs containing at least one pyrimidine ring in their structure. The literature survey reveals that replacement of 1H-pyrazole of pyrazolo [3,4-d] pyrimidine ring system by other bioactive moieties drastically alters its pharmacological properties. Prompted by the varied biological activities of pyrazolopyrimidine ...
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ANXIOLYTIC AND ANTIDEPRESSANT ACTIVITY OF PETAL OF CROCUS SATIVUS VAR. ‘CASHMERIANUS’
Crocus sativusvar. ‘cashmerianus’ (Iridaceae)is worldwide known as “Saffron” contains than volatile and aroma-containing compounds mainly terpenes, terpene alcohol, and their esters. The bitter taste and a hay-like fragrance of saffron are due to presence picrocrocin and safranal. Traditional anxiolytic and antidepressant effects of C. sativus var. ‘cashmerianus’ was evaluated using su...
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IMPURITY PROFILING METHOD DEVELOPMENT AND VALIDATION FOR METFORMIN HCL AND VILDAGLIPTIN FROM COMBINATION TABLET DOSAGE FORM BY RP-HPLC COUPLED WITH UV/PDA DETECTOR
A precise, accurate, robust method was developed for quantitative estimation of related impurities of Metformin HCL and Vildagliptin from combination tablet dosage form. The mixture of ammonium dihydrogen orthophosphate and octane sulfonic acid sodium salt buffer at pH 4 was used as mobile phase A and mixture of methanol and buffer in the ratio of95:5 used as a mobile phase B. The mobile phase was...
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FIVE-YEAR ANTIMICROBIAL SUSCEPTIBILITY TRENDS AMONG PATHOGENS CAUSING URINARY TRACT INFECTION FROM A TERTIARY CARE HOSPITAL IN HIMACHAL PRADESH, INDIA
Introduction: Urinary tract infection is the most frequent infection reported worldwide till now. To better understanding regarding epidemiology and emerging antimicrobial resistance among bacterial uropathogens, we studied the demographic distribution and antibiotic susceptibility pattern of microorganisms causing UTI in our local hospital-based study. Materials and Methods: We analysed the ret...
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DISSOLUTION ENHANCEMENT OF ROSUVASTATIN CALCIUM BY USING VARIOUS GENERATIONS OF HYDROPHILIC POLYMERS: A COMPARATIVE STUDY
Oral administration is the preferred route of drug administration owing to its convenience, patient compliance, and cost-effectiveness. The study aspired to augment the solubility and dissolution rate of Rosuvastatin calcium (RST) by using the solid dispersion (SD) technique with various generations of hydrophilic polymers. Hot melt and solvent evaporation methods were employed to prepare SD using...
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CLINICAL EVALUATION OF EFFICACY OF MUNḍIJ AND MUSHIL THERAPY IN THE MANAGEMENT OF RHEUMATOID ARTHRITIS
Objective: To study the anti-arthritic effect of a Unani regimen comprising of Munḍij wa Mushil therapy along with Habb-e-Gul-e-Aak and to propose a safe and alternative therapy for RA. Materials and Methods: In this clinical trial, 30 diagnosed patients of RA fulfilling the inclusion and exclusion criteria were recruited and randomly distributed into two groups A&B with 20 patients in the t...
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