Most Cited
Year | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | Total |
---|---|---|---|---|---|---|---|---|---|---|---|
No. of Published Articles | 238 | 477 | 760 | 633 | 701 | 653 | 622 | 660 | 700 | 706 | 6150 |
Citations | 2271 | 4232 | 4990 | 2871 | 2238 | 1793 | 1256 | 1045 | 629 | 161 | 21486 |
Article published in 2015 and 2016: 1275, Citation in 2017 to articles Published in 2015 and 2016- 3049 Projected Impact Factor (2017): 3049/1275 = 2.391 Article published in 2016 and 2017: 1282, Citation in 2018 to articles Published in 2016 and 2017- 2104 Projected Impact Factor (2018): 2104/1282 = 1.641 Article published in 2017 and 2018: 1360, Citation in 2019 to articles Published in 2017 and 2018- 1674 Projected Impact Factor (2019): 1674/1360 = 1.230 |
EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF TILIACORA ACUMINATA EXTRACT IN RATS
Inflammation is part of the body's immune response. There can be four primary indicators of inflammation: pain, redness, heat or warmness and swelling. Plants have the ability to synthesize a wide verity of phytochemical compounds as secondary metabolites which shows anti-inflammatory activity. The anti-inflammatory activity of ethanol extract of Tiliacora acuminata stem and leaf was evaluated usi...
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A STATISTICAL APPROACH TO THE DEVELOPMENT OF FAST DISINTEGRATING TABLETS OF TELMISARTAN USING CO-PROCESSED SUPERDISINTEGRANT
The present investigation deals with fast disintegrating tablets of the model drug (Telmisartan) and to determine the influence of the excipients on physical properties of tablets. Employing a Box Behnken design, concentration of co-processed superdisintegrants (Crosspovidone: sodium starch glycolate) (X1), the concentration of meglumine (X2) and concentration of sodium lauryl sulfate (X3), select...
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EFFECT OF PIPER NIGRUM (LINN.) ON INFERTILITY INDUCED BY ETHIONAMIDE AND PARA AMINO SALICYLIC ACID IN MALE SPRAGUE-DAWLEY RATS
Tuberculosis is a global problem. The tuberculosis is the common cause of male infertility in developing countries due to the use of second-line anti-tuberculosis drugs (ATB). The experiments were conducted at Unique Bio diagnostic Enterprise Veterinary Pathology Laboratory Parel, Mumbai for chemiluminescence immunoassay to study the levels of testosterone in male Sprague-Dawley rats. The histolog...
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IN VITRO AND IN VIVO CHARACTERIZATION OF GLIMEPIRIDE MICROPARTICLES
In the present investigation, controlled release microparticles of Glimepiride were prepared by emulsion solvent evaporation technique using cellulose acetate as release retardant polymer. The microparticles were evaluated for In-Vitro release study and In-Vivo evaluation. The microparticles were subjected to In-vitro release studies by employing 7.8 pH phosphate buffer as dissolution medium. The ...
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FORMULATION AND EVALUATION OF ANTIDIABETIC CAPSULES OF KAEMPFEROL-3-O-Β-D-6”-(P-COUMAROYL) GLUCOPYRANOSIDE EXTRACTED FROM ALLIUM CEPA L.
Allium cepa L. has known potent antidiabetic effects due to several of its constituents, including kaempferol -3-O-β-D-6''-(p-coumaroyl) glucopyranoside (kaempferol). This preliminary work was aimed at preparing oral hard gelatin capsules of kaempferol obtained from Allium cepa L. In order to obtain more potent hypoglycemic activities, lower side effects with good patient compliance over the crud...
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DEVELOPMENT AND EVALUATION OF HP-β-CD COMPLEXATION BASED NOVEL OPHTHALMIC GEL FORMULATION OF NEPAFENAC
Nepafenac is an analgesic and anti-inflammatory drug, used in post-operative ocular pain and presently available in the market in the form of 0.1% ophthalmic suspension eye drop due to aqueous insolubility of the drug. The present formulation is not only poor patient compliant due to suspension form but also suffers from a short corneal residence and inadequate ocular bioavailability. The objectiv...
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HIGH-THROUGHPUT STRUCTURE BASED VIRTUAL SCREENING TARGETING CNS FOR INHIBITED ACETYLCHOLINESTERASE REACTIVATION
Organophosphorus (OP) nerve agents blocks acetylcholinesterase and do not allow the degradation of acetylcholine. Post-treatment of organophosphate poisoning involves the treatment with oxime reactivators as an antidote, which will dephosphorylate the phosphate bond between enzyme and nerve agent. Due to CNS permeability failure of these oximes, the introduction of low molecular non-oximes has bec...
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CONSERVED WATER MIMIC INHIBITOR DESIGN FOR hIMPDH (INOSINE MONOPHOSPHATE DEHYDROGENASE): MD SIMULATION AND DOCKING STUDIES OF IMP-ANALOGS
Inosine Monophosphate Dehydrogenase (IMPDH) plays a very important role in Guanosine Monophosphate (GMP) biosynthesis. Type I hIMPDH is expressed at lower levels in all cells, whereas type II is especially observed in acute myelogenous leukemia, chronic myelogenous leukemia cancer cells, so it is thought to be an active target for leukemic drug design. MD-simulation studies of the solvated modeled...
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A REVIEW ON NATURAL CHALCONES AN UPDATE
Plants are a valuable source of secondary metabolites. Many phytochemicals are obtained from the plant sources that are used as valuable medicinal agents. Chalcones are one of the important secondary metabolites obtained from many edible plants like foods, vegetables, tea, spices and natural foodstuffs. Chalcones considered as obligate intermediated in flavonoid biosynthesis but they do not accumu...
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ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ESBL PRODUCING BACTERIA FROM URINARY TRACT INFECTION (UTI)
Antibiotics inhibit bacterial cell wall synthesis, protein synthesis or nucleic acid replication. The antibiotic must have access to and bind to its bacterial target site. Whether antibiotic resistance is intrinsic or acquired, the genetic determinants of resistance encode specific biochemical resistance mechanism that may include enzymatic inactivation of the drug, alteration to the structure of ...
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