Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ANTI- CONVULSANT PROFILE OF AQUEOUS EXTRACT OF SAPINDUS LAURIFOLIA IN EXPERIMENTAL ANIMALS
Objective: The aim of the present study was to evaluatethe anti convulsant property of aqueous extract of Sapindus laurifolia in Pentylenetetrazole (PTZ) and MES induced convulsions in experimental models. Materials & Methods: The purpose of this study is to explore the anticonvulsant activity of ethanolic extract of Momordica tuberosa using Pentylenetetrazole and maximal electric shock induce...
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EVALUATION OF ANALGESIC ACTIVITY OF SOME NOVEL SUBSTITUTED L-ARGININE ANALOGUES
A series of novel L-arginine analogues were synthesized characterized and screened for analgesic activity by acetic acid induced analgesia model. The purity of the synthesized compounds has been characterized by various analytical techniques such as UV, FTIR and TLC. The synthesized compounds were evaluated for analgesic activity by acetic acid induced analgesia in mice using paracetamol as the st...
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NIGELLA SATIVA AMELIORATES OXIDATIVE STRESS INDUCED BY DIETHYL PHTHALATE – AN IN VITRO STUDY
The present experiment was designed to assess oxidative stress, if any, caused by diethyl phthalate and its amelioration by Nigella sativa seed extract. For this, the liver and kidney homogenates were treated with different concentrations (10-40 µg/mL) of DEP with or without Nigella sativa seed extract. Lipid peroxidation, a marker for oxidative stress along with total protein content was analyze...
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SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF 3-(1H-BENZO[d]IMIDAZOL-2-YLSULFANYL) METHYL-4-[PHENOXY(PHENYL) ACETAMIDO)-5-MERCAPTO-1,2,4-TRIAZOLE AND RELATED ARYLOXY COMPOUNDS
A series of new 1H-benzo[d]imidazole derivatives of 3, 4-substituted triazole. 3-(1H-Benzo[d]imidazol-2-ylsulfanyl) methyl-4-[phenyloxy(phenylacetamido)]-5-mercapto-1,2,4-triazole and related aryloxy compounds were synthesised, analysed and characterised by FTIR, 1HNMR and elemental analysis. These compounds were screened for antibacterial and antifungal activity. The antibacterial activities were...
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1104
WOUND HEALING AND ANTIOXIDANT POTENTIAL OF CHLOROFORM EXTRACT OF SARACA ASOCA (ROXB.)
The chloroform extracts of S. asoca bark were studied for the wound healing potential. The wound healing activity of S. asoca bark by excision, incision and dead space wound models in albino Wistar rats and antioxidant profile of this bark extract were also studied as there is an increase in the levels of free radicals during the damage of tissue. The parameters like wound contraction, period...
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DEVELOPMENT AND CHARACTERIZATION OF BILAYERD TRANSDERMAL FILM OF DICLOFENAC DIETHYLAMINE
The aim of this research work was to develop and characterise bilayer film and to investigate its potential as slow-release wound healing vehicle. The bilayer is composed of an upper layer impregnated with Diclofenac diethyl amine and a drug-free lower layer, which acted as a rate-controlling membrane. Solvent casting technique was employed to prepare transdermal films. Pre formulation studies are...
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EXPRESSION OF CHICKEN ANEMIA VIRUS VP3 GENE IN HeLa CELLs
Chicken anemia virus (CAV) encodes the protein VP3 also named “apoptin” that specifically induces apoptosis in human tumor cells. In this study, the VP3 gene cloned in p VAX1 plasmid vector was transfected in HeLa cells. The expression of CAV VP3 gene was detected using immunoperoxidase test and indirect fluorescent antibody technique. High level of gene expression was observed in HeLa cell cu...
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ISOLATION OF NATURAL BINDING AGENT FROM EULOPHIA OCHREATA LINDL. AND ITS EVALUATION
Aim and objective: To isolate the natural herbal binding agent from Eulophia ochreata Lindl. and study its evaluation properties using diclofenac as a model drug. Principle: Binders confer structural strength required by tablets during processing, handling, packaging and transportation. A number of plant mucilage, gums/hydrocolloids have been used as binding agents, suspending or emulsifying ag...
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IMMUNOLOGICAL AND MOLECULAR DETECTION OF CHLAMYDIA TRACHOMATIS AMONG WOMEN AT REPRODUCTIVE AGE ATTENDING OMDURMAN MATERNITY HOSPITAL
Chlamydia trachomatis is the most common bacterial sexually transmitted disease. Over 100 million men and women worldwide are infected with Chlamydia at any point in time. The aim of this study to detect the presence of C. trachomatis antibodies and antigen among women on the reproductive age and to study the relationship between the presence of C. trachomatis and age, abortion and ectopic pregnan...
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ISOLATION AND CHARACTERIZATION OF THE CHEMICAL CONSTITUENTS OF STELLARIA MEDIA LINN.
The studies on the constituents of aerial parts of Stellaria media Linn. (Caryophyllaceae) have led to the isolation and characterization of three new compounds ─ (1), (2) and (3). Structure elucidation of the new compounds was carried out using 1H NMR, 13C NMR, Mass spectrometry together with other complementary techniques (UV and IR). The major findings of the study include: Compound 1 was sep...
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