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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Most Cited

CITATIONS REPORT: (Source- Google Scholar)
 
Year 202020212022Total
No. of Published Articles 745760548 2053
Citations 50513611 652
Projected Impact Factor 3.061.510.43  
Total Citations: 43607
 
Title
Views
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Cited
30.

PHARMACOPHORE BASED MODELLING OF PYRIDINE-PYRIMIDINE ANALOGS AS MER TYROSINE KINASES INHIBITORS IN ANTICANCER THERAPY

MER kinase is an important tyrosine-kinase receptor that is associated with a variety of cancers, including mantle cell lymphomas, pituitary adenomas and T-cell acute lymphoblastic leukemia. Identification of new MERTK inhibitors assumes crucial importance. Only one ligand-based pharmacophore model is reported to date for MERTK inhibitors. There are many more molecules with improved enzyme inhibit...

Sandip Wagh * and Vaibhav Wagh

Department of Pharmaceutical Chemistry, SNJB’s SSDJ College of Pharmacy, Neminagar, Chandwad, Nasik, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5905-15

5905-5915

326

149

31.

FORMULATION AND EVALUATION OF PROPRANOLOL HYDROCHLORIDE ORAL DISINTEGRATING TABLETS

Background and purpose of the study: Propranolol hydro-chloride beta-adrenergic receptor antagonist utilized in the treatment of high blood pressure, atrial fibrillation, myocardial infarction, angina and migraine headaches. The pharmacokinetic parameters make Propranolol hydrochloride an appropriate candidate for oral disintegrating tablets. This work aims to develop orally disintegrating tablets...

M. Keerthana, L. Smitha and S. Pavani *

Department of Pharmaceutics, Vaagdevi College of Pharmacy, Hanamkonda, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5916-21

5916-5921

742

231

32.

STUDIES ON ANTIMICROBIAL ACTIVITY OF HIBISCUS SPECIES OF KARNATAKA AGAINST CLINICAL ISOLATES

Antimicrobial activity of the various species of Hibiscus like Hibiscus sabdariff, Hibiscus rosa-sinensis, Hibiscus trionum, Hibiscus cannabinus, Hibiscus mutabilis against various pathogens like Staphylococcus aureus, E. coli, Bacillus subtilis, Streptococcus species, Salmonella typhimurium, Klebsiella pneumonia, Pseudomonas aeruginosa, Serratia marcescens, were studied with the help of agar well...

H. G. Pavithra Kumari * and P. N. Narase Gowda

Tumkur University, Tumkur, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5922-32

5922-5932

368

178

33.

AN OPTIMIZED HERBAL FORMULA DIMINISHES CCL4-INDUCED HEPATOTOXICITY IN RATS BY INHIBITION OF LIPID PEROXIDATION AND P53-MEDIATED APOPTOSIS

Introduction: In this present study, the heaptoprotective effect of an optimized herbal formula (HF) was evaluated against carbon tetrachloride (CCl4)-induced liver injuries in rats. Methods: In-vitro antioxidant activity of the HF was evaluated by reducing power, lipid peroxidation, and DPPH scavenging assays. Hepatoprotective activity of HF (100, 200 and 400 mg/kg b.w) was evaluated against CCl4...

Manjir Sarma Kataki * and Dr. Bibhuti Bhusan Kakoti

Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5933-42

5933-5942

312

125

34.

A SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM FOR IMPROVEMENT IN ORAL BIOAVAILABILITY OF NIMODIPINE: IN-VIVO EVALUATION

The current research involves the study of a Nimodipine self-nanoemulsifying drug delivery system (SNEDDS) with improved bioavailability and solubility. Fifteen formulations of Nimodipine SNEDDS were prepared prior to evaluation of particle size, emulsification time, percentage drug release, percentage transmittance, thermodynamic stability and in-vitro drug release. The formulation F13 was chosen...

S. Srikanth Reddy and G. Suresh *

Career Point University, Kota, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5943-48

5943-5948

328

168

35.

FORMULATION AND EVALUATION OF NANOSUSPENSION OF ROSUVASTATIN FOR SOLUBILITY ENHANCEMENT BY QUALITY BY DESIGN APPROACH

Rosuvastatin is an antihyperlipidemic agent belonging to BCS class II Drugs with low aqueous solubility and high permeability. Objective: To formulate Rosuvastatin nanosuspension by Emulsification solvent diffusion technique by QbD approach and its evaluation. A 2² factorial design was employed to study the effect of independent variables [SLS (X1) and amount of PVP K -30(X2)] and dependent varia...

B. Sharannavar * and S. Sawant

KLE College of Pharmacy, Belagavi, KLE Academy of Higher Education and Research, JNMC Campus, Nehru Nagar, Belagavi, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5949-58

5949-5958

1002

304

36.

QUANTITATIVE AND QUALITATIVE PHYTOCHEMICAL ANALYSIS IN BARK OF NOTHOPEGIA RACEMOSA (DALZ.) RAMAM. COLLECTED FROM GADIKALLU, SHIMOGGA, KARNATAKA

Plants are a source of bioactive compounds produced by different parts of the plant, maybe bark, leaves, flowers, roots, fruits, and seeds, during metabolic activities. These secondary metabolites may have protective and disease preventive properties, hence used by Traditional practioner to treat various ailments. Most plants of the Western Ghats of India remain unknown, poorly understood or unest...

K. S. Geethanjali and D. Poornima *

Department of Biotechnology, University College of Science, Tumkur University, B. H. Road, Tumakuru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5959-67

5959-5967

356

195

37.

EFFICACY OF DRUGS IN DRUG-RESISTANT TUBERCULOSIS: A RETROSPECTIVE OBSERVATIONAL STUDY

Introduction: Drug-resistant tuberculosis (DR-TB) emerged from the time anti-tuberculosis drugs were discovered and used. It has become a formidable obstacle in the eradication of tuberculosis. India is in second position after China with tuberculosis, where about 20% of patients with DR-TB were not treated due to inappropriate coordination and diagnostic facilities. Method and Materials: A retros...

Joicy Jose, Leya P. Babu, Nimmy Robin, Johnson V. Babu and Shaji George *

Department of Pharmacy Practice, Nirmala College of Pharmacy, Muvattupuzha, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5968-73

5968-5973

310

110

38.

THE AFRICAN BAOBAB SEED OIL AND ITS POTENTIAL FOR SOLUBILISING POORLY SOLUBLE DRUGS

Most lipids used in solubilizing poorly soluble drugs are synthetic or semi-synthetic. In this study, the African Baobab seed oil (natural oil) was investigated for its potential in solubilizing poorly soluble drugs in a microemulsion formulation. Oil was extracted from untreated seeds by hydraulic pressing. Physicochemical characteristics of the oil were determined. The solubility of Furosemide, ...

A. D. Aberimah, R. Johnson *, M. T. Bayor, N. Kuntworbe and F. W. A. Owusu

Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

DOI: 10.13040/IJPSR.0975-8232.12(11).5974-86

5974-5986

514

183

39.

DEVELOPMENT AND VALIDATION OF TLC-DENSITOMETRIC METHOD FOR ESTIMATION OF FLUPIRTINE MALEATE AND ITS FORMULATIONS

A simple, precise, accurate, and reliable high-performance thin-layer chromatographic method has been developed and validated for the analysis of flupirtine maleate in capsule dosage form. Identification and analysis were performed on 10 cm × 10 cm layer thickness 0.2 mm, precoated silica gel G60-F254 aluminum sheet, prewashed with methanol, and dried in an oven at 50 °C for 5 min. Ethyl acetate...

A. Suneetha *, B. Chandra Sekhar and K. Raja Rajeswari

Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Amaravathi Road, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(11).5987-91

5987-5991

329

121