Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
INFLUENCE OF THE SUPERDISINTEGRANTS IN NIFEDIPINE RELEASE FROM OSMOTIC PUSH-PULL TABLETS
Push-pull osmotic pumps are controlled drug delivery systems for drugs with a broad range of solubilities; especially drugs that are poorly water-soluble. The aim of the present study was to evaluate the performance of the superdisintegrants (SD), crospovidone (CPVP), croscarmellose sodium (CS), and sodium starch glycolate (SSG), in push-pull tablets containing Nifedipine (NP) as a model drug. We ...
3655
1401
EFFECT OF CO-PROCESS EXCIPIENTS IN FORMULATION OF ODTs USING A MODEL DRUG
Different types of excipients were compared, in terms of their effect in (oral disintegrated tablets-ODTs) to optimize drug delivery and manufacturability. Therefore, the influence of excipients on the quality of ODTs was investigated by formulating and evaluate ODTs using an equal dose of water-soluble Baclofen (B) and poorly water-soluble Meloxicam (M) as model drugs. ODTs of both drugs were pre...
3380
1549
DOSE DEPENDENT ANTIDIABETIC ACTIVITY OF HYDRO-METHANOLIC EXTRACT (3:2) OF FLOWER OF M. BALBISIANA IN STREPTOZOTOCIN INDUCED DIABETIC MALE RAT
Background: Musa balbisiana Colla (Musaceae family) is used as folkloric medicine throughout India. Objective: To search out the potent dose of a hydro-methanolic extract of Musa balbisiana flower for antidiabetic and antioxidative activities in streptozotocin-induced diabetic rat. Material and Methods: The extract of the said plant part was administered orally at the dose of 5, 10 or 20 mg /100 g...
2674
1035
A STUDY OF POSSIBLE PROTECTION BY NEFIRACETAM ON ESLICARBAZEPINE INDUCED MEMORY IMPAIRMENT IN TEMPORAL LOBE EPILEPSY
Memory impairment (MI) is commonly seen in epilepsy and is at times aggravated by antiepileptic therapy. Recent studies reported that co-administration of nootropic agent with an antiepileptic drug (AED) might decrease the MI. This study was designed to evaluate MI activity of Eslicarbazepine (ESL) in temporal lobe epilepsy (TLE) and to assess the protective effect of Nefiracetam (NEF) which is a ...
2013
698
IN-VIVO APPRAISAL OF PHARMACOLOGICAL ACTIVITY OF BACOPA MONNIERI AND ITS HPLC ANALYSIS FOR BACOSIDE A
Bacopa monnieri is a herb, known to possesses various pharmacological and medicinal properties. Aim: The objective of the study was to analyse the activity of Bacopa monnieri as an antipyretic, analgesic and anti-ulcerogenic agent. Methods: Indomethacin was used as the standard of comparison for this study. Animals were arbitrarily separated into three groups of six animals in each group. The firs...
2038
715
RECONSTITUTION OF ORAL ANTIMALARIAL SUSPENSIONS: AN UNRECOGNIZED FACTOR IN ANTIMALARIAL DRUG RESISTANCE
Malaria is a foremost universal public health problem, especially in the African region and development of resistance to the older and new generation malaria therapy, has become a persistent health threat requiring urgent solutions. This study intended to assess the ability of human subjects to accurately reconstitute antimalarial dry suspensions according to the manufacturer’s instructions. Two...
2867
1046
ANTIDIABETIC AND LIPID LOWERING EXTENUATING IMPACT OF GLYCINE MAX LEAVES (SOYABEAN) IN TYPE II DIABETES MELLITUS SUBJECTS
Diabetes mellitus is possibly the world’s largest growing metabolic disease. Currently, a challenge is to identify such healthy foods that remain in the realms of obscurity and to establish them as functional foods to prevent the progression of metabolic complications. Glycine max is indigenous to India and is used extensively in the traditional system of medicine to treat diabetes, reduces coro...
1990
808
IN-VITRO NEUROPROTECTIVE ACTIVITY OF SILIBININ AGAINST MPTP (1-METHYL-4-PHENYL-1, 2, 3, 6-TETRAHYDROPYRIDINE) INDUCED NEUROTOXICITY MODEL
In the present study, we examined the effect of Silibinin on the accumulation of oxidative stress induced by MPTP by in-vitro. After decapitation, healthy rat brain was removed rapidly from the skull and rinsed with cold artificial cerebrospinal fluid (ACSF) which has been equilibrated with 95% O2 / 5% CO2 gas mixture. Group I brain was incubated in CSF serve as normal, Group II lenses brain was i...
1634
694
RADIOPROTECTIVE EFFECT OF OPUNTIA ELATIOR ON BLOOD OF SWISS ALBINO MICE
The modulatory effect of Opuntia elatior stem extract was studied in Swiss albino mice at dose 6 Gy of gamma radiation. Four groups were divided in the presence (experimental) or absence (control) of Opuntia extract 10 mg/kg body wt.) to observe hematological alterations. Four groups are Group I without any treatment as control, Group II treated with 10 mg/kg body weight dose of plant Opuntia elat...
1643
732
ACUTE ORAL TOXICITY AND NEUROBEHAVIOURAL TOXICOLOGICAL EFFECTS OF METHANOLIC EXTRACT OF CHRYSOPHYLLUM PERPULCHRUM IN RATS
This study aimed to investigate the acute toxicity of methanolic extract of Chrysophyllum perpulchrum on biochemical, behavioral and histopathological variation in male Wistar rats. Acute toxicity of the methanol extract of Chrysophyllum perpulchrum was carried out on 36 male rats using different doses of the extract ranging from 500 to 2000 mg/kg body weight. Behavioral tests were used to determi...
1787
807