APPLICATION OF THE INFORMATION TECHNOLOGIES IN EARLY PREDICTING THE SEVERITY OF ATOPIC DERMATITIS IN CHILDREN
The application of mathematically based prognostic software is a rational and promising approach to determining disease prognoses. In our research, we identified indicators as prognostic criteria for the development of atopic dermatitis (AD). Our research involved 260 healthy children and 268 newborns with AD. To select the risk factors for predicting the formation of AD, initially, variation and ...
HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY OF MORINGA OLEIFERA LEAF POWDER IN ALLOXAN-INDUCED DIABETIC RABBITS
The present study was carried out to investigate the hypoglycemic and hypolipidemic effect of Moringa oleifera leaf powder (MO) in alloxan-induced diabetic rabbits by administering oral doses (100, 200, and 400 mg/kg body weight). Diabetes was induced intravenously into rabbits with a single dose of alloxan (150 mg/kg). Diabetic rabbits were treated with MO (100, 200, and 400 mg/kg) and Glibenclam...
Pioglitazone is an oral anti-diabetic agent used in treating class – II diabetes mellitus. T1/2of pioglitazone was 3-6 hrs and is eliminated rapidly. Hence sustained release is needed to prolong its duration of action and to increase its oral bioavailability. The study's main aim was formulation and evaluation of an in-situ gel system of pioglitazone to increase its bioavailability as a convenie...
CLINICAL DIAGNOSIS AND SAFETY OF VILDAGLIPTIN VERSUS GLIMEPIRIDE WITH METFORMIN OVER PATIENTS OF TYPE-2 DIABETES MELLITUS
The aim of the study to compare the efficacy of vildagliptin (50 mg) and glimepiride (2 mg) metformin (500 mg) for type-2 diabetes mellitus. Vildagliptin and glimepiride are found to be regulated the blood plasma glucose by stimulating beta cell in the pancreas. The treatment course duration of 34 weeks comparative observational study was conducted over 160 patients with type-2 diabetes mellitus w...
IN-SILICO DESIGN AND COMPUTATIONAL STUDY OF NOVEL QUINAZOLIN-4-ONE DERIVATIVES AS POTENTIAL AFFINITY WITH EGFR FOR ANTICANCER ACTIVITY
Molecular object precise healing designed for the malignancy be unrelated as of the predictable therapy, as well as radio healing in conditions of selectivity and specificity target to the malignant tyrosine kinase, is well-thought-out additional shows potential molecular intention for invention and expansion of the new cytotoxic drug molecules. Epidermal growth factor receptor is overexpression i...
PROTECTIVE ACTIVITY OF THE METHANOLIC EXTRACT AND ITS SOLVENT FRACTIONS OF THE FRUITS OF SOLANUM NIGRUM (MAKO) ON GENTAMICIN-INDUCED NEPHROTOXICITY IN ALBINO RATS
Objective: Mako (Solanum nigrum L.), Black Nightshade in English, belongs to the family Solanaceae is an edible plant. The whole plant is used as a green source of vegetables and berries as a fruit. It is a good source of antioxidant and has potent anti-inflammatory, diuretic, lithotriptic, wound healing properties. Unani scholars have advocated the berries to treat many renal ailments, including ...
Hugonia mystax is a woody evergreen plant that grows in the dry forest areas of India and Sri Lanka. Often found in the forests of Kerala and Tamil Nadu in southern India. It is locally known as modirakanni (tamil) and kamsamaraha and tribals from Tamil Nadu, India, have used it in primary health care. The plant parts are used ethnobotanically to treat rheumatism, skin diseases and inflammations, ...
PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF EXTRACTS OF AZADIRACHTA INDICA A. JUSS (MELIACEAE) (CÔTE D’IVOIRE)
The purposes assigned to this work are the phytochemical screening of certain phytoconstituents, the estimation of the antioxidant and antibacterial activities of extracts of Azadirachta indica A. Juss. The selective extracts obtained from the aqueous decocts were used to establish the chromatographic profile of the various extracts. As for the crude aqueous extracts, they were used to carry out t...
The present study is focused on exploring the chemical components of the leaves, stem, root, and seeds of potential weed Digera arvensis. The plant has high nutritional value and therapeutic significance with prospective pharmacological activities. The various parts of the plants, i.e., leaves, stems, roots and seeds, were extracted using polar solvent ethanol. The preliminary phytochemical invest...
For the last few centuries, the leaves of Stevia rebaudiana have been used as an efficient substitute for sugar due to its sweetness and almost negligible Glycemic effects. The study concentrates on the pharmacognostic aspects and other anatomical characteristics of the leaves. The study is performed on the plant leaves collected from the medicinal plant garden of Birla Institute of Technology, Me...