Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
THE AFRICAN BAOBAB SEED OIL AND ITS POTENTIAL FOR SOLUBILISING POORLY SOLUBLE DRUGS
Most lipids used in solubilizing poorly soluble drugs are synthetic or semi-synthetic. In this study, the African Baobab seed oil (natural oil) was investigated for its potential in solubilizing poorly soluble drugs in a microemulsion formulation. Oil was extracted from untreated seeds by hydraulic pressing. Physicochemical characteristics of the oil were determined. The solubility of Furosemide, ...
2071
1381
DEVELOPMENT AND VALIDATION OF TLC-DENSITOMETRIC METHOD FOR ESTIMATION OF FLUPIRTINE MALEATE AND ITS FORMULATIONS
A simple, precise, accurate, and reliable high-performance thin-layer chromatographic method has been developed and validated for the analysis of flupirtine maleate in capsule dosage form. Identification and analysis were performed on 10 cm × 10 cm layer thickness 0.2 mm, precoated silica gel G60-F254 aluminum sheet, prewashed with methanol, and dried in an oven at 50 °C for 5 min. Ethyl acetate...
1612
782
SYNTHESIS, SPECTROSCOPIC INVESTIGATION AND BIOEFFICACY OF SOME NOVEL SCHIFF BASE METAL (II) COMPLEXES
Two monobasic bidentate ligands L1H [2-(5-Bromo-2-dihydro-2-oxo-1H-indol-3-ylidene)hydrazine-carboxamide] and L2H [2-(5-Bromo-2-dihydro-2-oxo-1H-indol-3-ylidene)hydrazinecarbothioamide] were synthesized by the condensation of [2-(5-Bromo-2-dihydro-2-oxo-1H-indol-3-ylidene) with semicarbazide and thiosemcarbazide, which formed a series of complexes with cobalt(II) and nickel(II). The ligands ...
1619
850
AN HPLC WITH PHOTODIODE ARRAY DETECTION METHOD FOR SIMULTANEOUS DETERMINATION OF ENROFLOXACIN AND ITS ACTIVE METABOLITE, CIPROFLOXACIN, IN CHICKEN MEAT
A reverse-phase liquid chromatography (LC) method was developed for the simultaneous estimation of enrofloxacin and its active metabolite ciprofloxacin residues in chicken meat. These two fluoroquinolones were extracted from homogenized tissues with phosphate buffer under acidic conditions, followed by acetonitrile. The isocratic LC analysis was performed on Phenonmenax, C18 RP column (250 × 4.6 ...
1789
896
EFFECT OF HELLENIA SPECIOSA (J. KOENIG) S. R. DUTTA ON HEMATOLOGICAL INDICES OF ALLOXAN INDUCED DIABETIC RATS
The present study aimed to evaluate the effect of crude leaf extract of Hellenia speciosa on hematological parameters of alloxan-induced diabetic rats. The study was carried out using alloxan model of diabetes for a period of 28 days and at the end of the treatment rats were sacrificed and blood samples were collected for the estimation of hematological parameters. The results showed that the whit...
1637
898
A VALIDATED STABILITY-INDICATING RP-HPLC METHOD FOR DETERMINATION OF ESMOLOL HYDROCHLORIDE AND ITS RELATED IMPURITIES
Esmolol Hydrochloride belongs to the class II anti-arrhythmic drugs. Due to composite compositions and low reproducibility, challenges are still warranted for the systematic method development for related substances and identification of its acid degradation products. Development, validation and characterization of RP-HPLC stability-indicating method for the quantitative analysis of two impurities...
2254
1936
DEVELOPMENT AND VALIDATION OF SPECTROSCOPIC METHODS FOR THE SIMULTANEOUS ESTIMATION OF RASAGILINE AND RILUZOLE
In the present study, an effort has been made to estimate Rasagiline and Riluzole simultaneously in their bulk and physical mixture by UV-Visible spectrophotometric methods. The methods developed are precise, reliable simultaneous equations and area under the curve (AUC) method. The absorption maxima in the simultaneous equation method are 265.20 nm and 263.40 nm, respectively, for rasagiline and ...
1565
1077
ISOLATION, PURIFICATION AND CHARACTERIZATION OF BIOACTIVE COMPOUNDS FROM STACHYTARPHETA URTICIFOLIA (SALISB.) SIMS
Natural products from various medicinal plants, in the form of pure compounds or standardized extracts, which provide unlimited opportunities for discovery of new drug leads, is due to the unmatched availability of chemical diversity. There is an increasing demand for chemical diversity in screening programs, seeking therapeutic drugs from natural products, interest, particularly in edible plants,...
3588
1835
TO EVALUATE THE CHEMICAL CONSTITUENTS OF SHODITHA (PURIFIED) AND ASHODHITHA (RAW) DATURA METEL LINN ROOT – A ANALYTICAL STUDY
Datura (Datura metel Linn.) is a herbaceous leafy annual and short-lived plant of the Solanaceae family. It's commonly known as Angel's trumpet, Devils apple, Jimson weed, stinkweed, and Thorn apple. The traditional system of medicine enlightened the importance of Datura metel Linn. of its great medicinal value. The roots, leaves and flowering tops have been used in India for their narcotic and an...
2053
1083
ANTIOXIDANT, ANTI-ANGIOGENIC AND CYTOTOXIC EFFECT OF ALOE BARBADENSIS, A MEDICINAL PLANT FROM INDIA
Background: Aloe barbadensis (AB) is a member of the Liliaceae family, traditionally used for thousands of years in some parts of India and well known for its anti-inflammatory, antimicrobial, and wound healing properties. The purpose of the study is to evaluate the antioxidant, anti-angiogenic and antiproliferative effect of AB methanolic root extract on A549 lung cancer cell line. Methods: The A...
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