Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
LCMS/MS QUANTITATION OF CATECHOLAMINES AND THEIR PREDECESSORS FROM PORTULACA OLERACEA AND GOMPHRENA GLOBOSA
The plants Portulaca oleracea and Gomphrena globosa belong to the order Caryophyllales, and their flowers are known to produce betalains. The biosynthesis of betalains involves various intermediate molecules such as catecholamines or biogenic amines. Catecholamines include dopamine, adrena-line (epinephrine), and noradrenaline (norepinephrine) and are normally believed to be released in response t...
1694
960
EVALUATION OF DETRIMENTAL FACTORS OF DRINKING WATER AND THE EFFECT OF BLOOD GLUCOSE LEVELS AND ANXIETY STATUS: AN EXPERIMENTAL STUDY IN WISTAR ALBINO RATS USING ELEVATED PLUS MAZE
This study is focused on evaluating the detrimental factors of drinking water and its relation to blood glucose level and anxiety status of non-stressed experimental rats. The study was conducted on 30 adult Wistar albino rats. The control group was treated with filtered water by reverse osmosis unit, and test 1, test 2, test 3, and test 4 groups were treated with well water from rural area 1, r...
1713
937
ENHANCEMENT OF BIOACTIVE CRUDE COMPOUND PRODUCTION BY STATISTICAL OPTIMIZATION OF FERMENTATION PARAMETERS FROM STREPTOMYCES SP. NLKPB45 ISOLATED FROM MARINE SOIL SEDIMENT
Actino bacterium Streptomyces sp. NLKPB45, which was isolated from mangrove soil sediments of Nellore coastal regions of Andhra Pradesh, India, was used in shake-flask fermentation to explore the different carbon and nitrogen substrates for antimicrobial crude compound. Careful experimentation of ranging each variable in the fermentation medium found that glucose and peptone as preferred carbon an...
1549
915
PHARMACOPHORE BASED MODELLING OF PYRIDINE-PYRIMIDINE ANALOGS AS MER TYROSINE KINASES INHIBITORS IN ANTICANCER THERAPY
MER kinase is an important tyrosine-kinase receptor that is associated with a variety of cancers, including mantle cell lymphomas, pituitary adenomas and T-cell acute lymphoblastic leukemia. Identification of new MERTK inhibitors assumes crucial importance. Only one ligand-based pharmacophore model is reported to date for MERTK inhibitors. There are many more molecules with improved enzyme inhibit...
1869
1049
FORMULATION AND EVALUATION OF PROPRANOLOL HYDROCHLORIDE ORAL DISINTEGRATING TABLETS
Background and purpose of the study: Propranolol hydro-chloride beta-adrenergic receptor antagonist utilized in the treatment of high blood pressure, atrial fibrillation, myocardial infarction, angina and migraine headaches. The pharmacokinetic parameters make Propranolol hydrochloride an appropriate candidate for oral disintegrating tablets. This work aims to develop orally disintegrating tablets...
3329
1921
STUDIES ON ANTIMICROBIAL ACTIVITY OF HIBISCUS SPECIES OF KARNATAKA AGAINST CLINICAL ISOLATES
Antimicrobial activity of the various species of Hibiscus like Hibiscus sabdariff, Hibiscus rosa-sinensis, Hibiscus trionum, Hibiscus cannabinus, Hibiscus mutabilis against various pathogens like Staphylococcus aureus, E. coli, Bacillus subtilis, Streptococcus species, Salmonella typhimurium, Klebsiella pneumonia, Pseudomonas aeruginosa, Serratia marcescens, were studied with the help of agar well...
1935
1007
AN OPTIMIZED HERBAL FORMULA DIMINISHES CCL4-INDUCED HEPATOTOXICITY IN RATS BY INHIBITION OF LIPID PEROXIDATION AND P53-MEDIATED APOPTOSIS
Introduction: In this present study, the heaptoprotective effect of an optimized herbal formula (HF) was evaluated against carbon tetrachloride (CCl4)-induced liver injuries in rats. Methods: In-vitro antioxidant activity of the HF was evaluated by reducing power, lipid peroxidation, and DPPH scavenging assays. Hepatoprotective activity of HF (100, 200 and 400 mg/kg b.w) was evaluated against CCl4...
1685
808
A SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM FOR IMPROVEMENT IN ORAL BIOAVAILABILITY OF NIMODIPINE: IN-VIVO EVALUATION
The current research involves the study of a Nimodipine self-nanoemulsifying drug delivery system (SNEDDS) with improved bioavailability and solubility. Fifteen formulations of Nimodipine SNEDDS were prepared prior to evaluation of particle size, emulsification time, percentage drug release, percentage transmittance, thermodynamic stability and in-vitro drug release. The formulation F13 was chosen...
1693
987
QUANTITATIVE AND QUALITATIVE PHYTOCHEMICAL ANALYSIS IN BARK OF NOTHOPEGIA RACEMOSA (DALZ.) RAMAM. COLLECTED FROM GADIKALLU, SHIMOGGA, KARNATAKA
Plants are a source of bioactive compounds produced by different parts of the plant, maybe bark, leaves, flowers, roots, fruits, and seeds, during metabolic activities. These secondary metabolites may have protective and disease preventive properties, hence used by Traditional practioner to treat various ailments. Most plants of the Western Ghats of India remain unknown, poorly understood or unest...
1926
1284
EFFICACY OF DRUGS IN DRUG-RESISTANT TUBERCULOSIS: A RETROSPECTIVE OBSERVATIONAL STUDY
Introduction: Drug-resistant tuberculosis (DR-TB) emerged from the time anti-tuberculosis drugs were discovered and used. It has become a formidable obstacle in the eradication of tuberculosis. India is in second position after China with tuberculosis, where about 20% of patients with DR-TB were not treated due to inappropriate coordination and diagnostic facilities. Method and Materials: A retros...
1601
742