Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
SOLUBILITY ENHANCEMENT AND DEVELOPMENT OF DISPERSIBLE TABLET OF CANDESARTAN CILEXITIL
Candesartan Cilexitil is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Candesartan cilexitil is a BCS class II drug having low solubility and high permeability. Candesartan Cilexitil is a prodrug which is rapidly converted to the active drug, Candesartan, by ester hydrolysis during absorption from the gastrointestinal tract. The bioavailability of Candesartan...
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DESIGN AND CHARACTERIZATION OF SOLID DISPERSED FEXOFENADINE HYDROCHLORIDE BUCCAL FILM BY CENTRAL COMPOSITE DESIGN
Fexofenadine Hydrochloride (FHCl) is a second generation antihistaminic drug which is used in the treatment of allergic rhinitis and urticaria. It is a BCS class II drug and has high first pass metabolism leading to low oral bioavailability. Drug-inclusion complex with 2HPβCD was prepared by kneading method and characterized for solubility study, FTIR study and in vitro dissolution study. Nine di...
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FORMULATION OF NATURAL MOSQUITO PAPER COIL AND EVALUATION OF MOSQUITOCIDAL ACTIVITY
The main aim of the present study is to formulate low cost natural mosquito paper coil and to evaluate the mosquitocidal activity of Annona squamosa leaf extracts. Annona squamosa Linn. is the plant belonging to the family of Annonaceae commonly known as custard apple. Several bioactive compounds have been isolated from the Annona squamosa leaf extracts reported to possess anti-diabetic activity, ...
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SOLUBILITY ENHANCEMENT AND DEVELOPMENT OF DISPERSIBLE TABLET OF CANDESARTAN CILEXITIL
Candesartan Cilexitil is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. Candesartan cilexitil is a BCS class II drug having low solubility and high permeability. Candesartan Cilexitil is a prodrug which is rapidly converted to the active drug, Candesartan, by ester hydrolysis during absorption from the gastrointestinal tract. The bioavailability of Candesartan...
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1269
FORMULATION AND EVALUATION OF ENCAPSULATED FLOATING BEADS CONTAINING THE FAMOTIDINE AS A MODEL DRUG
The aim of this research work was to formulate and optimize a floating drug delivery system of famotidine. In the present study, preparation of famotidine floating beads, in-vitro evaluation of Floating Drug Delivery System (FDDS), prediction of the release, and optimization of polymers ratio to match target release profile was investigated. An attempt was made to prepare oil entrapped floating be...
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BELINOSTAT: A HISTONE DEACETYLASE INHIBITOR FOR THE TREATMENT OF PATIENTS WITH RELAPSED OR REFRACTORY PERIPHERAL T-CELL LYMPHOMA
Histone deacetylase inhibitors (HDACIs) are a group of agents that have exhibited antitumor activity in vivo and in vitro, directing to clinical trials estimating their efficacy in multiple cancer types. Belinostat is under global development with Spectrum Pharmaceuticals, currently approved by the U.S. Food and Drug Administration with indications for relapsed or refractory peripheral T-cell lymp...
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GENUS HUNTERIA- A ETHNOPHARMACOLOGICAL, CHEMICAL AND PHARMACOLOGICAL PERSPECTIVES
Hunteria is a genus of plant in family Apocynaceae. It comprises of 12 species but more prevalent are Hunteria umbellata and Hunteria zeylanica. Taditionally H. umbellata have been used in the treatment of yaws and sexually transmitted infections, stomach ache, ulcers, diabetes mellitus and dysmenorrhoea. H. zeylanica is used to cure profile but its prolonged use, particularly, at high doses shoul...
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ZIKA VIRUS – A REVIEW ON PAST, PRESENT AND FUTURE SCENARIO
Zika virus is transmitted to people through aedes mosquito bites. People with Zika virus disease usually have symptoms of mild fever, exanthema (skin rash), joint pain and conjunctivitis that normally last for 2-7 days. There is no specific treatment or vaccine currently available. The best form of prevention is protection against mosquito bites. The virus is known to circulate in Africa, the Amer...
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A CASE CONTROL STUDY OF OXIDATIVE STRESS IN TUNISIAN PATIENTS WITH ISCHEMIC HEART DISEASE
Ischemic heart disease (IHD) is the major cause of morbid-mortality in most countries. The involvement of oxidative stress (OS) in the development of atherosclerosis, ischemic cardiopathy triggering phenomen, has been investigated. Serum total homocysteine (Hcy) concentration was measured by fluorescence polarization immunoessay. Plasma levels of substances reacting with thiobarbituric acid (TBARS...
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PHARMACOKINETIC DERIVATION OF RATES AND ORDERS OF REACTIONS IN MULTI-COMPARTMENT MODEL USING MATLAB
Pharmacokinetic modeling is the representation of the logarithmic mathematical equations in order to measure the physiologic response of the body to the drug. Absorption, distribution, metabolism and excretion follow drug kinetic principles according to specific reaction mechanisms in which concentration of the drug may either be dependent or independent of drug-body interactions. Michaelis-Menten...
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