Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
INFLUENCE OF FLUCONAZOLE PRE-TREATMENT ON ANTIDIABETIC ACTIVITY OF THIAZOLIDINEDIONES IN DIABETIC RATS
The influence of fluconazole pre-treatment on the hypoglycaemic effect of pioglitazone (10 mg/kg, p.o) and rosiglitazone (720µg/kg, p.o) was studied. This study was conducted on diabetic rats of either sex, randomly distributed into two different groups. Diabetes was induced by administering 120mg/kg of alloxan intraperitonially. Then they were pretreated with fluconazole (36 mg/kg) in 2% w/v gum...
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DESIGN AND IN VITRO EVALUATION OF PROCHLORPERAZINE MALEATE BUCCOADHESIVE TABLETS AND COMPARISON OF MONOLAYER, BILAYER AND COMPRESSED COATED TABLETS
Buccoadhesive tablets have long been employed to improve the bioavailability of drugs undergoing significant first pass hepatic metabolism. Prochlorperazine maleate is an anti-emetic drug. It was under goes extensive first pass metabolism resulting in an oral bioavailability of 0 to 16 % and it shows variable absorption from GIT. Hence in the present work Buccoadhesive bilayered tablets of Prochlo...
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CURATIVE EFFECTS OF MALOTILATE ON ETHANOL – INDUCED HEPATIC DYSFUNCTION IN RATS
In chronic alcoholics, continuous heavy drinking leads to progression of alcoholic liver disease (ALD) from alcoholic fatty liver, hepatitis to cirrhosis. Strict abstinence from alcohol has its own limitations and there is paucity of promising drugs available to treat ALD. Malotilate showed promising hepatocyte regenerating capacity and ability to prevent such damage. Aims: The objective of this...
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EVALUATION OF ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF SOME NUTRITIONAL SUPPLEMENTS
The nutritional supplements are the natural food supplements, and other related products used to boost the nutritional content of the diet. These nutritional supplements have been of interest to research because of their antioxidant property by consumption of food and drinks. The present study deals with a comparative evaluation of antioxidant and anti-inflammatory effects of marketed nutritional ...
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STUDIES ON ABOVE GROUND BIOMASS (AGB) FOR ASSESSING VEGETATION CARBON POOL IN TROPICAL FOREST ECOSYTEM OF CENTRAL INDIA
For estimation of carbon stocks in tropical forest types belonging to southern part of Madhya Pradesh, 30 adopted representative sites comprising eight districts viz, Jabalpur, Seoni, Balaghat, Narsinghpur, Mandla, Dindori, Shahdol and Umaria were selected for study and studies were carried out during 2009 to 2011. The study covered three types of vegetation i.e. teak mixed forest, sal mixed fores...
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FORMULATION AND CHARACTERIZATION OF DILTIAZEM HCL MATRIX TABLETS BY EMPLOYING ELECTROLYTES WITH GUM KONDAGOGU
The objective of the present investigation is to prepare and evaluate the sustained release matrix tablets of Diltiazem HCl using a natural polymer Gum kondagogu. Diltiazem HCl was formulated as sustained release matrix tablet formulations with natural polymer by employing pharmaceutically acceptable electrolytes. Electrolytes such as Sodium carbonate, Magnesium carbonate and Calcium carbonate wer...
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IDENTIFICATION AND CHARACTERIZATION OF E, Z ISOMERS FOR ACID DEGRADENTS OF SECONDARY ALCOHOL IN API BY HS/GC/ EI-MS
2º alcohols under acidic conditions (such as sulphuric acid) undergo degradation into E & Z isomers. There are many drug substances with sulphate as salt, and sulphuric acid is used for the preparation of sulphate of drug substance. Also, sulphuric acid is widely used in synthetic process for many drug substances. 2º alcohols are widely used as process solvents and as crystallization solvent...
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EVALUATION OF ANTI-NOCICEPTIVE AND ANTI-PYRETIC ACTIVITY OF AERVA PSEUDOTOMENTOSA LEAVES AQUEOUS EXTRACT
Aerva pseudotomentosa Blatt. & Hallb. (Amaranthaceae) is arid region plant commonly known as Bui. It is used in ethno medicinal practices for the treatment of pain and inflammatory hyperalgesic disorders such as rheumatic pain, fever, inflammation, wounds and urinary disorders. This study was conducted to evaluate the anti-nociceptive, antipyretic effects of A. pseudotomentosa leaves aqueous e...
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ZIKA VIRUS: A CHALLENGE FOR HUMANS
Zika virus infection is caused by the bite of an infected Aedes mosquito, usually causing rash, mild fever, conjunctivitis, and muscle pain. First time the virus was isolated in 1947 in the Zika forest in Uganda. It is transmitted to people through the bite of an infected Aedes mosquito. Symptoms are similar to those of dengue and chikungunya, which are transmitted by the same type of mosquito. Au...
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KAWASAKI SYNDROME- A REVIEW
Aim: The aim of this review is to provide a detailed documentation and main features such as prevalance, manifestations and management regarding Kawasaki syndrome. Background: Kawasaki Syndrome was first described by Dr Tomisaku Kawasaki in Japan in 1967, since then prevalence of Kawasaki syndrome is increasing in all countries as per the reports in journals. This is more prevalent in Asian pacifi...
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