Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
LESS TOXIC NANOPARTICLES OF PLATINUM BASED ANTI-CANCER DRUG
Objectives: The objective of this research was dose reduction and toxicity reduction. Dose reduction: various anti-cancer drugs are very costly, and their high dose increases cost. If bioavailability is enhanced, the dose shall be reduced thereby; the cost will also decrease. Dose reduction will also reduce toxicity, and the preparation will become more tolerable. Method: In this study, the nanopa...
2477
1150
MICROSCOPIC CHARACTERISATION OF ROOT, STEM AND LEAVES OF AN UNRESOLVED SPECIES: RUBUS INDICUS (ROSACEAE)
The genus, Rubus is considered as highly potent plant crop and possesses economical, medicinal and ecological importance. Rubus plant species have been utilized inbreeding programme and has identified various pharmaceutical compounds. However, the taxonomy of the genus Rubus has been in a state of flux, because of the absence of comprehensive work and associated taxonomic disputes. Among the genus...
1945
789
DESIGN, SYNTHESIS AND COMPARATIVE PHARMACOLOGICAL ASSESSMENT OF NOVEL FLUOROQUINOLONE DERIVATIVES
One of the proposed groupings of the fluoroquinolones describes the excellent broad-spectrum activity forms an invaluable part of the present anti-infective armory of the clinicians. The fluoroquinolones are most significant weapons can be credited for saving more human lives than any other area of medicinal therapy. In this current research segment, the novel C-3 substituted fluoroquinolone scaff...
1470
809
FORMULATION AND IN-VITRO CHARACTERIZATION OF 5-FLUOROURACIL AND FLAVONOID DUAL LIPID DRUG CONJUGATES LOADED SELF NANOMULSIFYING DRUG DELIVERY SYSTEM FOR CANCER TARGETING
Objective: The Failure in chemotherapy is mainly because of the resistance of the chemotherapeutic drugs towards the neoplastic cells. The main reason behind this study was to develop a novel combination of 5-Fluorouracil (5-FU) lipid curcumin conjugates for the treatment of cancer. Methods: In this study, the lipid group stearic acid and oleic acid was conjugated with the parent drug moiety 5-Flu...
1810
728
EVALUATION OF EFFECT OF AYURVEDIC PREPARATIONS ON NEPHROPATHY IN DIABETIC WISTAR RATS
Introduction: Type 2 diabetes, which is the most common type, is often a result of excess body weight and physical inactivity in genetically predisposed individuals. Over due course of time diabetes can cause blindness, kidney damage, neurological problems, and coronary artery disease. Improvement in glycemic control is important factors in delaying the onset and progression of diabetes-related co...
1830
657
ISOLATION AND STRUCTURAL ELUCIDATION OF DEGRADATION PRODUCTS OF RANOLAZINE
Degradation studies are important to know the potentials degradation products and to develop a stability indicating method. Ranolazine active pharmaceutical ingredients subjected to in detailed forced degradation study using several stressing agents (HCl, NaOH, H2O2). Degradation products of Ranolazine under hydrolytic and oxidative stress conditions were identified, and their stabilities were ass...
2091
1212
PHYTOCHEMICAL SCREENING, POLYPHENOLS CONTENT AND A NOVEL SOURCE OF ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF ESSENTIAL OIL OF LAURUS NOBILIS FROM MOROCCO
Bacterial resistance and oxidative stress are an important etiology of chronic diseases. This is the reason why new alternatives were established to overcome the incidence of some pathologies. Thus, the present study was aimed to evaluate the antibacterial activity of the extracted oil against bacteria that causes nosocomial infections in neonatal intensive care by using disc diffusion method. The...
1947
803
THE POTENTIAL ROLE OF FLAVONOIDS IN THE CONTROL OF OXIDATIVE STRESS FOR TYPE II DIABETES
Introduction: Antioxidant properties of flavonoids may guard against oxidative damage to cells, DNA, or lipids. The ample literature about flavonoids can affirm the structural and pharmacological cherishing of this class of phytochemicals. The presence of aromatic rings in the flavonoid molecule consent the receiving and donation of electrons from free radical species, which abets to curb the free...
1683
656
SELECTIVE ISOLATION AND CHARACTERIZATION OF NOCARDIOPSIS FLAVESCENS VJMS-18 FROM COASTAL REGIONS OF ANDHRA PRADESH, INDIA
Objective: To evaluate the antimicrobial potential of Nocardiopsis flavescens isolated from the marine environment. Methods: Attempts were made to isolate actinomycete strains from marine coastal regions of Andhra Pradesh, India. The soil samples collected were pre-treated with calcium carbonate, diluted and plated on three different media to isolate actinomycetes. All the isolates were screened f...
1686
681
COMPATIBILITY STUDIES BETWEEN PACLITAXEL AND EXCIPIENTS IN THE PREFORMULATION PHASE OF NANOCRYSTAL FORMULATION
Paclitaxel is one of the best anti-cancer drugs and recently known as the best anti-cancer products of natural origin. The purpose of the present work was to study the physicochemical properties and compatibility of paclitaxel with the selected surfactants employed in nanocrystal formulations. The melting point and loss on drying of paclitaxel were found 216 °C and 0.11% respectively. A log P val...
2098
1137