Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
TOPICAL DRUG DELIVERY OF KETOCONAZOLE ENTRAPPED TRANSFEROSOMAL GEL WITH DESIGN AND ENACTMENT
In pharmaceutical research, the transdermal route of drug delivery has gained great interest, Trasferosomes is a novel vesicular drug carrier system that is composed of water, surfactant, and phospholipids; these were introduced in the early 1990s. The mechanism on which drugs absorb through skin is “osmotic gradient”. Transferosomes, when applied on the skin surface it diffuses into skin laye...
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VALIDATED UFLC-MS/MS METHOD FOR THE QUANTITATIVE ESTIMATION OF PALIPERIDONE IN RABBIT PLASMA; ADAPTABILITY TO IN-VIVO BIOAVAILABILITY STUDY
A simple gradient ultrafast liquid chromatography-tandem mass spectrometry method was developed and validated for the quantitative estimation of paliperidone in rabbit plasma matrix as per USFDA, and EMA guidelines using a stable isotope-labeled paliperidone-d4 was added as an internal standard. The separation was achieved on a Hypersil BDS C18 column (4.6 mm × 10 cm, 5 µm) with the mobile phase...
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ANTI-MICROBIAL ACTIVITY AND FTIR SPECTROSCOPIC ANALYSIS OF ARGEMONE MEXICANA L. LEAVES EXTRACTS
The Screening of medicinal plants for the new bioactive compounds leads to the development of new anti-microbial drugs that possess lesser cost and greater safety and efficacy. The increasing bacterial resistance exhibited by microorganisms causing skin infections has led to the research on medicinal plants. Argemone Mexicana Linn is a weed that shows multiple health benefits. All the parts of the...
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NEUROPROTECTIVE EFFECT OF MADHUCA LONGIFOLIA LEAF EXTRACT AGAINST COLCHICINE: AN EXPERIMENTAL STUDY ON COGNITIVE DYSFUNCTION AND BIOCHEMICAL ALTERATIONS IN MICE
The goal of the research was to explain as a cognition enhancer the traditional claim of Madhuca longifolia (Sapotaceae) leaves. Dementia was activated by intracerebrovascular colchicine administration for 28 days. Madhuca longifolia leaves ethanolic extract was evaluated in mice for cognition-enhancing activity in colchicine-induced dementia using elevated plus maze (EPM), actophotometer, and bio...
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IN-VITRO STUDIES OF EXTRACTS OF PLUMBAGO ZEYLANICA IN CERVIX CARCINOMA CELLS
The present study evaluated the antimicrobial and cytotoxic activities of chloroform, hexane methanol, and petroleum ether extracts of Plumbago zeylanica (PEC, PEH, PEM, and PEP). Antimicrobial activities of the extracts were evaluated against gram-positive bacteria (Staphylococcus aureus-ATCC 6538 and Bacillus cereus-NCIM 2155) and gram-negative bacteria (E. coli-ATCC 8739) along with cytotoxicit...
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METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF CILNIDIPINE AND OLMESARTAN MEDOXOMIL IN TABLET DOSAGE FORM BY UPLC USING DAD
Olmesartan Medoxomil and Cilnidipine combination lowers blood pressure effectively. Olmesartan Medoxomil is an angiotensin receptor blocker (ARB), and Cilnidipine is a calcium channel blocker (CCB). Cilnidipine and Olmesartan Medoxomil are widely used in hypertension. The scope of the study is to optimize the chromatographic conditions to develop a new RP-UPLC method for the simultaneous estimatio...
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MAPPING PROTEIN INTERACTIONS BETWEEN RABIES VIRUS AND ITS HUMAN HOST
Rabies is a fatal viral disease which is caused by negative sense, single-stranded RNA virus belonging to Rhabdoviridae family of genus Lyssavirus, Rabies Virus (RABV). It is transmitted by the bite of a rabid animal and directly affects the CNS of the host (neurotropic). Sources of human rabies deaths are dogs (99%), cats, bats, etc. Rabies holds the seventh position in the world for causing the ...
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OPTIMIZATION OF CULTURAL CONDITIONS TO ENHANCE BIOACTIVE METABOLITE PRODUCTION BY STREPTOMYCES OLIVOVERTICILLATUS VLK-15
The study was designed to optimize cultural conditions for enhanced production of bioactive compounds by Streptomyces olivo-verticillatus VLK-15 isolated from mangrove ecosystem of South Coast of Andhra Pradesh, India. The soil dilution plate technique was employed for the isolation of actinobacteria using starch-casein agar (ISP-6) medium. The potent strain was identified as Streptomyces olivov...
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DEVELOPMENT AND VALIDATION OF FIRST-ORDER DERIVATIVE UV-SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF FLUVASTATIN SODIUM IN FORMULATION
A simple, accurate, precise and sensitive first-order UV - Spectrophotometric assay method has been developed and validated for the quantitative estimation of fluvastatin sodium in pharmaceutical dosage forms. The solvent to dissolve the drug and for dilutions, methanol was used. The absorption maxima of fluvastatin sodium in methanol after derivatized into the first-order derivative was found to ...
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NEUROPHARMACOLOGICAL EVALUATION OF INTRANASAL GUAR GUM LOADED OLANZAPINE MICROSPHERES
Background: The present work aimed to evaluate the sustained release antipsychotic activity of formulated biodegradable mucoadhesive guar gum microspheres of atypical antipsychotic drug Olanzapine (OLZ) for intranasal delivery and to reduce the dose-related side effects of the drug olanzapine. Guar gum microspheres of Olanzapine were fabricated and designed by O/W emulsion solvent evaporation tech...
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