Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
EVALUATION OF PROTECTIVE EFFICACY OF PUNICA GRANATUM ON SHORT TERM Β-CYFLUTHRIN TOXICITY ON REPRODUCTIVE TISSUE OF MALE MICE
Pyrethroids are among the most extensively used insecticide. The widespread use of these synthetic pesticides has stimulated research into the possible existence of adverse effects related to reproductive activity. The present study was, therefore, undertaken to assess the effects of β- Cyfluthrin, a type II synthetic pyrethroid on testes, the main organ of male reproduction. Animals were divided...
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ISOLATION, IDENTIFICATION OF NON-POLAR TERPENES AND TOTAL ANTIOXIDANT ACTIVITY FROM CHLOROFORM EXTRACT OF BOUGAINVILLEA GLABRA LEAVES
This study reports the isolation and antioxidant activity of non-polar terpenes extracted from the leaves of Bougainvillea glabra choicy. To characterize the phytochemical constituents of Bougainvillea glabra leaves using the GC-MS method. The 95% ethanol extract was filtered, distilled, and concentrated to obtain the solid greenish residue. The residue was further fractioned by n-hexane, chlorofo...
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ANTIOXIDANT ACTIVITY OF CASSIA AURICULATA AND CASSIA FISTULA EXTRACT ALONG WITH WOUND HEALING ACTIVITY OF ITS POLYHERBAL FORMULATION
Due to emergent concerns about unhealthy consequences of chemicals in the health industry, the interest towards natural and herbal substances has been growing every day. In this study, the antioxidant effect of Cassia fistula [CFF] and Cassia auriculata [CAF] extract was evaluated. Also discover wound healing activity of polyherbal formulation (CFF and CAF). The antioxidant activity of the extract...
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IN-VITRO EVALUATION OF ANTIULCER ACTIVITY OF AQUEOUS EXTRACT OF MALVASTRUM TRICUSPIDATUM
There are several factors that may induce ulcers in human beings such as stress, chronic use of anti-inflammatory drugs, etc. Though in most cases, the etiology of ulcer is unknown, it has generally accepted that it is the result of an imbalance between aggressive factors and maintenance of the mucosal integrity through the endogenous defense mechanism. Thus, the search for a safe anti-ulcer drug ...
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FORMULATION, DEVELOPMENT AND IN-VITRO EVALUATION OF HYDROGEL BASED CONTROLLED RELEASE MATRIX TABLET OF PROPRANOLOL HYDROCHLORIDE
Hypertension is the most life-threatening disease amongst all lifestyle diseases. So, there is always a need for such a dosage that can release the drug for a long period from a single dose which will reduce the dose burden for the patient. The propranolol HCL is a non-selective beta-adrenergic blocking agent extensively used in various cardiovascular diseases. In the present study hydrogel matrix...
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MOLECULAR DOCKING STUDY ON SARS-COV-2 PROTEASE INHIBITION BY EXPLORING BIOACTIVE COMPOUNDS FROM DIFFERENT PLANTS
The novel human coronavirus which has been designated as SARS-CoV2 initially appeared in December 2019 in Wuhan, China causing a respiratory illness called COVID-19. The SARS-CoV2 is a β coronavirus belonging to the family Coronaviridae is a global public health emergency infecting many people all around the world, especially in India with more than 10.8 million cases. Henceforth there is an urge...
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DISSOLUTION METHOD DEVELOPMENT AND VALIDATION FOR DERACOXIB CHEWABLE TABLET USING UV SPECTROPHOTOMETRIC METHOD
Deracoxib is a coxib class of Non Steroidal Anti-Inflammatory Drug (NSAID). Like other NSAIDs, its effects are caused by inhibition of Cyclooxygenase (COX) enzymes. Deracoxib causes greater inhibition of COX-2 than of COX-1. The aim of this proposed method was to develop and validate the UV spectrophotometric method for the routine quality control check of API containing 25 mg Deracoxib intablet...
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SYNTHESIS, PHARMACOKINETIC AND PHARMACOLOGY OF MUTUAL PRODRUGS OF FENBUFEN AND PROPYPHENAZONE
Mutual prodrugs of fenbufen and propyphenazone were synthesized with the aim of getting better therapeutic index through avoidance of gastrointestinal problems and to check the efficiency of release of parent drug in the presence of spacer. These mutual pro-drugs were synthesized by direct esterification and by using glycine as a spacer. The title compounds (FP1 & FP2) were characterized by sp...
1421
822
FORMULATION DEVELOPMENT AND EVALUATION OF ATORVASTATIN CALCIUM LIQUISOLID TABLETS
The solubility and dissolution properties of any drug are vital determinants of its oral bioavailability. The aim of this study was to increase the dissolution rate of poorly soluble drug Atorvastatin calcium by delivering the drug as a liquisolid compact, prepared by using PEG as a solvent, Avicel PH 102 as carrier, silica, and lactose are used as coating materials. Sodium starch glycolate was us...
2031
1237
ISOLATION AND STRUCTURAL ELUCIDATION OF IMPURITY IN NEBIVOLOL
In the synthesis of Nebivolol [a mixture of (1RS, 1' RS)-1,1'-{(2RS, 2' SR)-bis(6-fluoro 3, 4-dihydro-2H-1-benzopyran-2-yl)} -2,2'-iminodiethanol] having four chiral centers, one crucial isomeric impurity at 0.88 RRT was observed in HPLC related substance analysis in gradient HPLC method. This impurity was isolated from synthesized crude impurity substance by preparative HPLC with chiral normal ph...
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