Posted by admin on Jun 30, 2025 in |
Background and Objectives: The aim of the study is to evaluate the comparison based on cost effectiveness of inhalers used for asthma managements. The study utilized prospective interventional sampling approach and included Patient above 18 years and below 60 years, outpatients and In-patients, Asthma patients with comorbid conditions and excluded Pregnant and lactating women, unwilling patients, Subjects with communication problem, terminally ill/ ICU patients, Patient having insurance. Results: The incidence of asthma was seen mostly in the patients of age category 48 years and older (30.6%). Most of the patients were from the upper middle category (59%). After giving proper counselling to the patients, it was clearly evident that there will be improvement in adherence (76.4%). The subjects (47.2%, n=68) were found to be highly satisfied with the treatment provided to them by the physician. The PFT values after adherence were found to be 84.118±12.647. The most common inhaler device was found to be (61.1%, n=88). The mean drug cost for Budesonide/Formoterol was found to be less compared to...
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Posted by admin on Jun 30, 2025 in |
Background: The study assesses pharmacological management of CAD in a tertiary care center, focusing on medication adherence and quality of life (QOL) among hypertensive female patients. Materials and Methods: A prospective observational study conducted at LPS Institute of Cardiology, GSVM Medical College, Kanpur, included 140 diagnosed CAD patients between September 2021 to November 2022. Results: Among 140 participants, 55 patients (39.3%) presented with Acute Coronary Syndrome (ACS): 35 with STEMI and 20 with NSTEMI/UA. The remaining 85 patients had stable angina, underwent diagnostic coronary angiography, or were admitted for post-intervention follow-up, indicating a broader representation of CAD spectrum in clinical settings. The age group 61–70 years was most affected (32.86%). Hypertension (64.3%), diabetes (48.6%), and smoking (29.3%) were the major risk factors. Statins (94.29%), clopidogrel (89.29%), aspirin (86.43%), beta-blockers (60%), and ACE inhibitors (53.57%) were the most prescribed medications. The analysis of QOL domains showed a positive association between medication adherence and physical, psychological, social, and environmental well-being. Conclusion: Adherence to evidence-based pharmacological therapy was high, but underutilization of...
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Posted by admin on Jun 30, 2025 in |
Background: The Gonadal Arteries most commonly arise from the abdominal aorta at the level of the second lumbar (L2) vertebra, supplying the testes and ovaries. The gonadal arteries variations are commonly seen in males on right side however there are few instances where there is variation in ovarian arteries seen in females which could be of importance. Aim of the Study: To re-evaluate the origin and courses of gonadal arteries in human cadavers and explain the developmental anatomy and its clinical significance. Materials and Methods: During routine educational dissection of 24 cadavers in the Department of Anatomy, K.A.P.V. Government Medical College, Trichy, the origin and course of gonadal arteries were observed. I found the variants in 2 female cadavers aged over 60 years. Results: The present study showed variation in the origin of ovarian arteries in 2 female cadavers (8.33%) out of 24 cadavers. I observed, a rare anatomical variant of left ovarian arteries were found, originating from the left accessory renal arteries, just below and behind the left...
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Posted by admin on Jun 30, 2025 in |
Dyslipidemia is a known risk factor for Atherosclerotic Cardiovascular Diseases (ASCVD). Statins are first choice drug for the treatment of dyslipidemia. The FDA advises a low starting dose of rosuvastatin at 5 mg/day in Asians. The present study is a randomized, open labelled study done at Victoria Hospital, Bangalore to compare the efficacy and safety of rosuvastatin 5mg versus atorvastatin 20mg in patients with dyslipidemia. A total of 60 treatment naïve adult patients with dyslipidemia were randomized into two arms of 30 each in 1:1 ratio to receive either rosuvastatin 5mg or atorvastatin 20mg. Lipid profiles at baseline and at 6th week follow-up visit was recorded. Efficacy was assessed by mean change in lipid parameters at the end of 6 weeks and safety by recording the number and severity of adverse events reported by the patient at any time during the study. Among the 60 patients the mean difference at 6th week from baseline for Total cholesterol, LDL, HDL and Triglyceride for the rosuvastatin and atorvastatin group were (mg/dl)...
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Posted by admin on Jun 30, 2025 in |
We present the case of a 25-year-old unmarried male driver diagnosed with recurrent genital herpes (RGH) and genital warts, associated with insulin-dependent diabetes mellitus (IDDM). The patient reported a history of unprotected sexual intercourse with a commercial sex worker (CSW) four months prior. He developed multiple painful genital erosions and verrucous growths on the penile shaft. Laboratory investigations confirmed HSV-2 and HPV infection. The patient was treated with oral acyclovir 800 mg four times daily for 7 days for RGH and topical imiquimod 5% cream thrice weekly for genital warts. The treatment resulted in complete resolution of symptoms without recurrence. This case highlights the importance of early diagnosis, targeted therapy, and preventive counseling in managing STIs, especially in immunocompromised individuals like diabetic patients. Additionally, it underscores the need for safe sexual practices, routine STI screening, and HPV vaccination to reduce disease burden and complications in high-risk...
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