Posted by admin on Aug 31, 2025 in |
Obesity has become a matter of quality to health care administrators. The busy lifestyle of people made them prefer fast food instead of taking healthy food. But the people are not aware that fast food habits convert to diseases like obesity, type 2 diabetes mellitus (T2DM), dyslipoproteinemia etc. This case-control study was carried out in the Department of Biochemistry in collaboration with the Department of General Medicine, Madhav Prasad Tripathi Medical College, Siddhartnagar to explore the status of blood sugar fasting (BSF), tumor necrosis factor-α (TNF- α), Insulin, Insulin resistance, antioxidant enzymes and lipoprotein profile by standard spectrophotometric kit methods, as well as anthropometric measurements, blood pressure (BP) with the help of suitable instruments and equipment’s in Control group and Obese with T2DM group. A marked impairment observed in levels of lipoprotein profile accompanied by an increase in the lipids and apo-protein levels of serum β lipoproteins, lipid peroxide, Insulin and Insulin resistance, blood pressure, anthropometric measurements following the decrease in lipid and apo-protein constituents of α lipoprotein. Also...
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Posted by admin on Aug 31, 2025 in |
Traditionally, alopecia, a major illness throughout the world, has been treated with medicinal plants and their oils. Hair treatments, including those that stimulate hair growth, cost about $10 billion a year. A big worry is hair loss, which is mostly brought on by junk food and erratic lifestyle choices. The function of the ethanolic extract of the entire A. indica plant is examined in this study. Polar components like alkaloids, flavanoids, glycosides, terpenoids, and salts were detected by qualitative screening after Soxhlet extraction. At the maximum dose of 2000 mg/kg, 14 rats in acute toxicity trials exhibited no behavioral abnormalities, a modest increase in weight, and no mortality. At 500 mg/kg and 1000 mg/kg doses, the in-vivo hair growth boosting activity on 24 rats demonstrated effectiveness in activating hair follicles, increasing the number of hair follicles, and promoting hair growth. The results of the study demonstrate the effectiveness of the entire A. indica plant and offer a formulation approach for creating hair...
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Posted by admin on Aug 31, 2025 in |
Background: The present investigation was aimed at developing, optimize and evaluate gastroretentive floating tablets containing Losartan potassium to retain in the stomach for prolong and predictable period of time for hypertensive patients. In the present study, the effect of HPMC K15M showed prolong release of drug in gastric pH environment. Results: These formulations were evaluated for the parameters like drug excipient compatibility study, thickness, hardness, tablet density, floating lag time, total floating time, weight variation test, % friability, drug content, % swelling index and accelerated stability studies. On the basis of preliminary results, the amount of HPMC K15M (X1) and the amount of MCC (X2) were chosen as independent variables in 32 full factorial design while % Friability (%F) and Cumulative % drug release at 12 hrs (Q12) were taken as dependent variables. Multiple linear regression analysis, ANOVA and graphical representation of the influence of factors by contour plots were performed using Design Expert. In-vitro release data were fitted to various models to ascertain kinetic of drug release. The...
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Posted by admin on Aug 31, 2025 in |
Breastfeeding mothers often experience milk leakage and discomfort, highlighting the need for innovative, sustainable and hygienic nursing pads. This study explores the potential of banana pseudostem fibre as a natural, eco-friendly material for nursing pads. The research involves the extraction, processing and characterization of banana pseudostem fibres, followed by the development of a novel nursing pad prototype. The water absorption and antibacterial properties of the banana pseudostem fibre were evaluated, showing a high-water absorption percentage (88.52%) and broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. The results demonstrate the suitability of banana pseudostem fibre as a sustainable and hygienic material for nursing pads. The developed prototype offers improved comfort, support, and absorbency, minimizing the risk of bacterial growth and infection. This research contributes to the development of eco-friendly, sustainable, and hygienic nursing pads, addressing the needs of breastfeeding mothers while promoting environmental...
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Posted by admin on Aug 31, 2025 in |
The prevalence of psychiatric disorders in AUD, the association between the severity of AUD and psychiatric disease, the influence of treatment of AUD on relief of psychiatric symptoms and vice-versa has been studied in various parts of the world. In India, the influence of various socio-economic factors and the lifestyle of the individuals is different to other parts of the world. There is paucity of the literature regarding the association of AUD with psychiatric disease, influence of AUD on pharmacotherapy of psychiatric disorders, the quality of life of patients with co-existing AUD and psychiatric disorders. This review aims to study the association and co-occurrence of AUD and psychiatric disorders and influence of combined disorders on the...
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