Posted by admin on Aug 31, 2020 in |
As humanity is progressing, many new borne infections are borne, and the stability and efficiency of the human body are being tested. Today the World is fighting with a deadly Novel infection named Corona Virus Disease. The aim of this systematic review is to find out the efficacy of Nutritional Interventions against the infections caused in the body due to pathogens. Further, the recommendations can be made for further researches based on the evidence collected. To collect the data, electronic databases such as Scopus, Pub Med, NCBI, and web of science have been used. The peer-reviewed journals and newspaper reports are being cited with the English language. The papers were published from 1989 to 2020. Finally, a total of twelve studies were identified, and the pathways of all nutrient metabolisms are included in the study. The studies were mostly carried out in Asian and European countries on human as well as animals. All the studies except one supported the role of Nutrients in preventing and curing the infection caused...
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Posted by admin on Aug 31, 2020 in |
Benzimidazole, a fused heterocyclic moiety containing benzene and imidazole, has gained considerable attention in the field of medicinal chemistry due to its wide array of pharmacological activities. Be it as a antifungal, anticancer agent, proton pump inhibitors, anthelmintic, anti-microbial, analgesic, it has become an intrinsic part of the pharmaceutical world. The presence of Nitrogen in its heterocyclic ring has made it a more biologically active pharmaceutical agent. The fact that benzimidazole residue is a constituent of vitamin B12 supports its potential use in therapeutics. Benzimidazole derivatives are the structural isosters of naturally occurring nucleotides such as purine, allow them to interact effectively with the biopolymers of the living system such as proteins, enzymes, and receptors. Benzimidazoles exhibit significant activity as a potential anti-tumour agent, smooth muscle cell proliferation inhibitors, a treatment for intestinal cystitis, and in a diverse area of medicinal chemistry. The synthesis of novel benzimidazole derivatives remains as the main focus of medicinal research. This current review covers the chemistry and significance of benzimidazole and its derivatives,...
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Posted by admin on Aug 31, 2020 in |
This case-control study had undertaken to evaluate effect of Allium sativum in normal rats. In this study ethanol extract of Allium sativum had macerated with aqueous gum acacia (2%, w/v) suspension and fed orally (500 mg/kg b w p. o.) to male adult normal rats of charles foster strain for 15 days. Results of this study showing that alcoholic extracts caused no any significant reduction in blood glucose, total cholesterol, triglyceride, phos-pholipids, free fatty acid, lipid peroxide and no significant increased in post heparin lipolytic activity, but on the other hand as per pre-existing data and my published studies in diabetic patients and diabetic experimental animals showed that extracts exert all above effects significantly. That’s why it is very clear here if a healthy person will take natural products, it never causes hypoglycemia, hypolipidemia, and under the weight. Natural products also not cause any significant change in hepatospecific parameters. Thus, from this study, we conclude that natural products are safe, non-toxic, and free from side effects, in comparison to...
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Posted by admin on Aug 31, 2020 in |
Plumeria alba Linn. belonging to the family Apocynaceae (Dogbane family) is the flowering plant. P. alba is used as a purgative, rubefacient in rheumatism, asthma, piles, gonorrhea, blood disorders and tumors, mentioned in the traditional system of medicine. The present study was carried out to establish the pharmacognostic studies, physicochemical parameters along with a preliminary phytochemical screening of various extracts of P. alba leaves. The methanolic extract of the leaves of the plant was screened for anti-diarrheal potentiality. The macroscopical and microscopical characteristics of powdered drug were studied. The transverse section of leaf indicated the arrangement of various cells in epidermal, lamina, and midrib regions. The preliminary phytochemical screening of various extracts revealed the presence of phytoconstituents, including alkaloid, glycosides, phenolic and tannins, flavonoids, and sterols. The physicochemical parameters such as total ash and acid insoluble ash (9.5 and 7.3% w/w respectively), loss on drying (0.5% w/w), and extractive values water-soluble and alcohol-soluble (10.0 and 4.2% respectively) of powder drug were studied. These studies will be helpful to establish...
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Posted by admin on Aug 31, 2020 in |
Bastar is endowed with a unique blend of traditional knowledge and rich floral diversity. The region is known as the island of Shorea robusta, which is a key source for white and black truffle called Boda. It is also known as the black gold of the sal forest. It sets underground with the onset of early monsoon and is an edible mushroom with high protein, vitamin, and fiber with the low calorific value used by the local inhabitants as delicious food and in the amelioration of heart disease, blood pressure, and stomach disorder. Owing to its tremendous health benefits, the present study deals with the assessment of the protein content, isolation, and identification of fungi associated with boda. The qualitative analysis revealed that black boda contains more protein content than white boda. The quantitative estimation revealed the presence of 0.97 mg/ml and 0.33 mg/ml of protein for 0.2 mg weight of black and white boda, respectively. Further, the boda sample were inoculated on potato dextrose agar and incubated at...
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