The present investigation carried out in six villages of Almora district of Kumaun Himalaya regarding mild and native ethno-medicinal plants which were used by locals in their own traditional health care system. This study reveals the status of ethno-medicinal plants and their importance preserved by locals of Kumaun region. During the study it was observed that 47 species of medicinal plants belo...
TOLERANCE STUDY OF “SPIRULINE PLUS” AND EVOLUTION OF BIOLOGICAL PARAMETERS IN PEOPLE LIVING WITH HIV-1 FOR TWELVE MONTHS
Spirulina is an algae used in our country for people living with HIV (PLHIV) and it is known especially for its therapeutic immunostimulatory effects. Spirulina capsules produced locally enriched in zinc and selenium called "spiruline plus" were formulated and given to PLHIV. The objectives of this randomized placebo controlled trial were to assess the tolerance by reporting side effects and t...
The quality of education offered by Pharmacy institutions in the country varies widely. There are only a few institutions which maintain internationally recognized standard. A survey was conducted on the one hundred and twenty four (124) undergraduate Pharmacy students to determine their awareness and inclination towards Pharmacy as a career choice. Students were evaluated for the perception on th...
The approval of first-in-class proteasome inhibitor bortezomib in 2003, made possible the therapeutic validation of proteasome as a target for use in discovery and development of new treatment options in cancer, particularly haematological conditions like Multiple Myeloma. However, this breakthrough drug discovery suffered from a few limitations. As a result, the discovery of bortezomib not only i...
Synthesis of heterocylic compound has always drawn the attention of chemist over the years mainly because of their important biological properties. Particularly, the role of β–lactam which are endowed with unique structure and potent biological activity. The β-lactam heterocycles are considered as an important contribution of science to humanity since they have been constituents of living orga...
DETECTION OF ACTIVE CONSTITUENTS FROM THE LEAF EXTRACT OF LANNEA COROMANDELICA BY GC-MS TESTING AND ASSESSMENT OF ITS PHARMACOLOGICAL ACTIVITY
Lannea coromandelica (Anacardiaceae) is a tropical tree commonly called as Indian ash tree. Its various parts is said to possess medicinal property and used in Ayurveda and other ancient system of medicine for the treatment of various ailments including treatment of inflammation, gout, cholera, leprosy, vaginal troubles etc. Its Pharmacological study revealed anti-inflammatory, antimicrobial, hy...
Natural products have great potential against microbes and can be used to overcome the problem of drug resistant pathogens. They are helpful in reducing the toxicity of existing antifungal compounds. This present in vitro study demonstrated the synergistic effectiveness of Cassia fistula (CF) leaves extracts and fluconazole (Flu) against isolated Flu resistant strains (FRSs) of Candida albicans (C...
Tuberculosis (TB) is a disease caused by a bacterium called Mycobacterium tuberculosis. The bacteria usually attack the lungs. Tuberculosis is a global health threat and infecting about one third of the human population. Despite having a variety of anti-tuberculous drugs and availability of effective chemotherapy and Bacille-Calmette –Guerin (BCG) vaccine, tuberculosis remains a leading infect...
Bacterial Food Poisoning' is a common name given to predominantly gastro-intestinal infections which arise after the consumption of food or drink that is contaminated with disease-causing bacteria. Over 250 organisms are known to cause food borne illnesses. Ayurveda is an ancient medical science & has described the food poisoning indirectly in the form of Anna Vishaktata. The aims of present s...
ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF ANOGEISSUS LATIFOLIA WALL IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS
Aim: To evaluate the antidiarrhoeal activity of methanolic leaf extract of Anogeissus latifolia. Material and Methods: The methanolic extract was evaluated using rodent animal models like castor-oil induced diarrhoea and castor-oil induced enteropooling. The phytochemical constituents were also planned to screen by using standardized methods. The plant is traditionally used for the treatment of...