Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
STANDARDIZATION OF DASHAMOOLA KWATHA CHOORNA: A HERBAL COMPOUND DRUG USED FOR PARISHEKA IN SPASTIC CEREBRAL PALSY
Background: Dashamoola is a group of ten drugs i.e. Bilva (Aegle marmelos (L.) Corrêa), Patala (Stereospermum suaveolens (Roxb.) DC.), Agnimantha (Clerodendrum phlomidis L.f.), Shyonaka (Oroxylum indicum (L.) Benth. ex Kurz), Gambhari (Gmelina arborea Roxb.), Bruhati (Solanum nigrum L.), Gokshura (Tribulus terrestris L.), Kantakari (Solanum xanthocarpum Schrad. & H. Wendl.), Prishniparni (Ura...
4651
1062
SYNTHESIS, CHARACTERIZATION, INDUSTRIAL APPLICATION AND ANTICANCER ACTIVITY OF NEW N-MUSTARD SUBSTITUTED COUMARIN DERIVATIVES
A series of N-mustard substituted coumarin have been synthesized characterized and evaluated for their in-vitro cytotoxicity and anticancer activity against PC-3 human cancer cell lines. The methodology involves nucleophilic substitution of readily accessible 3-cyano-4-chloro coumarin with ethanol amine further on chlorination gives substituted 4-(bis(2-chloroethyl)amino)-2-oxo-2H-chromene-3-carbo...
2505
928
EFFECT OF COMBINED EXPOSURE OF DICHLORVOS AND MONOCROTOPHOS ON NEUROTRANSMITTERS AND ACETYLCHOLINESTERASE IN RAT
Organophosphate pesticides are associated with neurotoxicity. Organophosphates are cholinesterase-inhibiting chemicals used predominately as pesticides. These have played a very important role in sustainable production of food, animal feed and as protection against disease vectors. They are also used as chemical warfare agents (nerve agents). The effects of dichlorvos and monocrotophos on brain ne...
2224
786
SCREENING OF SULPHUR OXIDIZING BACTERIA FROM SULPHUR SPRINGS OF SAHASTRADHARA REGION OF DEHRADUN, UTTARAKHAND, INDIA
Sulphur water is commonly used as the remedial source for treating skin infections and eradicating pathogenic microbes causing infection. The sulphur water is the source of sulphur oxidizing bacteria which is the source of different secondary metabolites which has potential killing activity against different skin borne infections. In the present investigation, the study was performed to isolate an...
2949
840
SYNTHESIS OF MANNICH BASES OF NORFLOXACIN: CONVENTIONAL AND MICROWAVE ASSISTED SYNTHESIS
Quinolones are the organic compounds that act against the DNA-gyrase enzyme, a type II topoisomerase. Norfloxacin is one such quinolone which is characterized by a piperazinemoiety at C-7 position. This moiety plays a significant role in determining the antibacterial spectrum and potency and serves as a site amenable to significant modification. N-Mannich bases have proved to be potential prodrug ...
2098
1026
EXPLOITATION OF SECOND GENERATION SUPERPOROUS HYDROGEL COMPOSITES AS MATRIX RETARDANTS, IN GEL COATING OF PREGABALIN FORMULATION AND IN-VIVO CHARACTERIZATION
The hydro dynamically balanced gastro retentive systems of Pregabalin has been formulated and evaluated which can retard the release of drug based on Super Porous Hydrogel Composites (SPHC) thereby prolong the release rate specifically in the upper part of the GIT. Fast swelling highly porous SPHCs are synthesized by gas blowing technique. The swelling property, mechanical strength and release pro...
2003
889
HEPATOPROTECTIVE EVALUATION OF BIXA ORELLANA L. SEED EXTRACT AGAINST ACUTE ETHANOL-INDUCED HEPATOTOXICITY IN RATS
Disorders caused by excessive use of alcohol known as alcohol use disorders (AUD) are the most common cause of liver diseases including cirrhosis. In adults, the most common cause of death is alcohol consumption which leads to an array of alcoholic liver diseases (ALD). Present study has been conducted to investigate the hepatoprotective activity of Bixa orellana L. (BO) seed extract against acute...
2454
920
QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP STUDIES OF SULFADIAZINE- SALICYLALDEHYDE SCHIFF BASE AS AN ANTI-MYCOBACTERIAL AGENTS
Quantitative structure activity relationship is among the most widely used computational technology for analogue-based drug design. A molecular modelling approach using sulfadiazine- salicylaldehyde Schiff base analogue as anti-mycobacterial activity from recently reported literature were taken and was designed using MOE 2009.10. Sulfanilamide sulfa drugs have been shown to inhibit dihydropteroate...
2043
898
DESIGN, DEVELOPMENT AND EVALUATION OF A NEW POLYHERBAL MOUTH WASH FOR ANTIBACTERIAL POTENCY AGAINST ORAL BACTERIA
A new Polyherbal Mouth Rinse was formulated comprising of polyherbal extracts of grapes peel, neem, clove, fennel and ginger based on their traditional applications. The extracts used in the formulation and polyherbal mouth rinse both were subjected for anti-bacterial activity separately. Phytochemical tests and spectral studies of the extracts have indicated the presence of polyphenolic compounds...
3960
1076
SYNTHESIS AND QSAR STUDY OF NOVEL THIAZOLE MOIETIES HAVING ANTIOXIDANT ACTIVITY
Thiazoles derivatives are an important class of heterocyclic compounds, reported to possess a wide spectrum of biological activities. Moreover, thiazole nucleus occupies a very important place in the field of antioxidant agents. The above observations prompted us to synthesize some novel thiazole derivatives with various substitutions at along with heterocyclic rings in the same framework for syne...
1941
808