Ganoderma is a miracle edible mushroom with unique composition and miraculous health benefits. The investigation aimed to elucidate interactions for the active compounds of Ganoderma lucidum namely Ganoderol A, Ganoderol B, Ganoderal A and Ganoderic Acid Y with Lanosterol 14 alpha demethylase enzyme using molecular docking software Arguslab. The effect of ganomycin1 and 2 as an inhibitor against H...
The main roles of bile acids as amphiphilic molecules are the micellar solubilization of the lipids, in the course of the welding process and the regulation of cholesterol homeostasis, which is essential as a precursor for the synthesis of bile acids. From the hydrophobic and hydrophilic surfaces of bile acids directly depends the level of their attachment to the receptors, ion channels and their ...
Ethanolic extract of the aerial parts of Thymus serpyllum was evaluated for antioxidant activity. As many diseases in today’s world are due to free radicals, finding antioxidants of herbal origin can lead to development of safe herbal medicines for these diseases. Hydroxyl radical scavenging method was used to evaluate the antioxidant activity of Thymus serpyllum in the present study. The result...
SCREENING OF BIOACTIVE COMPOUNDS FROM LEAF OF CENCHRUS CILIARIS L. FROM THAR REGION OF RAJASTHAN, INDIA
Cenchrus ciliaris L. (Poaceae) commonly known as “Dhaman grass”, is a common famine food used during drought and scarcity of food in Rajasthan. The present investigation was carried out to determine the phytochemical composition of leaf of C. ciliaris using gas chromatography - mass spectrometry technique. The mass spectrum of the compounds found in the extract was matched with the national in...
EFFECT OF HUMIC AND SALICYLIC ACIDS ON OIL YIELD AND FLAVONOID GLYCOSIDE OF SAFFLOWERS (CARTHAMUS TINCTORIUS L.) AS MEDICINAL PLANTS GROWN IN IRAQ
This study was conducted to investigation the effect of humic acid and salicylic on oil yield and flavonoids glycoside of safflower plant (Carthamus tinctorius L.) grown in Iraq. After soil preparation the plant seeds were cultivated during winter growing seeds at 2015-2017 at Karbala region, South Baghdad in Iraq. The humic acid was applied at 1000, 2000 and 4000 mg/lit conception as organic flow...
A STUDY TO EVALUATE THE TOTAL ORGANIC ACID CONTENT IN URINE OF CALCIUM OXALATE RENAL STONE FORMERS AND NON STONE FORMERS
Renal stones disease is the most common disease of the urinary tract affecting about 10% of the global population. Renal stone disease is a common disorder that develops when the urine becomes overly saturated with certain microscopic substances that bind into hardened mineral deposits known as renal stones. The objective of our current study is to evaluate the total organic acids of urine of calc...
EFFECT OF METHYL PARATHION (AN ORGANOPHOSPHATE) ON BIOCHEMICAL CONTENTS OF FRESH WATER CAT FISH HETEROPNEUSTES FOSSILIS (BLOCH)
The present work was planned to study the effect of methyl parathion an organophosphate compound (OP) on biochemical contents of fresh water cat fish Heteropneustis fossilis. The exposure of fish to the sub-lethal concentrations of the toxicant methyl parathion was investigated and the variations were observed in biochemical contents in different tissues of the fish i.e. gill, liver, intestine, mu...
Polyherbal preparations (PHP) are known to express high effectiveness in a vast number of diseases. In view of this, present investigation was carried out to identify phytochemical constituents of PHP, prepared from the aqueous extract of test plant powders of Mimusops elengi Linn., Strobilanthes barbatus Nees, Indigofera zollingeriana Miquel and Dillenia indica Linn. Phytochemical screening o...
ASSESSING THE GENOTOXIC AND CYTOTOXIC RESPONSES OF THE H-29 CANCER CELL LINES ON THE ETHANOLIC EXTRACTS OF THE OYSTER MUSHROOM, PLEUROTUS OSTREATUS VAR. FLORIDA
Globally, colorectal cancer is the third most common known today. Lack of cheap, rapid, safe and reliable cancer treatments resulted to the continued pursuit to find natural sources of bioactive compounds that can be cytotoxic or damaging to the DNA of cancer cells. One of the potential resource is the edible oyster mushroom (Pleurotus ostreatus var Florida) reported to have medicinal properties. ...
DESIGN OF CONTROLLED RELEASE NON-ERODIBLE POLYMERIC ATENOLOL MATRIX TABLET USING MICROWAVE OVEN-ASSISTED SINTERING TECHNIQUE
The objective of the present study was to evaluate the effect of microwave sintering condition on matrix formation and subsequent drug release from polymer matrix tablet for controlled release. The Atenolol floating SR matrix tablets were prepared by using tragacanth, sodium bicarbonate, Eudragit S-100 and citric acid was incorporated as a gas generating agents. Atenolol controlled release tablets...