The present work is aimed to formulate Itopride HCl sustained release pelletsusing ethyl cellulose N50 such ashydrophobic polymer by employing the solution/suspension layer technique. The drug excipients compatibility study was carried out by Furor Transform Infrared spectroscopy (FTIR) which reveals no interaction between drug and excipients. Total 12 batches were formulated. Six formulations wer...
Lycopersicon esculentum leaves had traditionally been used to stimulate hair growth in Lampung Pesisir tribes, Tanggamus Regency, Lampung, Indonesia. This study aimed to examine the active compounds from the n-hexane L. esculentum leaves. The study based on our previous research showing that the n-hexane had hair growth stimulating effects. The study started with sample collection, extracted by ma...
Adenocalymma alliaceum is an important medicinal plant belongs to the family Bignoniaceae. The antibacterial and phytochemical studies on the leaves of this plant were carried out by using the disc diffusion method and Thin Layer Chromatography. The methanolic leaf extract showed a brown colored band on TLC plate with an Rf value 0.25 represents the presence of sulfide compound. The extract was te...
THE UNDERSTANDING AND ADHERENCE OF HIV-INFECTED PREGNANT WOMEN TO THERAPY IN A SOUTH-EASTERN STATE OF NIGERIA: A CROSS-SECTIONAL ASSESSMENT
Introduction: Appropriate understanding and adherence to antiretroviral regimens are important requisites to the presentation of good outcomes in the Prevention of Mother-to-Child Transmission (PMTCT) of HIV/AIDS. Objectives: This study aimed to evaluate the understanding and level of adherence to antiretroviral regimens among HIV-infected pregnant women. The factors that affect the level were als...
EFFICIENCY OF DIFFERENT SOLVENTS ON PHYTOCHEMISTRY PROFILE OF WATER MELON (CITRULLUS VULGARIS SCHRAD.) SEED EXTRACTS
Citrullus vulgaris Schrad. has occupied a popular place in the indigenous system of folk medicine because of its high nutritional and antioxidant properties. The study aims to elucidate the extractive yield percentage and screen the seed extracts of watermelon using different solvents for its phytochemical profile. The solvents selected were Methanol, Ethanol, Chloroform, Petroleum ether, Ethyl ac...
EVALUATION OF IN-VITRO ANTIOXIDANT AND ANTICANCER ACTIVITY OF MONOCHORIA VAGINALIS LEAVES ON Hep2 AND HeLa CELL LINES
The entire plant (Monochoria vaginalis (Burm. f.) C. Presl.) except root is being used as a vegetable and has been used in traditional Indian system of medication for treating various diseases. But there are not many scientific data on the antioxidant and anticancer activity of M. vaginalis. Therefore, we aimed to determine the in-vitro antioxidant and anticancer activity of methanolic extract of ...
One of the major advances in vesicle research was the finding that some modified vesicles possessed properties that allowed them to successfully deliver drugs in deeper layers of skin. Transdermal delivery is important because it is a noninvasive procedure for drug delivery. Further, problem of drug degradation by digestive enzymes after oral administration and discomfort associated with parentera...
The scenario of pharmaceutical drug delivery are expeditiously challenging, but conventional pharmaceutical dosage forms are still dominating. Immediate release dosage forms are those wherein ≥85% of labeled amount dissolves within 30 min. Superdisintegrants are used to improve the efficacy of solid dosage forms. The basic approach used in the formulation of the tablet is the use of superdisinte...
The current study focuses on evaluating chemical composition and antimicrobial activity of seed oil of Broussonetia papyrifera; a widely used Chinese medicinal plant. The chemical constituents of the oil were evaluated by GC‑MS analysis. Antimicrobial activity and minimum inhibitory concentrations were determined by disk diffusion and agar dilution methods. The seed oil contains 46 different p...
QUALITY CONTROL, CHEMICAL COMPOSITION AND ANTIOXIDANT ACTIVITY OF SOME MARKETED PEPPERMINT OIL SAMPLES
This work aimed to evaluate the quality of some commercial peppermint oil products available in the Egyptian market. Also, analysis of peppermint oil extracted from Mentha piperita L. leaves marketed in Egypt. Thus, quality control of both herb extracted and purchased oil products. Essential oils were analyzed using GC/MS, and the main ingredients of each peppermint oil sample were quantified. The...