Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW BENZOTHIAZOLE DERIVATIVES
Some new hydrazino group substituted benzothiazole derivatives have been synthesized and their characterization was done by IR, NMR and MASS spectral data. The antimicrobial activities of these synthesized compounds was done by cup-plate diffusion method in DMSO against some Gram positive and Gram negative bacteria. Some of synthesized derivatives exhibited potent activity when compared with stand...
4989
1814
PHARMACOGNOSTICAL EVALUATION OF TRIBULUS TERRESTRIS L.
Objective: The present study was designed to evaluate the pharmacognostical and quality control parameters of Tribulus terrestris L. whole plant except fruits. Method: The plant was collected from the university campus and was got authenticated from NBPGR, Delhi. Various standardization parameters viz. loss on drying, ash values, extractives values, swelling index, foaming index etc. were determin...
7683
2315
FORMULATION AND EVALUATION OF PULSATILE DRUG DELIVERY SYSTEM CONTAINING DOMPERIDONE AND PARACETAMOL
The objective of the study to formulate and evaluate of pulsatile drug delivery containing combination of domperidone and paracetamol for the treatment of migraine which is used to deliver the drug at specific time as per pathophysiological need of the disease and improvement of therapeutic efficacy and patient compliance. Domperidone and paracetamol in the core tablet was formulated with differen...
5223
1817
PREPARATION AND CHARACTERIZATION OF pH/TEMPERATURE SENSITIVE MICROCAPSULES BY INVERSE EMULSION POLYMERIZATION
The pH/temperature sensitive microcapsules were prepared by inverse emulsion polymerization, in which sodium alginate (SA) and N-isopropyl acrylamide (NIPAm) were used as the wall material and pentoxifylline as a model drug. The effects of the emulsifier content on the particle size distribution and drug release property of microcapsules were discussed in detail. The structure, morphology, particl...
4541
1529
EVALUATION OF ANTIANAPHYLACTIC ACTIVITY OF VARIOUS EXTRACTS OF WITHANIA SOMNIFERA IN RATS
Antianaphylactic activity of Withania somnifera was investigated by using rat peritoneal mast cells. The investigation was carried out by presensitization of the rat by using sheep serum and tripple antigen. Sensitization induces mast cell degranulation. The rats which were pretreated with standard drug, prednisolone (10 mg) and different extracts (petroleum ether, methanol and aqueous extract) of...
4242
1617
MOLYBDENUM BLUE METHOD FOR THE SPECTROPHOTOMETRIC DETERMINATION OF LEVETIRACETAM- CALCIUM CHANNEL MODULATOR
A simple, accurate, precise and easy spectrophotometric method for the determination of levetiracetam in pharmaceutical formulations using molybdenum blue method was developed by the authors. Aqueous solution of the drug sample on reaction with ammonium molybdate solution and hydrazine sulphate solution on heating for 5 minutes at a temperature of 60 0 C gave a clear, stable and intense blue color...
6952
2221
FORMULATION AND IN VITRO EVALUATION OF GASTRORETENTIVE FLOATING DRUG DELIVERY OF VALSARTAN USING HOT MELT EXTRUSION TECHNIQUE
The aim of present study is to improve the aqueous solubility of valsartan by utilizing hot melt extrusion technique (HME). Hot melt extrudates were prepared by novel polymeric matrices such as HPMCAS and Plasdone S630 copovidone at different ratios. The solubility studies of extrudates, showed a significant improvement in aqueous solubility. Gastroretentive floating tablets of valsartan using its...
4403
1960
ALLOPURINOL INDUCED TOXIC EPIDERMAL NECROLYSIS
Adverse drug reactions in the form of toxic epidermal necrolysis is a rare but potentially fatal disorder. The pathophysiology of such reactions are not properly understood. There are many drugs which are very often implicated for causing such severe reactions. Allopurinol is a common drug used in chronic gout but also notorious for causing Steven - Johnson syndrome and rarely toxic epidermal necr...
5401
1700
ESSENTIAL OILS EFFECT IN COMBINATION WITH ANTIBIOTICS AGAINST STAPHYLOCOCCUS AUREUS ATCC 29213 BIOFILM SUSCEPTIBILITY
Staphylococcus aureus biofilm has been known as one inducing factor for the bacteria’s resistance to various antibiotics. One strategy which may increase the efficacy of the antibiotic is by combining the antibiotic therapy with antiinfective from natural resources. This research was evaluating the potency of three known antiinfective essential oil derived from leaves of Piper betle L., Ocimum b...
5081
1983
EXTRACTION, MOLECULAR DOCKING, HPTLC ESTIMATION AND IN VITRO EVALUATION OF UREASE INHIBITION POTENTIAL OF STEM BARK OF TERMINALIA ARJUNA
The extraction of stem bark of Terminalia arjuna using different extraction methods viz. room temperature extraction (RTE), soxhlet extraction (SE), Ultrasound assisted extraction (USAE) and microwave assisted extraction (MAE), estimation of the percentage yield of marker compounds arjunic acid and arjunolic acid present and in vitro evaluation of urease inhibitory activity of the extracts has bee...
4293
2685