Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
SOLUBILITY ENHANCEMENT TECHNIQUES: A REVIEW ON CONVENTIONAL AND NOVEL APPROACHES
Most of the drugs in the developmental pipeline are emerging from the High-Throughput Screening methodology resulting in increased molecular weights and thus consequential bioavailability problems. The bioavailability issue can be due to insufficient solubility of permeability. Most compounds face the solubility problems. Hence, with the advancement of chemical science, the need of development of ...
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A REVIEW ON HERBAL PLANTS AS IMMUNOMODULATORS
Herbal immunomodulator is substance which stimulates or suppresses the components of immune system including both innate and adaptive immune responses. The modulation of immune system by various medicinal plant products has become subject for scientific investigations currently worldwide. A number of Indian medicinal plants and various ‘Rasayana’ have been claimed to possess immunomodulatory a...
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CYCLODEXTRIN INCLUSION COMPLEX TO ENHANCE SOLUBILITY OF POORLY WATER SOLUBLE DRUGS: A REVIEW
Low solubility compounds show dissolution rate limited absorption and hence poor absorption, distribution and target organ delivery. Improvement of aqueous solubility in such a case is valuable goal to improve therapeutic efficacy. Complexation with CDs by different methods like physical mixing, melting, kneding, spray drying, freeze drying, co-evaporation has been reported to enhance the solubili...
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POMEGRANATE SEED OIL: A COMPREHENSIVE REVIEW ON ITS THERAPEUTIC EFFECTS
Pomegranate, Punica granatum L. (Punicaceae), as a medicinal and nutritional ancient fruit, has an outstanding medical history throughout the world. Each of compartments of pomegranate has interesting pharmacological activity. Juice, leaf, flower, and peels of pomegranate possess potent antioxidant properties, while juice, peel and oil are all weakly estrogenic activity. Pomegranate seeds have eth...
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FREEZE DRYING PROCESS: A REVIEW
Among the various methods of drying, this article has mentioned only one most important method, “Freeze drying”. This method is mainly used for the drying of thermo labile materials. This method works on the principle of sublimation. This method is divided into 3 steps for its better understanding; these are Freezing, Primary drying, and secondary drying. There are many advantages and disadv...
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THE INVASIVE WEED WITH HEALING PROPERTIES: A REVIEW ON CHROMOLAENA ODORATA
Chromolaena odorata or siam weed is regarded as one of the most harmful weeds present on earth. Many efforts are being made for the control of this weed. But, none of them have provided any significant success. It has been utilized in the traditional medicinal systems for its curative properties for centuries. Some of the current studies have revealed its medicinal properties which have lead to an...
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A DETAILED REVIEW ON ORAL MUCOSAL DRUG DELIVERY SYSTEM
Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora. Oral mucosal drug delivery system provides local and systemic action. In this review, attention is focused to give regarding physiology of oral mucosal including tissue pe...
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HYDROALCOHOLIC EXTRACTION OF MANGIFERA INDICA (LEAVES) BY SOXHLETION
The genus Mangifera indica belongs to the family Anacardiaceae and comprises of 40 species distributed in tropical and sub-tropical parts of South East Asia, Africa and Latin America The resin is useful in cutaneous disease .the juice of kernel is snuffed to stop nasal bleeding. A decoction of the leaves with a little honey added is given in aphonia, the loss of voice. Mid ribs of the leaves calci...
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PHYTOCHEMICAL SCREENING OF ACTIVE SECONDARY METABOLITES PRESENT IN WITHANIA SOMNIFERA ROOT: ROLE IN TRADITIONAL MEDICINE
Medicinal plants are a source of naturally active compounds used extensively by tribal people worldwide for many ailments. Withania somnifera (WS) is one such plant used to treat many ailments from the time of Ayurveda. Extraction of the bioactive plant constituents from the whole plant or from the different parts of the plant has always been a challenging task. As the dried roots of WSare w...
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A REVIEW ON PHARMACEUTICAL PREFORMULATION STUDIES IN FORMULATION AND DEVELOPMENT OF NEW DRUG MOLECULES
Preformulation is a group of studies that focus on the physicochemical properties of a new drug candidate that could affect the drug performance and the development of a dosage form. This could provide important information for formulation design or support the need for molecular modification. Every drug has intrinsic chemical and physical properties which has been consider before development of p...
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