Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
SCHIFF BASES DERIVED FROM 2-HYDROXY AND 2- METHOXY NAPHTHALDEHYDE: EXPLORATION OF IN SILICO DOCKING, DNA CLEAVAGE, ANTIBACTERIAL ACTIVITIES AND SAR
Antibacterial activities, molecular docking and DNA cleavage activities of five structurally related Schiff bases [L3 (a), L3 (b), L3 (c) L3 (d) and L3 (e)] were performed and their structure activity relationship was studied. Antibacterial activities of these compounds against gram-negative and gram-positive bacteria were evaluated by using well diffusion method and the compound L3 (c); 1-[(E)-(4...
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EFFECT OF CADMIUM EXPOSURE ON CHOLINERGIC SYSTEM AND ENERGY METABOLISM OF RAT BRAIN: REVERSAL EFFECT OF α-TOCOPHEROL
Cadmium (Cd) is a toxic heavy metal in the environment. The aim of this study was to investigate the potential effect of Cd on cholinergic and bioenergetic systems in three brain regions: cerebral cortex, cerebellum and hippocampus. The young albino rats (3 months) were exposed to low dose of Cd (1.5 mg/kg body weight) and high dose of Cd (3 mg/kg body weight) through intraperitoneal injection dai...
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COMPARATIVE STUDY OF HEPATOPROTECTIVE EFFECT PRODUCED BY CUMINUM CYMINUM AND NIGELLA SATIVA AGAINST CISPLATIN-INDUCED HEPATOTOXICITY; WITH HISTOPATHOLOGICAL STUDIES
Cisplatin is a cytotoxic drug which induced the hepatotoxicity in the albino mice when intra-peritoneally administered at the dose of 10 mg/kg. Administration of cisplatin raised the level of LFT’s enzymes and also reduced the level of antioxidant enzymes in the liver of the mice. Administration of Cuminum cyminum and Nigella sativa extract and silymarin remarkably showed the hepatoprotective ef...
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T-CELL ACTIVATION CONTROLLING EFFECTS OF ETHYL ACETATE FRACTION OF KALANCHOE PINNATA (LMK) PERS ON TMPD-TREATED LUPUS MICE
T-cell activation, with the low expression of CD62L (L-selectin) marker in the spleen, will increase B cell activity to produce lupus antibodies. Therefore, lupus patients need drugs which could increase the L- selectin expression in the spleen to reduce the auto-reactive T cell. The tested drug to increase the L-selectin in this research was the ethyl acetate fraction of Kalanchoe pinnata (Lmk) P...
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DNA- BINDING AND CLEAVAGE STUDIES OF Mn(II) AND Co(II) COMPLEXES OF 1-(2,5-DIOXOPYRROLIDIN-1-YL)(4-HYDROXY PHENYL)METHYL) THIOUREA)
A novel Mannich base ligand 1-(2,5-dioxopyrrolidin-1-yl) (4-hydroxy phenyl)methyl)thiourea (PSTU) and its Manganese (II) and Cobalt (II) complexes have been synthesized and characterized by elemental analysis, molar conductance measurements, magnetic susceptibility measurements, FT-IR, 1H NMR and 13C NMR spectroscopic studies. The antimicrobial activities and antioxidant activities of the free lig...
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STUDIES ON ANTI-INFLAMMATORY EFFECT OF MESUA FERREA LINN. IN ACUTE AND CHRONIC INFLAMMATION OF EXPERIMENTAL ANIMALS
Mesua ferrea Linn. (M. ferrea) is an endemic medicinal plant used for the treatment of inflammation, rheumatism, bronchitis, fever, headache, asthma and skin diseases. The aim of this study was to investigate the anti-inflammatory activities of 80% ethanol extract from stem bark of Mesua ferrea Linn. using animal models. Female Wistar albino rats weighing (150-200g) were used for the study. Anti-...
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1-[3/-(SUBSTITUTED PHENYL) -5/- (AMINO PYRIMIDINE)]- 3- (4/-NITRO PHENYL) 5-(SUBSTITUTED PHENYL)- 2-PYRAZOLINES: SYNTHESIS, CHRACTERISATION AND ANTIMICROBIAL SCREENING
In the present study eight novel 2-pyrazoline - amino pyrimidine hybrids have been synthesized in order to search new chemical entities with increased pharmacological properties. The targeted analogues were synthesized in four steps; Claisen-schmidt condensation of 4-nitro acetophenone with different benzaldehydes in basic medium to yield precursor chalcone which was cyclised using hydrazine hydra...
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PAEDIATRICIANS COGNIZANCE ABOUT THE DELETERIOUS EFFECT OF ANTIBIOTICS AND DENTAL CARIES – A PRELIMINARY STUDY
Aim: To evaluate pediatricians’ cognizance about the use of antibiotics and dental caries. Materials and Method: 200 Pediatricians’ who were willing to participate were selected randomly from public and private medical hospitals in South India. A pretested questionnaire was distributed to the Paediatricians’ and was personally contacted to receive the responses within a week’s time. Descri...
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ENHANCED ANTIMICROBIAL ACTIVITY OF PROBIOTICS THROUGH SELENIUM NANOPARTICLES ENRICHMENT AGAINST GASTROINTESTINAL PATHOGENS
The decrease in susceptibility towards commonly administered antibacterial agents is due to excessive use of antibiotics every now and then, due to which the resistance toward these antibiotics is developed in pathogens. To overcome the problem of resistance in pathogenic microbes, the study of incorporation of Selenium metal to probioticts supplement was carried out. Antimicrobial activity of ind...
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INVESTIGATING THE LINK BETWEEN TRANSFORMATIONAL LEADERSHIP, PSYCHOLOGICAL EMPOWERMENT, AFFECTIVE COMMITMENT AND ORGANIZATIONAL CITIZENSHIP BEHAVIOR IN THE PHARMACEUTICAL SECTOR OF INDONESIA
Modern organizations face increasing competition due to globalization, technological change, politics and economics. In order to cope with these, public organizations, including organizations at the central and local government levels, must improve their efficiency and performance to reflect the presence of organization in other countries. Leaders, therefore, must act more quickly in encouraging a...
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