Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
QUALITY CONTROL OF PYRAZINAMIDE IN FORMULATION USING MICELLAR LIQUID CHROMATOGRAPHY
Pyrazinamide is an important anti-tubercular drug which shortens the course of TB chemotherapy. A direct injection liquid chromatographic method is developed for the determination of pyrazinamide in pharmaceutical formulation. The method includes a micellar mobile phase containing 0.15M sodium dodecyl sulphate and 1% butanol (v/v) buffered at pH3, a Princeton SPHER-100 C18 column (250mm × 4.6mm, ...
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ANTI-BIOFILM ACTIVITY OF MIXED ‘TRANSITION METAL (Mn, Fe, Co, Ni, Cu AND Zn) – CALCIUM TARTARATE’ COMPLEXES
A series of six new, mixed transition metal and alkaline earth metal complexes of the general formulation [MM/(C4H4O6)2.xH2O] (where M= Mn, Fe, Co, Ni, Cu and Zn, M/ = Ca ) are synthesized by using bidentate tartarate ligand and are characterized by different analytical techniques such as elemental analysis, TGA, FTIR, XRD, SEM, magnetic susceptibility study, UV-visible spectroscopy etc. All synth...
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TARGETING INFLAMMATORY PROTEINS USING IMMUNOMODULATOR FOR REGULATION OF HEPATOCELLULAR CARCINOMA MICROENVIRONMENT
Inflammation plays fundamental role in hepatocellular carcinoma (HCC) initiation, progression and metastasis. The over expression of pro-inflammatory factors like Tumor necrosis factor-α (TNF-α), selectin, (IL)-6, nuclear factor-κB, TGF-β can alter the hepatic microvasculature. Natural products such as polyphenols, alkaloids, flavonoids, and flavonols have the ability to interface microenviron...
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FABRICATION, CHARACTERIZATION AND PHARMACOLOGICAL ACTIVITY OF USNIC ACID LOADED NANOPARTICLES
Usnic acid is lichen metabolite. Lichen species are the source of usnic acid. It has Antitumor and Anti-proliferation activity. Usnic acid is poorly water soluble drug. So its dissolution and bioavailability is poor. To enhance dissolution and bioavailability of usnic acid nanotechnology has been adopted. So in this study usnic acid powder was formulated as a nanoparticle with the help of PLGA pol...
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SOLID DISPERSION OF ORAL CANDESARTAN CILEXETIL TABLETS FOR HYPERTENSION: DEVELOPMENT AND CHARACTERISATION
The main aim of this study was to prepare solid dispersion of Candesartan cilexetil so as to improve its solubility and dissolution characteristics in order to enhance its oral bioavailability. Solid dispersion was formed by fusion method. 9 formulations (F1-F9) were prepared using different carriers i.e. Sorbitol, Polyethylene Glycol (PEG 6000) and Poloxamer 407 at different ratios of 1:1, 1:3, 1...
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ANTIMICROBIAL INVESTIGATION OF SOME ARID ZONE PLANTS OF RAJASTHAN
In the present study, the inhibitory effect of crude ethanolic extracts from four plants viz. Bauhinia racemosa Lamk (stem bark and roots), Holoptelea integrifolia (Roxb.) Planch. (roots), Kirganelia reticulata (Poir) Baill. (Stem bark) and Phyllanthus maderaspatensis Linn. (whole plant) were undertaken against some test bacteria and test fungi using Disc Diffusion Method. The screening data indic...
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ANTITUMOUR AND ANTIOXIDANT ACTIVITY OF WRIGHTIA TINCTORIA (ROXB.) R. BR. LEAF OIL
The present study is based on the evaluation of preliminary phytochemical screening, antitumor, cytotoxic and antioxidant activities of leaf oil of Wrightia tinctoria (Oil B). The oil B from Wrightia tinctoria leaves was subjected to phytochemical screening tests by using standard procedures. The free radical scavenging activity of both the extracts was measured by using the 1, 1- diphenyl-2-picry...
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EFFECT OF PARTIAL FISTULECTOMY WITH KSHARASOOTRA APPLICATION IN THE MANAGEMENT OF BHAGANDARA (FISTULA-IN-ANO) – A CASE REPORT
Management of fitula-in-ano by fistulectomy is a surgical challenge due to its high re-occurrence rate. Application of Ksharasootra has been indicated in ano-rectal disorders particularly in the management of Bhagandara (Fistula-in-ano) in Indian system of medicine. Ksharasootra, a medicated thread, was prepared with Apamarga Kshara (Ash of Achyranthus aspera Linn.), latex of Snuhi (Euphorbia neri...
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MANAGING ALLERGIC RHINITIS IN CHILDREN THROUGH AYURVEDIC HERBAL MEDICINES
Allergic Rhinitis (AR) represents a common and serious health problem in pediatric age group in term of outpatient visit. The chronic nature of disease and its association with other comorbid conditions like asthma, eczema etc. has shown significant negative impact on quality of life, school performance and cognitive functioning in children which has influenced many parents to seek alternative the...
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ANTIOXIDANT ACTIVITY OF ETHYL ACETATE EXTRACT OF GENUS AMARANTHUS LINN.
Plants possess good antioxidant capacity to get rid of free radicals that cause many lifestyle diseases especially cancer. Assessment of Antioxidant activity of Amaranthus Linn. leaves were evaluated by using in- vitro model. In the present study evaluation of ethyl acetate of extract of Amaranthus Linn. leaves with the help of two In-vitro antioxidant models were carried out for Nitric-oxide sc...
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