Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
POSSIBLE RETRIEVAL OF ORGANOCHLORINE INDUCED RENAL TOXICITY IN FISH BY AQUEOUS ROOT EXTRACT OF WITHANIA SOMNIFERA: IN VIVO STUDY
The present study was aimed to assess the reno-protective impact of aqueous extract of root of Withania somnifera (WSR) commonly known as Ashwagandha against organochlorine induced renal toxicity in fish Clarias batrachus (Linn.).Fishes were exposed to 4ppb concentration of commercial brand Endocel, an organochlorine pesticide for one week and two week to prepare the toxic model. These toxic group...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF COUMARIN DERIVATIVES AS ANTI-INFLAMMATORY AGENTS
All the newly synthesized Coumarin derivatives have shown considerable anti-inflammatory activity. In the present research work, we synthesized a series of novel Coumarin derivatives. The Coumarin derivatives such as substituted 7-hydroxy-4-methyl-2H-chromen-2-one and substituted 6-chloro-7-hydroxy-4-methyl-2H-chromen-2-one were synthesized from substituted benzoyl chloride. The chemical structure...
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3697
PICOGRAM LEVEL QUANTIFICATION OF VARENICLINE IN HUMAN PLASMA SAMPLES BY LC–ESI-MS/MS
The objective of this research was to develop and validate a simple, sensitive and specific Liquid Chromatography – Tandem Mass Spectrometry (LC–MS/MS) quantification of Varenicline in human plasma using Varenicline -D4 as Internal Standard (IS). The analyte was separated on a Zorbax SB-C18, 4.6 x 75 mm, 3.5 μm, 80 Å column with an isocratic mobile phase of 5mM ammonium formate: acetonitrile...
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2412
STUDY OF NEUTRALIZATION OF ENZYMATIC ACTIVITY OF DABOIA RUSSELII VENOM BY VARIOUS PLANT EXTRACTS AND THEIR COMBINATIONS USING IN VITRO METHODS
Snakebite is an important cause of morbidity and mortality and is one of the major health problems in India. Russell’s viper (Daboia russelli) appears to be the commonest cause of fatal snakebite in many Asian countries and especially in the Indian subcontinent. Intravenous administration of anti venom serum neutralizes the systemic actions, but it is of little effect on the reversal of local sy...
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A CASE CONTROL STUDY OF ANTIOXIDANT AND OXIDANT STATUS IN TUNISIAN RHEUMATOID ARTHRITIS PATIENTS
Rheumatoid arthritis is a chronic inflammatory disease with several triggers such as oxidative stress. The aim of this study was to assess the antioxidant enzyme activities (superoxide dismutase, glutathione peroxidase, glutathione reductase and catalase), the total antioxidant status, lipid peroxidation (malondialdehyde) and homocysteine levels in patients with rheumatoid arthritis. The study pop...
3872
1714
EVALUATION OF ANTI- HYPERGLYCAEMIC ACTIVITY OF MAYTENUS EMARGINATUS WILLD LEAVES EXTRACT ON STREPTOZOTOCIN-INDUCED DIABETES IN WISTAR RATS
Maytenus emarginatus Willd. Celeastraceae, popularly known as “Kankeri or kankero”, is a Thorny staff evergreen tree that is rich in various chemical constituents that determine the medicinal potential of this species. Diabetes mellitus is a disease that is affecting major population of the world. This study aimed to evaluate the antihyperglycaemic activity of the hydroalcoholic extract of the...
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1829
SANTALUM ALBUM: CLINICAL ASPECTS FOR TREATMENT OF CANDIDA INFECTIONS
Background: In present study, we aim to assess the anticandidal activity of crude extracts and screening of bioactive compounds and their identification by NMR, IR and GC-MS. Results: A total of 192 isolates were isolated from patients having oral and vaginal candidiasis and a total of 134 isolates showed positive results with Gram staining. The selected isolates APKU-2, APKU-3 and APKU-4 were ide...
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1894
COMPARATIVE PHARMACEUTICAL QUALITY CONTROL TESTING OF DIFFERENT BRANDS OF PARACETAMOL TABLETS AVAILABLE IN THE TRINIDAD & TOBAGO, WEST INDIES
Paracetamol tablets are popular over the counter (OTC) products among the patients as a good analgesics and antipyretics. The objective of this study was to compare the quality of the paracetamol tablet formulations those are locally available in Trinidad & Tobago pharmaceutical market manufactured by various pharmaceutical companies with pharmacopoeia standards. The four popular brands (A, B,...
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4294
EVALUATION OF CARDIO PROTECTIVE EFFECT OF AVERRHOA CARAMBOLA FRUIT IN ISOPROTERENOL INDUCED MYOCARDIAL INFARCTION IN RATS
Myocardial infarction develops due to ischemia induced oxidative stress. Averrhoa Carambola fruit (ACF) is reported to possess strong antioxidant activity which may protect the heart against isoproterenol (ISO) induced myocardial infarction (MI) in rats. To evaluate this activity Averrhoa carambolafruit extract (ACFE) (200mg/kg & 400mg/kg, p.o) was administered to male wistar rats (180-250g) f...
5016
1900
2D QSAR STUDY OF POTENT GSK 3β INHIBITOR FOR TREATMENT OF TYPE II DIABETES
The best QSAR model were generated with left of adept and significant descriptors like electronic, lipophilic and topological, using multiple linear regression (MLR) and partial least square (PLS), model further explained by using forward feed neural network analysis (FFNN). QSAR is a kind of technique that directly correlates in between chemical structure to their biological activity. The best ML...
9451
2035