Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
CYANOBACTERIA ASSISTED BIO-REDUCTION OF SILVER NANOPARTICLE CONJUGATES AND STUDY ON THEIR CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY AGAINST PATHOGENIC BACTERIA
Green nanotechnology has recently emerged as an area of research involving more eco-friendly and energy-efficient approaches for the synthesis of inorganic nanoparticles. The point of the present investigation is to evaluate the capacity of selected strains of freshwater Cyanobacteria (Microalgae) for their capability to biosynthesize silver nanoparticles by utilizing both live biomass of microalg...
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STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF ERTUGLIFLOZIN AND METFORMIN IN BULK AND PHARMACEUTICAL DOSAGE FORM BY ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY
A simple, accurate, precise method was developed for the simultaneous estimation of the Ertugliflozin and Metformin in Tablet dosage form. For the method development, Chromatogram was run through HSS C18 (100 × 2.1 mm, 1.7µ) column at a flow rate of 0.3 ml/min. and buffer used in this method was Ortho Phosphoric Acid buffer. The temperature was maintained at 30 °C. The optimized wavelength sele...
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STANDARDIZATION, FORMULATION DEVELOPMENT AND CHARACTERIZATION OF ANTIULCER DRUG: MUKTA BHASMA
Ayurveda is the holistic approach towards life, health, disease management through medicinal herbs minerals, diet and lifestyle leads to the great need for standardization of herbal medicine to maintain its safety and efficacy. Mukta bhasma is used in the treatment of bone metabolic disorders associated with calcium deficiency. It was prepared by Shodhana, Marana and Sharava samputa and the Standa...
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DRUG DEVELOPMENT AND OPTIMIZATION FORMULA OF RANITDIN HCl GASTRORETENTIVE MUCCOADHESIVE FLOATING SYSTEM TABLET
Ranitidine hydrochloride (RHCl) is a histamine H2 receptor antagonist, it’s widely in active duodenum ulcers, gastric ulcers, Zollinger-Ellison syndrome, gastroesophageal reflux disease, and erosive esophagitis. Ranitidine HCl has a short biological half-life of drug 2 - 3 h, has 50% absolute bioavailability, colonic metabolism of ranitidine HCl was partly responsible for the poor bioavailabilit...
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ANTIOXIDANT ACTIVITY OF A NEW FLAVONE GLYCOSIDE FROM THE STEMS OF GMELINA ARBOREA ROXB.
Gmelina arborea Roxb. belongs to the Verbenaceae family, commonly known as Gambhar. It is distributed throughout India, Ceylon, Malayan and Philippine Islands. Its roots have anthelmintic properties. Its flowers are useful in the treatment of leprosy and blood diseases. Its fruit has diuretic properties and aphrodisiac. It is also used in anemia leprosy and vaginal discharges. Leaves have shown an...
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ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ERTUGLIFLOZIN AND METFORMIN HCl IN BULK AND PHARMACEUTICAL DOSAGE FORM BY HPLC
Analytical method for simultaneous estimation of Ertugliflozin (ERT) and Metformin hydrochloride (MET) was developed and validated by high-performance liquid chromatography (HPLC) as per ICH guidelines. The drugs were injected into the inertsil C18 (250 × 4.6 mm) maintained at room temp and wavelength 220 nm. The mobile phase consists of buffer (potassium dihydrogen pH 4.0) and methanol (65:35 v/...
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PHYTOCHEMICAL STUDIES, FTIR AND GC-MS ANALYSIS OF HARDWICKIA BINATA ROXB. (FABACEAE / CAESALPINIACEAE)
Hardwickia binata belongs to family Fabaceae / Caesalpiniaceae and commonly known as ‘Anjan’. The present study includes phytochemical screening, FTIR and GC-MS analysis. Shade dried powdered leaves, seed and husk of H. binata extracted in petroleum ether, chloroform, ethyl acetate, acetone, methanol, ethanol, distilled water using Soxhlet apparatus and used for phytochemical analysis. Crude p...
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ANTIPLASMODIAL ACTIVITY OF AGANOSMA CYMOSA
Ethylacetate leaf extract of Aganosma cymosa was screened for antimalarial activities in-vivo in rats inoculated with red blood cells parasitized with Plasmodium falcipuram using 4-day Suppressive test and Rane’s test. The result of mean parasitemia by 4-day Suppressive test for the Group AC600, AC400 & AC200 was 4.62 ± 3.63, 13.34 ± 2.42, 19.29 ± 3.23 and percentage suppression were 80.1...
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CHEMOMETRIC APPROACH FOR RP-HPLC DETERMINATION OF DRONEDARONE USING RESPONSE SURFACE METHODOLOGY
The present study depicts the assessment of class III antiarrhythmic drug dronedarone in its drug substance and drug product. Response surface randomized central composite quadratic design has been employed for the optimization of method parameters using reverse-phase high-performance liquid chromatography (RP-HPLC) on Kromasil C18 250 × 4.6 mm, 5 µ with UV detection at 289 nm. The ranges of the...
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HIGH-THROUGHPUT STRUCTURE BASED VIRTUAL SCREENING TARGETING CNS FOR INHIBITED ACETYLCHOLINESTERASE REACTIVATION
Organophosphorus (OP) nerve agents blocks acetylcholinesterase and do not allow the degradation of acetylcholine. Post-treatment of organophosphate poisoning involves the treatment with oxime reactivators as an antidote, which will dephosphorylate the phosphate bond between enzyme and nerve agent. Due to CNS permeability failure of these oximes, the introduction of low molecular non-oximes has bec...
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