Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
HEPATITIS C VIRUS: AN OUTLINED REVIEW
Chronic hepatitis C (CHC) is a big cause of liver-related fibrosis and cirrhosis. The level of fibrosis is usually in the past (established by histology). The prognosis is estimated using fibrosis progression rates (FPRs; the annual probability of progressing across histological stages). However, new non-invasive options are quickly replacing biopsy. As the rates of HCV cirrhosis go on increasing ...
4943
1413
VIRUSES AS HIJACKERS
Viruses are like hijackers. They invade living, normal cells, and replicate and create other viruses like themselves using those cells. This can destroy, harm, or change the cells and cause sickness. Various viruses in the human body invade other cells, such as the liver, respiratory system, or blood. Viruses are too small germs. Inside a protein matrix, they are made of genetic material inside of...
3535
1326
MECHANISM OF DRUG INDUCED RENAL FAILURE: A REVIEW
Acute renal failure (ARF) is characterized by a rapid, potentially reversible decline in renal function, including a rapid fall in glomerular filtration rate (GFR) and retention of nitrogenous waste products over a period of hours or days. The mortality rate of patients with ARF has remained 25–70% despite the use of various pharmacologic agents. Due to the multiple causes of renal failure, many...
3631
1277
IMPROVEMENT IN BIOAVAILABILITY OF POORLY SOLUBLE DRUG BY SELF MICRO EMULSIFYING DRUG DELIVERY
Solubility is the rate-limiting step for bioavailability of poorly water-soluble drugs. The solubility of poorly water-soluble drugs can be enhanced by incorporating active pharmaceutical ingredients into oral lipid-based drug delivery systems. Self micro emulsifying drug delivery system (SMEDDS) is a researcher’s choice amongst other oral lipid drug delivery systems because it offers advantages...
2695
1686
TARGET TREATMENT IN DIABETIC AND MICROVASCULAR COMPLICATIONS: AN UPDATED REVIEW
Diabetes Mellitus is the most common endocrine disorder, affecting a larger population of the world, which arises due to defective insulin secretion by beta cells in the pancreas or insulin resistance by peripheral tissues. As the disease progress, microvascular complications like nephropathy, neuropathy, retinopathy, and cardiovascular complications are observed, which the leading causes of death...
2279
1195
SELF-EMULSIFYING SYSTEMS: A REVIEW
Effective delivery of drugs can be made through various routes of administration, and the oral route is considered to be the most convenient for the administration of drugs to patients. Poor aqueous solubility was acknowledged as the main reason for the poor oral absorption of chemical entities. Apart from the conventional solubilization approaches like co-solvency, salt formation, solid dispersio...
3380
2121
MOLECULAR VERSUS CONVENTIONAL TECHNIQUES FOR THE DETECTION OF STAPHYLOCOCCUS AUREUS, PSEUDOMONAS AERUGINOSA AND CANDIDA ALBICANS IN NON-STERILE PHARMACEUTICAL PREPARATIONS
Notable progress has been made in methods that encourage the use of PCR as a rapid and accurate tool in quality evaluation of pharmaceuticals. In this study, monoplex and multiplex PCR based assays were developed and compared with standard conventional methods for rapid detection of three specified topical indicator pathogens, Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans, in ...
2911
1441
NEUROPROTECTIVE EFFECT OF LEUCAS ASPERA IN STREPTOZOTOCIN INDUCED ALZHEIMER RAT MODEL
The present investigation deals with the assessment of neuroprotective effect Leucas aspera in streptozotocin (STZ) induced Alzheimer’s disease (AD) in rats. AD was induced by administering STZ (3 mg/kg, ICV) on day one and 3rd day after surgery. Surgery was performed on anesthetized rats with the help of the stereotaxic apparatus. STZ induced AD rats were treated with ethanolic extract of Leuca...
2662
1280
FORMULATION DEVELOPMENT AND CHARACTERIZATION OF MICROEMULSION OF EXTRACT OF E. NUDA
The compounds that are derived from the natural sources have been used for the treatment of cancer since ancient times. The tubers of Eulophia nuda, belonging to family Orchidaceae, have been reported for its anti-cancer use in the literature. There are many disadvantages to the conventional herbal drug delivery system. These disadvantages could be overcome by formulating these herbs using novel d...
3312
1763
MOLECULAR DOCKING STUDIES ON PHYTOCHEMICALS OF SOLANUM NIGRUM FRUITS FOR ITS HEPATOPROTECTIVE ACTIVITY
Liver fibrosis is a wound healing process that is initiated in response to chronic liver injury caused by viruses, toxins, and hepatotoxic drugs. This disease is characterized by inflammation, followed by the deposition of extracellular matrix proteins to form scar tissue. Ephrin receptor A2 (EphA2) is identified as a host cofactor for Hepatitis C Virus (HCV) entry. The fruits of Solanum nigrum po...
3271
1380